UA79921C2 - Composition of naltrexone microspheres for injections and use thereof for decreasing of heroin and alcohol consumption - Google Patents

Composition of naltrexone microspheres for injections and use thereof for decreasing of heroin and alcohol consumption Download PDF

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Publication number
UA79921C2
UA79921C2 UA2001117615A UA2001117615A UA79921C2 UA 79921 C2 UA79921 C2 UA 79921C2 UA 2001117615 A UA2001117615 A UA 2001117615A UA 2001117615 A UA2001117615 A UA 2001117615A UA 79921 C2 UA79921 C2 UA 79921C2
Authority
UA
Ukraine
Prior art keywords
microspheres
naltrexone
composition
poly
lactide
Prior art date
Application number
UA2001117615A
Other languages
English (en)
Ukrainian (uk)
Inventor
Thomas P Tays
Jay K Staas
Thereza M Ferell
Original Assignee
Brookwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brookwood Pharmaceuticals Inc filed Critical Brookwood Pharmaceuticals Inc
Publication of UA79921C2 publication Critical patent/UA79921C2/uk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
UA2001117615A 1999-04-09 2000-08-04 Composition of naltrexone microspheres for injections and use thereof for decreasing of heroin and alcohol consumption UA79921C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12847799P 1999-04-09 1999-04-09
PCT/US2000/009438 WO2000061147A1 (en) 1999-04-09 2000-04-08 Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol

Publications (1)

Publication Number Publication Date
UA79921C2 true UA79921C2 (en) 2007-08-10

Family

ID=22435553

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2001117615A UA79921C2 (en) 1999-04-09 2000-08-04 Composition of naltrexone microspheres for injections and use thereof for decreasing of heroin and alcohol consumption

Country Status (25)

Country Link
US (1) US6306425B1 (enExample)
EP (1) EP1171132B1 (enExample)
JP (2) JP4995371B2 (enExample)
KR (1) KR100621261B1 (enExample)
CN (1) CN1210031C (enExample)
AT (1) ATE262906T1 (enExample)
AU (1) AU780852B2 (enExample)
BR (1) BR0009639A (enExample)
CA (1) CA2369302C (enExample)
CZ (1) CZ20013636A3 (enExample)
DE (1) DE60009477T2 (enExample)
DK (1) DK1171132T3 (enExample)
EA (1) EA004734B1 (enExample)
ES (1) ES2218147T3 (enExample)
HK (1) HK1047245B (enExample)
HU (1) HUP0200838A3 (enExample)
IL (2) IL145802A0 (enExample)
MX (1) MXPA01010185A (enExample)
NO (1) NO328647B1 (enExample)
NZ (1) NZ515359A (enExample)
PL (1) PL196930B1 (enExample)
PT (1) PT1171132E (enExample)
TR (1) TR200102880T2 (enExample)
UA (1) UA79921C2 (enExample)
WO (1) WO2000061147A1 (enExample)

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Also Published As

Publication number Publication date
EP1171132B1 (en) 2004-03-31
JP2002541202A (ja) 2002-12-03
NO20014896D0 (no) 2001-10-08
EA200101062A1 (ru) 2002-04-25
BR0009639A (pt) 2002-02-05
KR100621261B1 (ko) 2006-09-13
PL350548A1 (en) 2002-12-16
CA2369302A1 (en) 2000-10-19
DE60009477T2 (de) 2005-02-24
WO2000061147A1 (en) 2000-10-19
NO20014896L (no) 2001-12-07
CN1354664A (zh) 2002-06-19
KR20020011975A (ko) 2002-02-09
EA004734B1 (ru) 2004-08-26
TR200102880T2 (tr) 2002-03-21
PT1171132E (pt) 2004-07-30
IL145802A (en) 2009-02-11
JP2010031036A (ja) 2010-02-12
ES2218147T3 (es) 2004-11-16
HK1047245B (zh) 2006-03-03
JP4995371B2 (ja) 2012-08-08
HUP0200838A2 (hu) 2002-07-29
MXPA01010185A (es) 2003-07-21
DE60009477D1 (de) 2004-05-06
DK1171132T3 (da) 2004-07-12
NZ515359A (en) 2002-10-25
CZ20013636A3 (cs) 2002-03-13
HK1047245A1 (en) 2003-02-14
HUP0200838A3 (en) 2005-07-28
EP1171132A1 (en) 2002-01-16
IL145802A0 (en) 2002-07-25
US6306425B1 (en) 2001-10-23
CA2369302C (en) 2007-09-25
CN1210031C (zh) 2005-07-13
AU4220300A (en) 2000-11-14
AU780852B2 (en) 2005-04-21
ATE262906T1 (de) 2004-04-15
PL196930B1 (pl) 2008-02-29
NO328647B1 (no) 2010-04-19

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