MX2014012838A - Composiciones para cultivo celular y metodos para la produccion de polipetidos. - Google Patents
Composiciones para cultivo celular y metodos para la produccion de polipetidos.Info
- Publication number
- MX2014012838A MX2014012838A MX2014012838A MX2014012838A MX2014012838A MX 2014012838 A MX2014012838 A MX 2014012838A MX 2014012838 A MX2014012838 A MX 2014012838A MX 2014012838 A MX2014012838 A MX 2014012838A MX 2014012838 A MX2014012838 A MX 2014012838A
- Authority
- MX
- Mexico
- Prior art keywords
- cell culture
- methods
- polypeptide production
- culture compositions
- compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000006143 cell culture medium Substances 0.000 abstract 2
- 230000010261 cell growth Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se proporcionan medios de cultivo celular, tales como los medios de cultivo celular químicamente definidos, como son los métodos para utilizar los medios para el crecimiento celular (i.e. cultivo celular) y la producción de polipéptidos (e.g. anticuerpos). También se proporcionan las composiciones que comprenden los polipéptidos producidos por los métodos.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261637778P | 2012-04-24 | 2012-04-24 | |
US201261637780P | 2012-04-24 | 2012-04-24 | |
US13/841,864 US20130281355A1 (en) | 2012-04-24 | 2013-03-15 | Cell culture compositions and methods for polypeptide production |
PCT/US2013/037992 WO2013163294A1 (en) | 2012-04-24 | 2013-04-24 | Cell culture compositions and methods for polypeptide production |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014012838A true MX2014012838A (es) | 2015-10-22 |
MX363493B MX363493B (es) | 2019-03-26 |
Family
ID=49380652
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014012838A MX363493B (es) | 2012-04-24 | 2013-04-24 | Composiciones para cultivo celular y metodos para la produccion de polipetidos. |
MX2019003427A MX2019003427A (es) | 2012-04-24 | 2014-10-23 | Composiciones para cultivo celular y metodos para la produccion de polipeptidos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019003427A MX2019003427A (es) | 2012-04-24 | 2014-10-23 | Composiciones para cultivo celular y metodos para la produccion de polipeptidos. |
Country Status (22)
Country | Link |
---|---|
US (2) | US20130281355A1 (es) |
EP (2) | EP3533864A1 (es) |
JP (4) | JP6367792B2 (es) |
KR (2) | KR102115052B1 (es) |
CN (2) | CN104428409A (es) |
AR (1) | AR090822A1 (es) |
AU (2) | AU2013251647B2 (es) |
BR (1) | BR112014026308A8 (es) |
CA (1) | CA2871006C (es) |
ES (1) | ES2716301T3 (es) |
HK (1) | HK1208496A1 (es) |
HR (1) | HRP20190484T1 (es) |
IL (1) | IL235235A0 (es) |
MX (2) | MX363493B (es) |
MY (1) | MY181513A (es) |
NZ (1) | NZ701791A (es) |
PL (1) | PL2841561T3 (es) |
RU (2) | RU2678142C2 (es) |
SG (2) | SG10201810830UA (es) |
SI (1) | SI2841561T1 (es) |
WO (1) | WO2013163294A1 (es) |
ZA (2) | ZA201408092B (es) |
Families Citing this family (20)
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US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
SG10201912621TA (en) | 2013-03-15 | 2020-02-27 | Genentech Inc | Cell culture compositions with antioxidants and methods for polypeptide production |
JP2016513478A (ja) * | 2013-03-15 | 2016-05-16 | ジェネンテック, インコーポレイテッド | 細胞培養培地及び抗体を産生する方法 |
US9598667B2 (en) * | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
GB201708655D0 (en) | 2017-05-31 | 2017-07-12 | Ucb Biopharma Sprl | Cell culture methods |
US20200202051A1 (en) * | 2017-06-16 | 2020-06-25 | Ge Healthcare Bio-Sciences Ab | Method for Predicting Outcome of an Modelling of a Process in a Bioreactor |
EP3492582A1 (en) | 2017-12-01 | 2019-06-05 | UCB Biopharma SPRL | Cell culture methods |
CN108823267B (zh) * | 2018-06-25 | 2020-05-08 | 深圳市菲鹏生物制药股份有限公司 | 调节cho-k1表达系统所分泌抗体的酸性峰含量的方法 |
