UA110717C2 - Аналог акулячого хондроїтинсульфату і спосіб його одержання - Google Patents

Аналог акулячого хондроїтинсульфату і спосіб його одержання

Info

Publication number
UA110717C2
UA110717C2 UAA201313498A UAA201313498A UA110717C2 UA 110717 C2 UA110717 C2 UA 110717C2 UA A201313498 A UAA201313498 A UA A201313498A UA A201313498 A UAA201313498 A UA A201313498A UA 110717 C2 UA110717 C2 UA 110717C2
Authority
UA
Ukraine
Prior art keywords
shark
pharmaceuticals
biological activity
hondroyitynsulfatu
analog
Prior art date
Application number
UAA201313498A
Other languages
English (en)
Inventor
Ерманно Велоті
Нікколо Мірагліа
Девід Б'янчі
Марко Валетті
Паола Базза
Original Assignee
ГНОЗІС С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ГНОЗІС С.п.А. filed Critical ГНОЗІС С.п.А.
Publication of UA110717C2 publication Critical patent/UA110717C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Steroid Compounds (AREA)

Abstract

Винахід належить до медицини та хіміко-фармацевтичної промисловості, зокрема до створення, виробництва та застосування засобу, що є аналогом хондроїтинсульфату, одержаного з акулячого хряща, який, при дуже малій кількості 4-сульфату, показує високий рівень щільності заряду і біологічної активності, які можна порівняти з природними хондроїтинсульфатами; винахід належить також до способу одержання зазначеного аналога хондроїтинсульфату, одержаного з акулячого хряща. Біологічна активність і протизапальні властивості, продемонстровані запропонованим ХС in vitro, роблять його порівнянним до природних препаратів і, відтак, потенціально прийнятним для використання як лікарського засобу у фармацевтичних препаратах і нутрицевтиках.
UAA201313498A 2011-05-20 2011-05-20 Аналог акулячого хондроїтинсульфату і спосіб його одержання UA110717C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2011/058297 WO2012159655A1 (en) 2011-05-20 2011-05-20 Shark-like chondroitin sulphate and process for the preparation thereof

Publications (1)

Publication Number Publication Date
UA110717C2 true UA110717C2 (uk) 2016-02-10

Family

ID=44626453

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201313498A UA110717C2 (uk) 2011-05-20 2011-05-20 Аналог акулячого хондроїтинсульфату і спосіб його одержання

Country Status (23)

Country Link
EP (1) EP2710043B1 (uk)
JP (1) JP5770367B2 (uk)
KR (1) KR101788536B1 (uk)
CN (1) CN103635491B (uk)
AU (1) AU2011369262B2 (uk)
BR (1) BR112013029765B1 (uk)
CA (1) CA2835691C (uk)
CY (1) CY1117567T1 (uk)
DK (1) DK2710043T3 (uk)
EA (1) EA023370B1 (uk)
ES (1) ES2584038T3 (uk)
HR (1) HRP20160673T1 (uk)
HU (1) HUE030096T2 (uk)
IL (1) IL229432A (uk)
MX (1) MX346787B (uk)
NZ (1) NZ617808A (uk)
PL (1) PL2710043T3 (uk)
PT (1) PT2710043T (uk)
RS (1) RS54854B1 (uk)
SG (1) SG194936A1 (uk)
SI (1) SI2710043T1 (uk)
UA (1) UA110717C2 (uk)
WO (1) WO2012159655A1 (uk)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20120896A1 (it) * 2012-05-23 2013-11-24 Bongulielmi Reto Condroitina per uso in medicina
ITMI20130117A1 (it) 2013-01-25 2014-07-26 Gnosis Spa Composizioni comprendenti condroitin solfato, enzimi proteolitici e composti sulfidrilati capaci di migliorare la biodisponibilita' del condroitin solfato
CN104877042B (zh) * 2015-06-10 2017-08-29 浙江三门恒康制药有限公司 一种类肝素的制备方法
IT202000004564A1 (it) 2020-03-04 2021-09-04 Lesaffre & Cie Processo per la solfatazione diretta di polisaccaridi in solvente ecologicamente accettabile

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2538404B1 (uk) * 1982-12-28 1985-08-23 Anic Spa
JP3497209B2 (ja) * 1993-08-24 2004-02-16 生化学工業株式会社 硫酸化糖の脱硫酸化方法
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
IT1289613B1 (it) * 1997-02-07 1998-10-15 Inalco Spa Polisaccaridi batterici o-solfatati
ITMI20012200A1 (it) * 2001-10-22 2003-04-22 Ibsa Inst Biochimique Sa Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti
US20090233336A1 (en) 2005-11-17 2009-09-17 Seikagaku Corporation Process for producing chondroitin
JP5081629B2 (ja) 2005-12-15 2012-11-28 生化学工業株式会社 長鎖コンドロイチン糖鎖及びその製造方法並びにコンドロイチン合成の促進方法
JP5622346B2 (ja) * 2006-05-19 2014-11-12 愛知県 神経細胞の細胞死抑制剤等
US8283145B2 (en) * 2007-04-24 2012-10-09 Seikagaku Corporation Chondroitin-producing bacterium and method of producing chondroitin
JP2010215508A (ja) * 2007-06-25 2010-09-30 Pg Research:Kk 骨形成タンパク質活性調節剤
US9109243B2 (en) 2008-06-04 2015-08-18 Amano Enzyme Usa, Ltd. Microbial-derived chondroitin sulfate
IT1394311B1 (it) * 2009-05-25 2012-06-06 Altergon Sa Produzione biotecnologica di condroitina

Also Published As

Publication number Publication date
CY1117567T1 (el) 2017-04-26
CN103635491B (zh) 2016-05-11
SG194936A1 (en) 2013-12-30
IL229432A0 (en) 2014-01-30
BR112013029765B1 (pt) 2021-02-17
CA2835691A1 (en) 2012-11-29
CA2835691C (en) 2018-08-21
WO2012159655A1 (en) 2012-11-29
IL229432A (en) 2017-09-28
JP2014513742A (ja) 2014-06-05
ES2584038T3 (es) 2016-09-23
CN103635491A (zh) 2014-03-12
EA201391734A1 (ru) 2014-03-31
KR20140044826A (ko) 2014-04-15
PL2710043T3 (pl) 2016-11-30
EP2710043B1 (en) 2016-05-11
MX2013013325A (es) 2014-02-27
PT2710043T (pt) 2016-07-14
EA023370B1 (ru) 2016-05-31
EP2710043A1 (en) 2014-03-26
AU2011369262A1 (en) 2013-11-28
AU2011369262B2 (en) 2017-02-02
HRP20160673T1 (hr) 2016-07-01
DK2710043T3 (en) 2016-08-22
KR101788536B1 (ko) 2017-10-20
BR112013029765A2 (pt) 2017-01-17
MX346787B (es) 2017-03-31
HUE030096T2 (en) 2017-04-28
RS54854B1 (sr) 2016-10-31
SI2710043T1 (sl) 2016-08-31
JP5770367B2 (ja) 2015-08-26
NZ617808A (en) 2015-06-26

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