EA201300884A1 - Способ получения нового антибактериального лекарственного средства на основе рекомбинантного полипептида - Google Patents

Способ получения нового антибактериального лекарственного средства на основе рекомбинантного полипептида

Info

Publication number
EA201300884A1
EA201300884A1 EA201300884A EA201300884A EA201300884A1 EA 201300884 A1 EA201300884 A1 EA 201300884A1 EA 201300884 A EA201300884 A EA 201300884A EA 201300884 A EA201300884 A EA 201300884A EA 201300884 A1 EA201300884 A1 EA 201300884A1
Authority
EA
Eurasian Patent Office
Prior art keywords
recombinant
polypepe
obtaining
basis
new anti
Prior art date
Application number
EA201300884A
Other languages
English (en)
Other versions
EA201300884A8 (ru
EA030794B1 (ru
Inventor
Хиаокуинг Киу
Ронгкюи Ли
Хиангли Зханг
Хианген Зханг
Донгкин Ванг
Original Assignee
Бэйджинг Креатед Трибиотехнолэджи Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бэйджинг Креатед Трибиотехнолэджи Ко., Лтд. filed Critical Бэйджинг Креатед Трибиотехнолэджи Ко., Лтд.
Publication of EA201300884A1 publication Critical patent/EA201300884A1/ru
Publication of EA201300884A8 publication Critical patent/EA201300884A8/ru
Publication of EA030794B1 publication Critical patent/EA030794B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение предусматривает способ получения нового антибактериального лекарственного средства на основе рекомбинантного полипептида, который относится преимущественно к составу жидкой культуральной среды, пригодной для крупномасштабного производства антибактериального полипептида, а также оптимизации параметров масштабированной культуры.
EA201300884A 2011-03-04 2012-03-01 Жидкая питательная среда и способ крупномасштабного производства антибактериального слитого полипептида колицина и феромона EA030794B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110052238.5A CN102653779B (zh) 2011-03-04 2011-03-04 一种新型重组抗菌多肽药物的制备方法
PCT/CN2012/071825 WO2012119524A1 (zh) 2011-03-04 2012-03-01 一种新型重组抗菌多肽药物的制备方法

Publications (3)

Publication Number Publication Date
EA201300884A1 true EA201300884A1 (ru) 2014-04-30
EA201300884A8 EA201300884A8 (ru) 2018-06-29
EA030794B1 EA030794B1 (ru) 2018-09-28

Family

ID=46729509

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201300884A EA030794B1 (ru) 2011-03-04 2012-03-01 Жидкая питательная среда и способ крупномасштабного производства антибактериального слитого полипептида колицина и феромона

Country Status (18)

Country Link
US (1) US9765378B2 (ru)
EP (1) EP2682474B1 (ru)
JP (1) JP5916769B2 (ru)
KR (1) KR101566331B1 (ru)
CN (1) CN102653779B (ru)
AP (1) AP3486A (ru)
AU (1) AU2012225088B2 (ru)
BR (1) BR112013022333A2 (ru)
CA (1) CA2828998A1 (ru)
CL (1) CL2013002534A1 (ru)
CO (1) CO6771436A2 (ru)
EA (1) EA030794B1 (ru)
HK (1) HK1169837A1 (ru)
MY (1) MY169503A (ru)
SG (1) SG193000A1 (ru)
TW (1) TWI541351B (ru)
WO (1) WO2012119524A1 (ru)
ZA (1) ZA201306575B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103131724B (zh) 2011-11-25 2015-02-25 畿晋庆三联（北京）生物技术有限公司 一种高效表达工程菌重组蛋白的方法及应用
CN105189607B (zh) * 2013-03-15 2018-06-15 建新公司 胺官能性聚酰胺
CN104328080A (zh) * 2014-08-04 2015-02-04 湖北文理学院 大肠埃希菌atcc25922增殖促进剂及其应用方法