EP4051790A4 (en) * | 2019-10-31 | 2023-11-01 | William Marsh Rice University | GENETICALLY ENGINEERED CELLS FOR CONTROLLED PRODUCTION |
WO2021112927A1 (en) | 2019-12-06 | 2021-06-10 | Regeneron Pharmaceuticals, Inc. | Anti-vegf protein compositions and methods for producing the same |
KR20220134541A (ko) | 2020-01-31 | 2022-10-05 | 추가이 세이야쿠 가부시키가이샤 | 착색을 억제한 폴리펩타이드를 포함하는 조성물의 제조 방법 |
JP7404930B2 (ja) | 2020-02-26 | 2023-12-26 | 富士フイルムビジネスイノベーション株式会社 | 発光装置、光学装置及び計測装置 |
JP7404929B2 (ja) | 2020-02-26 | 2023-12-26 | 富士フイルムビジネスイノベーション株式会社 | 発光装置、光学装置及び計測装置 |
WO2021226444A2 (en) | 2020-05-08 | 2021-11-11 | Regeneron Pharmaceuticals, Inc. | Vegf traps and mini-traps and methods for treating ocular disorders and cancer |
GB202012991D0 (en) | 2020-08-20 | 2020-10-07 | Ucb Biopharma Sprl | Cell culture processes |
CN116635416A (zh) * | 2020-12-22 | 2023-08-22 | 诺华股份有限公司 | 用于在细胞培养期间降低分泌的重组表达蛋白质中半胱氨酸残基的氧化水平的方法 |
GB202105424D0 (en) | 2021-04-16 | 2021-06-02 | UCB Biopharma SRL | Cell culture processes |
KR20240050373A (ko) | 2021-09-02 | 2024-04-18 | 베링거 인겔하임 인터내셔날 게엠베하 | 미래의 색값 또는 대응하는 특성을 결정하는 방법 및 이를 위한 장치 |
KR102682066B1 (ko) * | 2021-10-12 | 2024-07-05 | 프레스티지바이오로직스 주식회사 | 항체 집단의 제조 방법 |
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JO3672B1 (ar) * | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
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-
2013
- 2013-03-15 US US13/841,864 patent/US20130281355A1/en not_active Abandoned
- 2013-04-24 EP EP18213796.8A patent/EP3533864A1/en active Pending
- 2013-04-24 JP JP2015509107A patent/JP6367792B2/ja active Active
- 2013-04-24 NZ NZ701791A patent/NZ701791A/en unknown
- 2013-04-24 EP EP13720203.2A patent/EP2841561B1/en not_active Revoked
- 2013-04-24 PL PL13720203T patent/PL2841561T3/pl unknown
- 2013-04-24 KR KR1020147032389A patent/KR102115052B1/ko active IP Right Grant
- 2013-04-24 SI SI201331376T patent/SI2841561T1/sl unknown
- 2013-04-24 RU RU2014147018A patent/RU2678142C2/ru active
- 2013-04-24 KR KR1020207014171A patent/KR102339106B1/ko active IP Right Grant
- 2013-04-24 SG SG10201810830UA patent/SG10201810830UA/en unknown
- 2013-04-24 SG SG11201406903SA patent/SG11201406903SA/en unknown
- 2013-04-24 ES ES13720203T patent/ES2716301T3/es active Active
- 2013-04-24 MY MYPI2014003007A patent/MY181513A/en unknown
- 2013-04-24 MX MX2014012838A patent/MX363493B/es unknown
- 2013-04-24 CA CA2871006A patent/CA2871006C/en active Active
- 2013-04-24 AR ARP130101367 patent/AR090822A1/es unknown
- 2013-04-24 RU RU2018146497A patent/RU2018146497A/ru unknown
- 2013-04-24 CN CN201380032959.7A patent/CN104428409A/zh active Pending
- 2013-04-24 AU AU2013251647A patent/AU2013251647B2/en active Active
- 2013-04-24 BR BR112014026308A patent/BR112014026308A8/pt not_active Application Discontinuation
- 2013-04-24 CN CN202010250367.4A patent/CN111440758A/zh active Pending
- 2013-04-24 WO PCT/US2013/037992 patent/WO2013163294A1/en active Application Filing
-
2014
- 2014-10-21 IL IL235235A patent/IL235235A0/en unknown
- 2014-10-23 MX MX2019003427A patent/MX2019003427A/es unknown
- 2014-11-05 ZA ZA2014/08092A patent/ZA201408092B/en unknown
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2015
- 2015-09-17 HK HK15109118.1A patent/HK1208496A1/xx unknown
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2017
- 2017-11-03 ZA ZA2017/07452A patent/ZA201707452B/en unknown
-
2018
- 2018-07-05 JP JP2018128429A patent/JP7323272B2/ja active Active
-
2019
- 2019-03-11 HR HRP20190484TT patent/HRP20190484T1/hr unknown
- 2019-04-02 AU AU2019202259A patent/AU2019202259B2/en active Active
-
2021
- 2021-03-16 JP JP2021042702A patent/JP2021104023A/ja not_active Withdrawn
-
2023
- 2023-07-28 JP JP2023123219A patent/JP2023156371A/ja active Pending
- 2023-10-30 US US18/497,162 patent/US20240093143A1/en not_active Abandoned
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