BR112014026308A2 - composições de cultura celular e métodos para produção de polipeptídeos - Google Patents

composições de cultura celular e métodos para produção de polipeptídeos

Info

Publication number
BR112014026308A2
BR112014026308A2 BR112014026308A BR112014026308A BR112014026308A2 BR 112014026308 A2 BR112014026308 A2 BR 112014026308A2 BR 112014026308 A BR112014026308 A BR 112014026308A BR 112014026308 A BR112014026308 A BR 112014026308A BR 112014026308 A2 BR112014026308 A2 BR 112014026308A2
Authority
BR
Brazil
Prior art keywords
cell culture
methods
compositions
media
polypeptides
Prior art date
Application number
BR112014026308A
Other languages
English (en)
Other versions
BR112014026308A8 (pt
Inventor
Zhang Boyan
Gawlitzek Martin
S Mun Melissa
Vijayasankaran Natarajan
Varma Sharat
R Arevalo Silvana
J Meier Steven
Carvalhal Veronica
Yang Yi
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49380652&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014026308(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112014026308A2 publication Critical patent/BR112014026308A2/pt
Publication of BR112014026308A8 publication Critical patent/BR112014026308A8/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/005Protein-free medium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

abstract cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. compositions comprising polypeptides produced by the methods are also provided. tradução do resumo resumo patente de invenção: “composições de cultura celular e métodos para produção de polipeptídeos”. a presente invenção se refere a meios de cultura celular, tais como meios de cultura celular quimicamente definidos, assim como se refere a métodos de utilização dos meios para crescimento celular (isto é, cultura celular) e produção de polipeptídeos (por exemplo, anticorpos). além disso a presente invenção se refere a composições compreendendo polipeptídeos produzidos pelos métodos.
BR112014026308A 2012-04-24 2013-04-24 meios de cultura celular, seu método de cultura, polipeptídeo, seu método de produção e seu uso, composições farmacêutica, e kit BR112014026308A8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261637778P 2012-04-24 2012-04-24
US201261637780P 2012-04-24 2012-04-24
US13/841,864 US20130281355A1 (en) 2012-04-24 2013-03-15 Cell culture compositions and methods for polypeptide production
PCT/US2013/037992 WO2013163294A1 (en) 2012-04-24 2013-04-24 Cell culture compositions and methods for polypeptide production

Publications (2)

Publication Number Publication Date
BR112014026308A2 true BR112014026308A2 (pt) 2017-06-27
BR112014026308A8 BR112014026308A8 (pt) 2021-06-01

Family

ID=49380652

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014026308A BR112014026308A8 (pt) 2012-04-24 2013-04-24 meios de cultura celular, seu método de cultura, polipeptídeo, seu método de produção e seu uso, composições farmacêutica, e kit

Country Status (22)

Country Link
US (2) US20130281355A1 (pt)
EP (2) EP3533864A1 (pt)
JP (4) JP6367792B2 (pt)
KR (2) KR102115052B1 (pt)
CN (2) CN104428409A (pt)
AR (1) AR090822A1 (pt)
AU (2) AU2013251647B2 (pt)
BR (1) BR112014026308A8 (pt)
CA (1) CA2871006C (pt)
ES (1) ES2716301T3 (pt)
HK (1) HK1208496A1 (pt)
HR (1) HRP20190484T1 (pt)
IL (1) IL235235A0 (pt)
MX (2) MX363493B (pt)
MY (1) MY181513A (pt)
NZ (1) NZ701791A (pt)
PL (1) PL2841561T3 (pt)
RU (2) RU2678142C2 (pt)
SG (2) SG10201810830UA (pt)
SI (1) SI2841561T1 (pt)
WO (1) WO2013163294A1 (pt)
ZA (2) ZA201408092B (pt)

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CN108823267B (zh) * 2018-06-25 2020-05-08 深圳市菲鹏生物制药股份有限公司 调节cho-k1表达系统所分泌抗体的酸性峰含量的方法
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TW202128744A (zh) 2019-12-06 2021-08-01 美商再生元醫藥公司 抗vegf蛋白組合物及其製備方法
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JP7404929B2 (ja) 2020-02-26 2023-12-26 富士フイルムビジネスイノベーション株式会社 発光装置、光学装置及び計測装置
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Also Published As

Publication number Publication date
RU2018146497A (ru) 2019-02-04
SG11201406903SA (en) 2014-12-30
BR112014026308A8 (pt) 2021-06-01
MX363493B (es) 2019-03-26
AU2019202259A1 (en) 2019-04-18
EP2841561B1 (en) 2019-01-16
AU2013251647A1 (en) 2014-12-18
KR102115052B1 (ko) 2020-05-25
EP2841561A1 (en) 2015-03-04
US20130281355A1 (en) 2013-10-24
ES2716301T3 (es) 2019-06-11
RU2014147018A (ru) 2016-06-10
SI2841561T1 (sl) 2019-04-30
AU2019202259B2 (en) 2021-11-11
EP3533864A1 (en) 2019-09-04
CA2871006C (en) 2021-05-25
PL2841561T3 (pl) 2019-05-31
JP6367792B2 (ja) 2018-08-01
CN111440758A (zh) 2020-07-24
ZA201707452B (en) 2021-03-31
AR090822A1 (es) 2014-12-10
SG10201810830UA (en) 2018-12-28
IL235235A0 (en) 2014-12-31
WO2013163294A1 (en) 2013-10-31
HRP20190484T1 (hr) 2019-05-17
JP2023156371A (ja) 2023-10-24
ZA201408092B (en) 2019-03-27
MY181513A (en) 2020-12-24
HK1208496A1 (en) 2016-03-04
JP2015515281A (ja) 2015-05-28
KR20200057795A (ko) 2020-05-26
MX2014012838A (es) 2015-10-22
RU2678142C2 (ru) 2019-01-23
AU2013251647B2 (en) 2019-04-04
JP2021104023A (ja) 2021-07-26
CN104428409A (zh) 2015-03-18
MX2019003427A (es) 2020-11-12
KR102339106B1 (ko) 2021-12-15
US20240093143A1 (en) 2024-03-21
JP7323272B2 (ja) 2023-08-08
KR20150003351A (ko) 2015-01-08
CA2871006A1 (en) 2013-10-31
JP2018183154A (ja) 2018-11-22
NZ701791A (en) 2017-03-31

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.