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* Cited by examiner, † Cited by third party
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JP3737157B2 (ja) * 1994-07-11 2006-01-18 協和醗酵工業株式会社 光学活性γ−ヒドロキシ−Ｌ−グルタミン酸の製造法
RU2095409C1 (ru) * 1995-06-27 1997-11-10 Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии Способ изготовления вакцины против сибирской язвы животных
EP1210132A4 (en) * 1999-07-13 2006-03-29 Deuk Hun Ahn COMPOSITION BASED ON MEDICINAL PLANTS CONTAINED TO BE CONTAINED IN HYGIENIC ARTICLES FOR CHILDREN
RU2203948C2 (ru) * 1999-10-28 2003-05-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Штамм бактерий corynebacterium ammoniagenes - продуцент уридин-5'-монофосфата (варианты), способ получения уридин-5'- монофосфата
CN1164612C (zh) * 2001-09-11 2004-09-01 四川新泰克控股有限责任公司 人工组合的抗菌工程多肽及其制备方法
CN1412312A (zh) * 2002-08-21 2003-04-23 重庆康尔威药业股份有限公司 重组人快速骨骼肌型肌钙蛋白c在大肠杆菌中的表达及其在抗肿瘤治疗中的应用
US8212110B2 (en) * 2003-05-14 2012-07-03 Integrated Plant Genetics, Inc. Use of bacteriophage outer membrane breaching proteins expressed in plants for the control of gram-negative bacteria
AU2004267383A1 (en) * 2003-08-14 2005-03-03 The Bio Balance Corporation Bacterial strains, compositions including same and probiotic use thereof
CN100406563C (zh) * 2004-06-25 2008-07-30 私立逢甲大学 用以增进重组蛋白质的生产的核酸构建体与表达载体以及用以大量生产重组蛋白质的方法
ES2564194T3 (es) * 2005-02-09 2016-03-18 Santen Pharmaceutical Co., Ltd. Formulaciones líquidas para el tratamiento de enfermedades o dolencias
EP2035544A2 (en) * 2006-05-18 2009-03-18 Biobalance Llc Bacterial strains, compositions including same and probiotic use thereof
WO2009083756A1 (en) * 2007-12-28 2009-07-09 Roquette Freres Large scale microbial culture method
US20120149886A1 (en) * 2008-04-10 2012-06-14 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
CN101643501B (zh) * 2008-11-07 2012-06-20 畿晋庆三联（北京）生物技术有限公司 一种新型抗生素及其核苷酸序列、制备方法与应用
CN101503659B (zh) * 2009-03-11 2011-03-23 中国农业大学 一种哈茨木霉菌株及其应用
US20130295171A1 (en) * 2009-07-23 2013-11-07 U.S NUTRACEUTICALS, LLC d/b/a Valensa International Krill oil and reacted astaxanthin composition and associated method
CN101914603B (zh) * 2010-07-08 2012-11-21 暨南大学 利用乳糖诱导pMFH载体生产重组蛋白的发酵方法
CN101974548A (zh) * 2010-08-20 2011-02-16 中国农业大学 一种表达重组nisin-rbLF-N融合基因的大肠杆菌工程菌
US8563503B2 (en) * 2011-02-07 2013-10-22 Protein Design Lab. Ltd. Antibiotic, its nucleotide sequence, methods of construction and uses thereof
US8609110B2 (en) * 2011-06-21 2013-12-17 University of Pittsburgh—of the Commonwealth System of Higher Education Citrobacter freundii antibacterial agents and their use

Also Published As

Publication number Publication date
EP2682474A4 (en) 2014-12-10
EP2682474B1 (en) 2017-05-10
MY169503A (en) 2019-04-15
US20160304927A1 (en) 2016-10-20
CL2013002534A1 (es) 2014-07-11
AP3486A (en) 2015-12-31
AU2012225088B2 (en) 2015-04-09
CA2828998A1 (en) 2012-09-13
EA201300884A8 (ru) 2018-06-29
AU2012225088A1 (en) 2013-09-12
NZ614593A (en) 2015-07-31
CN102653779A (zh) 2012-09-05
AP2013007193A0 (en) 2013-10-31
WO2012119524A1 (zh) 2012-09-13
KR101566331B1 (ko) 2015-11-05
BR112013022333A2 (pt) 2016-12-06
EP2682474A1 (en) 2014-01-08
SG193000A1 (en) 2013-10-30
JP2014508766A (ja) 2014-04-10
TWI541351B (zh) 2016-07-11
US9765378B2 (en) 2017-09-19
JP5916769B2 (ja) 2016-05-11
CN102653779B (zh) 2014-02-19
EA030794B1 (ru) 2018-09-28
TW201239092A (en) 2012-10-01
HK1169837A1 (en) 2013-02-08
CO6771436A2 (es) 2013-10-15
ZA201306575B (en) 2016-03-30
KR20130138822A (ko) 2013-12-19

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU