UA110717C2 - Аналог акулячого хондроїтинсульфату і спосіб його одержання - Google Patents
Аналог акулячого хондроїтинсульфату і спосіб його одержанняInfo
- Publication number
- UA110717C2 UA110717C2 UAA201313498A UAA201313498A UA110717C2 UA 110717 C2 UA110717 C2 UA 110717C2 UA A201313498 A UAA201313498 A UA A201313498A UA A201313498 A UAA201313498 A UA A201313498A UA 110717 C2 UA110717 C2 UA 110717C2
- Authority
- UA
- Ukraine
- Prior art keywords
- shark
- pharmaceuticals
- biological activity
- hondroyitynsulfatu
- analog
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Polymers & Plastics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Steroid Compounds (AREA)
Abstract
Винахід належить до медицини та хіміко-фармацевтичної промисловості, зокрема до створення, виробництва та застосування засобу, що є аналогом хондроїтинсульфату, одержаного з акулячого хряща, який, при дуже малій кількості 4-сульфату, показує високий рівень щільності заряду і біологічної активності, які можна порівняти з природними хондроїтинсульфатами; винахід належить також до способу одержання зазначеного аналога хондроїтинсульфату, одержаного з акулячого хряща. Біологічна активність і протизапальні властивості, продемонстровані запропонованим ХС in vitro, роблять його порівнянним до природних препаратів і, відтак, потенціально прийнятним для використання як лікарського засобу у фармацевтичних препаратах і нутрицевтиках.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2011/058297 WO2012159655A1 (en) | 2011-05-20 | 2011-05-20 | Shark-like chondroitin sulphate and process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA110717C2 true UA110717C2 (uk) | 2016-02-10 |
Family
ID=44626453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201313498A UA110717C2 (uk) | 2011-05-20 | 2011-05-20 | Аналог акулячого хондроїтинсульфату і спосіб його одержання |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP2710043B1 (uk) |
| JP (1) | JP5770367B2 (uk) |
| KR (1) | KR101788536B1 (uk) |
| CN (1) | CN103635491B (uk) |
| AU (1) | AU2011369262B2 (uk) |
| BR (1) | BR112013029765B1 (uk) |
| CA (1) | CA2835691C (uk) |
| CY (1) | CY1117567T1 (uk) |
| DK (1) | DK2710043T3 (uk) |
| EA (1) | EA023370B1 (uk) |
| ES (1) | ES2584038T3 (uk) |
| HR (1) | HRP20160673T1 (uk) |
| HU (1) | HUE030096T2 (uk) |
| IL (1) | IL229432A (uk) |
| MX (1) | MX346787B (uk) |
| NZ (1) | NZ617808A (uk) |
| PL (1) | PL2710043T3 (uk) |
| PT (1) | PT2710043T (uk) |
| RS (1) | RS54854B1 (uk) |
| SG (1) | SG194936A1 (uk) |
| SI (1) | SI2710043T1 (uk) |
| UA (1) | UA110717C2 (uk) |
| WO (1) | WO2012159655A1 (uk) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20120896A1 (it) * | 2012-05-23 | 2013-11-24 | Bongulielmi Reto | Condroitina per uso in medicina |
| ITMI20130117A1 (it) | 2013-01-25 | 2014-07-26 | Gnosis Spa | Composizioni comprendenti condroitin solfato, enzimi proteolitici e composti sulfidrilati capaci di migliorare la biodisponibilita' del condroitin solfato |
| CN104877042B (zh) * | 2015-06-10 | 2017-08-29 | 浙江三门恒康制药有限公司 | 一种类肝素的制备方法 |
| IT202000004564A1 (it) | 2020-03-04 | 2021-09-04 | Lesaffre & Cie | Processo per la solfatazione diretta di polisaccaridi in solvente ecologicamente accettabile |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2538404B1 (uk) * | 1982-12-28 | 1985-08-23 | Anic Spa | |
| JP3497209B2 (ja) * | 1993-08-24 | 2004-02-16 | 生化学工業株式会社 | 硫酸化糖の脱硫酸化方法 |
| US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
| IT1289613B1 (it) * | 1997-02-07 | 1998-10-15 | Inalco Spa | Polisaccaridi batterici o-solfatati |
| ITMI20012200A1 (it) * | 2001-10-22 | 2003-04-22 | Ibsa Inst Biochimique Sa | Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti |
| EP1950308A4 (en) | 2005-11-17 | 2009-11-11 | Seikagaku Kogyo Co Ltd | PROCESS FOR PRODUCING CHONDROITIN |
| US8067204B2 (en) | 2005-12-15 | 2011-11-29 | Seikagaku Corporation | Long-chain chondroitin sugar chain and method for producing the same and method for promoting synthesis of chondroitin |
| JP5622346B2 (ja) * | 2006-05-19 | 2014-11-12 | 愛知県 | 神経細胞の細胞死抑制剤等 |
| US8283145B2 (en) * | 2007-04-24 | 2012-10-09 | Seikagaku Corporation | Chondroitin-producing bacterium and method of producing chondroitin |
| JP2010215508A (ja) * | 2007-06-25 | 2010-09-30 | Pg Research:Kk | 骨形成タンパク質活性調節剤 |
| WO2009149155A1 (en) | 2008-06-04 | 2009-12-10 | Amano Enzyme Usa., Ltd. | Microbial-derived chondroitin sulfate |
| IT1394311B1 (it) * | 2009-05-25 | 2012-06-06 | Altergon Sa | Produzione biotecnologica di condroitina |
-
2011
- 2011-05-20 RS RS20160428A patent/RS54854B1/sr unknown
- 2011-05-20 EA EA201391734A patent/EA023370B1/ru not_active IP Right Cessation
- 2011-05-20 JP JP2014510673A patent/JP5770367B2/ja active Active
- 2011-05-20 MX MX2013013325A patent/MX346787B/es active IP Right Grant
- 2011-05-20 DK DK11720309.1T patent/DK2710043T3/en active
- 2011-05-20 UA UAA201313498A patent/UA110717C2/uk unknown
- 2011-05-20 PL PL11720309.1T patent/PL2710043T3/pl unknown
- 2011-05-20 EP EP11720309.1A patent/EP2710043B1/en active Active
- 2011-05-20 PT PT117203091T patent/PT2710043T/pt unknown
- 2011-05-20 WO PCT/EP2011/058297 patent/WO2012159655A1/en active Application Filing
- 2011-05-20 CN CN201180071901.4A patent/CN103635491B/zh active Active
- 2011-05-20 ES ES11720309.1T patent/ES2584038T3/es active Active
- 2011-05-20 BR BR112013029765-4A patent/BR112013029765B1/pt active IP Right Grant
- 2011-05-20 AU AU2011369262A patent/AU2011369262B2/en active Active
- 2011-05-20 KR KR1020137033869A patent/KR101788536B1/ko active IP Right Grant
- 2011-05-20 SI SI201130899A patent/SI2710043T1/sl unknown
- 2011-05-20 NZ NZ617808A patent/NZ617808A/en unknown
- 2011-05-20 SG SG2013084033A patent/SG194936A1/en unknown
- 2011-05-20 HU HUE11720309A patent/HUE030096T2/en unknown
- 2011-05-20 CA CA2835691A patent/CA2835691C/en active Active
-
2013
- 2013-11-14 IL IL229432A patent/IL229432A/en active IP Right Grant
-
2016
- 2016-05-24 CY CY20161100456T patent/CY1117567T1/el unknown
- 2016-06-14 HR HRP20160673TT patent/HRP20160673T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2835691C (en) | 2018-08-21 |
| DK2710043T3 (en) | 2016-08-22 |
| MX346787B (es) | 2017-03-31 |
| NZ617808A (en) | 2015-06-26 |
| MX2013013325A (es) | 2014-02-27 |
| IL229432A (en) | 2017-09-28 |
| IL229432A0 (en) | 2014-01-30 |
| JP2014513742A (ja) | 2014-06-05 |
| HRP20160673T1 (hr) | 2016-07-01 |
| PL2710043T3 (pl) | 2016-11-30 |
| CA2835691A1 (en) | 2012-11-29 |
| SG194936A1 (en) | 2013-12-30 |
| AU2011369262B2 (en) | 2017-02-02 |
| KR20140044826A (ko) | 2014-04-15 |
| EA201391734A1 (ru) | 2014-03-31 |
| BR112013029765B1 (pt) | 2021-02-17 |
| PT2710043T (pt) | 2016-07-14 |
| SI2710043T1 (sl) | 2016-08-31 |
| EA023370B1 (ru) | 2016-05-31 |
| EP2710043B1 (en) | 2016-05-11 |
| CY1117567T1 (el) | 2017-04-26 |
| EP2710043A1 (en) | 2014-03-26 |
| HUE030096T2 (en) | 2017-04-28 |
| CN103635491A (zh) | 2014-03-12 |
| CN103635491B (zh) | 2016-05-11 |
| KR101788536B1 (ko) | 2017-10-20 |
| ES2584038T3 (es) | 2016-09-23 |
| BR112013029765A2 (pt) | 2017-01-17 |
| WO2012159655A1 (en) | 2012-11-29 |
| AU2011369262A1 (en) | 2013-11-28 |
| JP5770367B2 (ja) | 2015-08-26 |
| RS54854B1 (sr) | 2016-10-31 |
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