IL145802A0 - Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol - Google Patents

Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol

Info

Publication number
IL145802A0
IL145802A0 IL14580200A IL14580200A IL145802A0 IL 145802 A0 IL145802 A0 IL 145802A0 IL 14580200 A IL14580200 A IL 14580200A IL 14580200 A IL14580200 A IL 14580200A IL 145802 A0 IL145802 A0 IL 145802A0
Authority
IL
Israel
Prior art keywords
heroin
alcohol
naltrexone
reducing consumption
microsphere compositions
Prior art date
Application number
IL14580200A
Other languages
English (en)
Original Assignee
Southern Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Res Inst filed Critical Southern Res Inst
Publication of IL145802A0 publication Critical patent/IL145802A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14580200A 1999-04-09 2000-04-08 Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol IL145802A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12847799P 1999-04-09 1999-04-09
PCT/US2000/009438 WO2000061147A1 (en) 1999-04-09 2000-04-08 Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol

Publications (1)

Publication Number Publication Date
IL145802A0 true IL145802A0 (en) 2002-07-25

Family

ID=22435553

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14580200A IL145802A0 (en) 1999-04-09 2000-04-08 Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol
IL145802A IL145802A (en) 1999-04-09 2001-10-05 Injectable compounds of naltrexone microspheres and their uses in lowering heroin and alcohol consumption

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL145802A IL145802A (en) 1999-04-09 2001-10-05 Injectable compounds of naltrexone microspheres and their uses in lowering heroin and alcohol consumption

Country Status (25)

Country Link
US (1) US6306425B1 (enExample)
EP (1) EP1171132B1 (enExample)
JP (2) JP4995371B2 (enExample)
KR (1) KR100621261B1 (enExample)
CN (1) CN1210031C (enExample)
AT (1) ATE262906T1 (enExample)
AU (1) AU780852B2 (enExample)
BR (1) BR0009639A (enExample)
CA (1) CA2369302C (enExample)
CZ (1) CZ20013636A3 (enExample)
DE (1) DE60009477T2 (enExample)
DK (1) DK1171132T3 (enExample)
EA (1) EA004734B1 (enExample)
ES (1) ES2218147T3 (enExample)
HK (1) HK1047245B (enExample)
HU (1) HUP0200838A3 (enExample)
IL (2) IL145802A0 (enExample)
MX (1) MXPA01010185A (enExample)
NO (1) NO328647B1 (enExample)
NZ (1) NZ515359A (enExample)
PL (1) PL196930B1 (enExample)
PT (1) PT1171132E (enExample)
TR (1) TR200102880T2 (enExample)
UA (1) UA79921C2 (enExample)
WO (1) WO2000061147A1 (enExample)

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US6610317B2 (en) 1999-05-27 2003-08-26 Acusphere, Inc. Porous paclitaxel matrices and methods of manufacture thereof
AU2001223396A1 (en) * 2000-02-01 2001-08-14 Disetronic Licensing Ag Container and device for administering a substance
US6264987B1 (en) * 2000-05-19 2001-07-24 Alkermes Controlled Therapeutics Inc. Ii Method for preparing microparticles having a selected polymer molecular weight
US6495164B1 (en) * 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
DK1404331T3 (da) 2001-07-06 2008-01-28 Penwest Pharmaceuticals Co Sustained release-formuleringer af oxymorphon
KR20030034171A (ko) * 2001-07-06 2003-05-01 엔도 파마슈티걸즈, 인크. 옥시모르폰 제어 방출 제형
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US6972291B2 (en) * 2002-07-02 2005-12-06 Bernstein Richard K Method for reducing food intake
US7842377B2 (en) * 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7449236B2 (en) 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
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US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7588825B2 (en) 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
EP1610674A4 (en) * 2003-03-13 2008-05-21 Cheryl M Burgess METHODS OF ADMINISTERING MATERIAL TO PATIENT TO OBTAIN DERMAL IMPROVEMENT
JP2007526217A (ja) * 2003-06-04 2007-09-13 アルカーメス，インコーポレイテッド ナルトレキソンの多型形態
US6987111B2 (en) 2003-08-06 2006-01-17 Alkermes Controlled Therapeutics, Ii Aripiprazole, olanzapine and haloperidol pamoate salts
US20050031713A1 (en) * 2003-08-06 2005-02-10 Elliot Ehrich Methods for administering active agents to CYP3A4 sensitive patients
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
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US7901770B2 (en) 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
EP1718258B1 (en) * 2004-02-23 2009-03-25 Euro-Celtique S.A. Abuse resistance opioid transdermal delivery device
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US20050245461A1 (en) * 2004-03-19 2005-11-03 Elliot Ehrich Methods for treating alcoholism
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7919499B2 (en) * 2004-04-22 2011-04-05 Alkermes, Inc. Naltrexone long acting formulations and methods of use
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
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US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
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CN1872063B (zh) * 2005-06-03 2011-01-26 中国人民解放军军事医学科学院毒物药物研究所 纳美芬或其盐的长效注射用微球或组合物及其制备方法
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EP1810714A1 (de) * 2006-01-19 2007-07-25 Holger Lars Hermann Verwendung einer Kombination von Heroin und Naloxon zur Drogensubstitution
RU2310449C1 (ru) * 2006-05-17 2007-11-20 Руслан Геннадьевич Нервалев Способ лечения опиоидной и/или алкогольной зависимости
CA2702680A1 (en) * 2007-10-18 2009-04-23 Aiko Biotechnology Combination analgesic employing opioid and neutral antagonist
US8748448B2 (en) 2007-10-18 2014-06-10 Aiko Biotechnology Combination analgesic employing opioid agonist and neutral antagonist
EP2219612A4 (en) 2007-12-17 2013-10-30 Paladin Labs Inc FORMULATION WITH TAXED RELEASE AND ABUSE PROTECTION
US8486449B2 (en) 2008-12-16 2013-07-16 Paladin Labs Inc. Misuse preventative, controlled release formulation
US20100196436A1 (en) * 2009-01-30 2010-08-05 Gooberman Lance L Implants containing disulfiram and an anti-inflammatory agent
US8791093B2 (en) * 2009-05-29 2014-07-29 Lance L. Gooberman Pharmaceutical delivery systems for treatment of substance abuse and other addictions
EP2544667B1 (en) * 2010-03-09 2018-11-14 Alkermes Pharma Ireland Limited Alcohol resistant enteric pharmaceutical compositions
RU2476209C1 (ru) * 2012-02-29 2013-02-27 Станислав Анатольевич Кедик Имплантируемое лекарственное средство на основе налтрексона для лечения пациентов, зависимых от алкоголя или опиатов
US20160175313A1 (en) 2013-08-06 2016-06-23 Dongkook Pharmaceutical Co., Ltd., Entecavir microspheres and pharmaceutical composition for parenteral administration containing same
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CA3208374A1 (en) * 2021-03-09 2022-09-15 Ju Hee Kim Sustained formulation for prevention or treatment of autoimmune disease containing naltrexone and method using same
WO2023090922A1 (ko) * 2021-11-18 2023-05-25 (주)인벤티지랩 날트렉손을 포함하는 서방성 주사용 조성물 및 이의 제조 방법

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Also Published As

Publication number Publication date
CN1210031C (zh) 2005-07-13
PL350548A1 (en) 2002-12-16
PT1171132E (pt) 2004-07-30
HK1047245B (zh) 2006-03-03
JP2010031036A (ja) 2010-02-12
DK1171132T3 (da) 2004-07-12
KR20020011975A (ko) 2002-02-09
NO20014896L (no) 2001-12-07
EP1171132B1 (en) 2004-03-31
KR100621261B1 (ko) 2006-09-13
CN1354664A (zh) 2002-06-19
UA79921C2 (en) 2007-08-10
ES2218147T3 (es) 2004-11-16
JP2002541202A (ja) 2002-12-03
EA200101062A1 (ru) 2002-04-25
CA2369302A1 (en) 2000-10-19
EA004734B1 (ru) 2004-08-26
AU780852B2 (en) 2005-04-21
WO2000061147A1 (en) 2000-10-19
ATE262906T1 (de) 2004-04-15
NO20014896D0 (no) 2001-10-08
AU4220300A (en) 2000-11-14
CZ20013636A3 (cs) 2002-03-13
NZ515359A (en) 2002-10-25
NO328647B1 (no) 2010-04-19
BR0009639A (pt) 2002-02-05
US6306425B1 (en) 2001-10-23
TR200102880T2 (tr) 2002-03-21
MXPA01010185A (es) 2003-07-21
DE60009477T2 (de) 2005-02-24
PL196930B1 (pl) 2008-02-29
HUP0200838A2 (hu) 2002-07-29
CA2369302C (en) 2007-09-25
EP1171132A1 (en) 2002-01-16
HK1047245A1 (en) 2003-02-14
IL145802A (en) 2009-02-11
JP4995371B2 (ja) 2012-08-08
DE60009477D1 (de) 2004-05-06
HUP0200838A3 (en) 2005-07-28

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