UA110790C2 - Спосіб передбачування рецидиву раку молочної залози при ендокринному лікуванні - Google Patents

Спосіб передбачування рецидиву раку молочної залози при ендокринному лікуванні

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Publication number
UA110790C2
UA110790C2 UAA201212456A UAA201212456A UA110790C2 UA 110790 C2 UA110790 C2 UA 110790C2 UA A201212456 A UAA201212456 A UA A201212456A UA A201212456 A UAA201212456 A UA A201212456A UA 110790 C2 UA110790 C2 UA 110790C2
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breast cancer
cancer recurrence
endocrine treatment
prediction under
recurrence prediction
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UAA201212456A
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English (en)
Russian (ru)
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Марайке ДАРТМАНН
Інке Сабін Федер
Матіас Германн
Гідо Хенніг
Карстен Вебер
Тьорн Крістіан фон
Ральф КРОНЕНВЕТТ
Крістоф Петри
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Сівідон Діагностікс Гмбх
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Publication of UA110790C2 publication Critical patent/UA110790C2/uk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
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  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
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  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Винахід належить до способу, набору для прогнозування наслідків захворювання при раку молочної залози, причому вказаний спосіб включає: (a) визначення в зразку пухлини від вказаного пацієнта рівнів експресії РНК наступних 8 генів: UBE2C, BIRC5, DHCR7, STC2, AZGP1, RBBP8, IL6ST і MGP; (b) математичне комбінування величин рівня експресії для генів вказаного набору, причому ці величини визначають в зразку пухлини з одержанням комбінованого показника, де вказаний комбінований показник указує на прогноз у вказаного пацієнта.
UAA201212456A 2010-03-31 2011-03-29 Спосіб передбачування рецидиву раку молочної залози при ендокринному лікуванні UA110790C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10158561 2010-03-31
PCT/EP2011/054855 WO2011120984A1 (en) 2010-03-31 2011-03-29 Method for breast cancer recurrence prediction under endocrine treatment

Publications (1)

Publication Number Publication Date
UA110790C2 true UA110790C2 (uk) 2016-02-25

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US (4) US20130065786A1 (uk)
EP (2) EP2845911B1 (uk)
JP (2) JP5940517B2 (uk)
KR (1) KR101864855B1 (uk)
CN (2) CN102971435B (uk)
BR (2) BR122020016370B1 (uk)
CA (1) CA2793133C (uk)
ES (2) ES2525382T3 (uk)
HK (1) HK1181817A1 (uk)
HU (1) HUE030164T2 (uk)
MX (1) MX2012011167A (uk)
PL (2) PL2553118T3 (uk)
PT (2) PT2845911T (uk)
RU (1) RU2654587C2 (uk)
UA (1) UA110790C2 (uk)
WO (1) WO2011120984A1 (uk)
ZA (1) ZA201207229B (uk)

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HUE030164T2 (en) 2017-05-29
RU2654587C2 (ru) 2018-05-21
JP2016189781A (ja) 2016-11-10
CN102971435B (zh) 2016-05-11
US20170067118A1 (en) 2017-03-09
ES2525382T3 (es) 2014-12-23
ZA201207229B (en) 2013-06-26
CN105821125A (zh) 2016-08-03
EP2845911A1 (en) 2015-03-11
EP2845911B1 (en) 2016-05-18
PT2845911T (pt) 2016-08-25
ES2587591T3 (es) 2016-10-25
PL2845911T3 (pl) 2017-01-31
AU2011234573B2 (en) 2015-10-01
US10851427B2 (en) 2020-12-01
PL2553118T3 (pl) 2015-03-31
EP2553118A1 (en) 2013-02-06
US20200224281A1 (en) 2020-07-16
CA2793133C (en) 2019-08-20
US10577661B2 (en) 2020-03-03
CA2793133A1 (en) 2011-10-06
KR20130010048A (ko) 2013-01-24
BR112012024718A2 (pt) 2017-01-10
JP2013523105A (ja) 2013-06-17
EP2553118B1 (en) 2014-10-15
US20130065786A1 (en) 2013-03-14
KR101864855B1 (ko) 2018-07-13
HK1181817A1 (en) 2013-11-15
JP5940517B2 (ja) 2016-06-29
MX2012011167A (es) 2013-02-07
US20210123107A1 (en) 2021-04-29
CN102971435A (zh) 2013-03-13
BR122020016370B1 (pt) 2021-05-11
AU2011234573A1 (en) 2012-09-20
PT2553118E (pt) 2014-12-17
WO2011120984A1 (en) 2011-10-06
RU2012146343A (ru) 2014-05-10
US11913078B2 (en) 2024-02-27

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