UA61897C2 - Protein kinase c inhibitors, methods for synthesis, pharmaceutical formulations and methods for treating microvascular diabetic complications - Google Patents
Protein kinase c inhibitors, methods for synthesis, pharmaceutical formulations and methods for treating microvascular diabetic complications Download PDFInfo
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- UA61897C2 UA61897C2 UA98052515A UA98052515A UA61897C2 UA 61897 C2 UA61897 C2 UA 61897C2 UA 98052515 A UA98052515 A UA 98052515A UA 98052515 A UA98052515 A UA 98052515A UA 61897 C2 UA61897 C2 UA 61897C2
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- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
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- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US697095P | 1995-11-20 | 1995-11-20 | |
| PCT/US1996/018512 WO1997018809A1 (fr) | 1995-11-20 | 1996-11-18 | Inhibiteur de la proteine kinase c |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA61897C2 true UA61897C2 (en) | 2003-12-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA98052515A UA61897C2 (en) | 1995-11-20 | 1996-11-18 | Protein kinase c inhibitors, methods for synthesis, pharmaceutical formulations and methods for treating microvascular diabetic complications |
Country Status (34)
| Country | Link |
|---|---|
| US (3) | US5710145A (fr) |
| EP (1) | EP0776895B1 (fr) |
| JP (1) | JP3348859B2 (fr) |
| KR (1) | KR100304210B1 (fr) |
| CN (1) | CN1093759C (fr) |
| AR (2) | AR004717A1 (fr) |
| AT (1) | ATE172199T1 (fr) |
| AU (1) | AU711125B2 (fr) |
| BR (1) | BR9611724A (fr) |
| CA (1) | CA2237221C (fr) |
| CO (1) | CO4750823A1 (fr) |
| CY (1) | CY2103B1 (fr) |
| CZ (1) | CZ297524B6 (fr) |
| DE (1) | DE69600784T2 (fr) |
| DK (1) | DK0776895T3 (fr) |
| EA (1) | EA000967B1 (fr) |
| EG (1) | EG23871A (fr) |
| ES (1) | ES2122764T3 (fr) |
| HU (1) | HU226821B1 (fr) |
| IL (1) | IL124417A (fr) |
| MX (1) | MX9803792A (fr) |
| MY (1) | MY118068A (fr) |
| NO (1) | NO310196B1 (fr) |
| NZ (1) | NZ323571A (fr) |
| PE (1) | PE22798A1 (fr) |
| PL (1) | PL184715B1 (fr) |
| RO (1) | RO120074B1 (fr) |
| SI (1) | SI0776895T1 (fr) |
| TR (1) | TR199800759T2 (fr) |
| TW (1) | TW403754B (fr) |
| UA (1) | UA61897C2 (fr) |
| WO (1) | WO1997018809A1 (fr) |
| YU (1) | YU49315B (fr) |
| ZA (1) | ZA969646B (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2485951C2 (ru) * | 2007-12-21 | 2013-06-27 | Новартис Аг | Фармацевтическая композиция |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5624949A (en) * | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
| US6093740A (en) * | 1997-04-30 | 2000-07-25 | Eli Lilly And Company | Therapeutic treatment for skin disorders |
| AR017200A1 (es) | 1997-12-23 | 2001-08-22 | Astrazeneca Ab | Compuestos inhibidores de la proteina cinasa c, sales farmaceuticamente aceptables de los mismos, formulaciones farmaceuitcas que los comprenden, usode las mismas y proceso para la sintesis de dichos compuestos |
| US6620977B1 (en) | 1998-01-30 | 2003-09-16 | Daiso Co., Ltd. | Process for producing butanetriol derivative |
| US6291446B1 (en) | 1998-03-05 | 2001-09-18 | Eli Lilly And Company | Therapeutic treatment for cytomegalovirus infection |
| US6225301B1 (en) | 1998-03-05 | 2001-05-01 | Eli Lilly And Company | Therapeutic treatment for renal dysfunction |
| US6103713A (en) * | 1998-03-05 | 2000-08-15 | Eli Lilly And Company | Therapeutic treatment for autoimmune diseases |
| US6103712A (en) * | 1998-03-05 | 2000-08-15 | Eli Lilly And Company | Therapeutic treatment for asthma |
| AU758241B2 (en) * | 1998-03-13 | 2003-03-20 | University Of British Columbia, The | Granulatimide derivatives for use in cancer treatment |
| SE9800835D0 (sv) | 1998-03-13 | 1998-03-13 | Astra Ab | New Compounds |
| CA2245029A1 (fr) | 1998-03-13 | 1999-09-13 | University Of British Columbia | Composes granulatimide en tant qu'inhibiteurs de controle g2 |
| US6706721B1 (en) | 1998-04-29 | 2004-03-16 | Osi Pharmaceuticals, Inc. | N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate |
| US6127401A (en) | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
| TWI223598B (en) * | 1998-06-22 | 2004-11-11 | Pfizer Ireland Pharmaceuticals | An intranasal pharmaceutical composition for the treatment of male erectile dysfunction or female sexual disorders, an intranasal delivery system or device and sildenafil mesylate |
| GB9828640D0 (en) * | 1998-12-23 | 1999-02-17 | Smithkline Beecham Plc | Novel method and compounds |
| US6841567B1 (en) * | 1999-02-12 | 2005-01-11 | Cephalon, Inc. | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
| US6492406B1 (en) | 1999-05-21 | 2002-12-10 | Astrazeneca Ab | Pharmaceutically active compounds |
| US6284783B1 (en) | 1999-06-09 | 2001-09-04 | The Uab Research Foundation | Use of bisindolylmaleimide compounds to induce Fas-mediated apoptosis |
| US6399780B1 (en) | 1999-08-20 | 2002-06-04 | Cephalon, Inc. | Isomeric fused pyrrolocarbazoles and isoindolones |
| UA74803C2 (uk) | 1999-11-11 | 2006-02-15 | Осі Фармасьютікалз, Інк. | Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування |
| US7087613B2 (en) * | 1999-11-11 | 2006-08-08 | Osi Pharmaceuticals, Inc. | Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride |
| US6852688B2 (en) | 2000-03-10 | 2005-02-08 | University Of Florida | Compositions for treating diabetic retinopathy and methods of using same |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2485951C2 (ru) * | 2007-12-21 | 2013-06-27 | Новартис Аг | Фармацевтическая композиция |
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