MX346787B - Sulfato de controitina similar al de tiburon y proceso para la preparacion del mismo. - Google Patents

Sulfato de controitina similar al de tiburon y proceso para la preparacion del mismo.

Info

Publication number
MX346787B
MX346787B MX2013013325A MX2013013325A MX346787B MX 346787 B MX346787 B MX 346787B MX 2013013325 A MX2013013325 A MX 2013013325A MX 2013013325 A MX2013013325 A MX 2013013325A MX 346787 B MX346787 B MX 346787B
Authority
MX
Mexico
Prior art keywords
shark
chondroitin sulphate
preparation
sulphate
chondroitin
Prior art date
Application number
MX2013013325A
Other languages
English (en)
Other versions
MX2013013325A (es
Inventor
Valoti Ermanno
Miraglia Niccolò
Bianchi Davide
Valetti Marco
Bazza Paola
Original Assignee
Gnosis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Spa filed Critical Gnosis Spa
Publication of MX2013013325A publication Critical patent/MX2013013325A/es
Publication of MX346787B publication Critical patent/MX346787B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invención se refiere a un sulfato de condroitina similar al de tiburón y a un proceso para la preparación del mismo. En particular, la presente invención se refiere a un sulfato de condroitina similar al de tiburón, que muestra una cantidad muy baja de 4-sulfato, una densidad de carga alta y una actividad biológica comparable a los sulfatos de condroitina naturales; la invención también se refiere a un proceso para la preparación del sulfato de condroitina similar al de tiburón, proporcionando productividades sustancialmente más altas y mejor reproducibilidad de la calidad del producto. El sulfato de condroitina similar al de tiburón de la invención muestra una alta masa molecular y densidad de carga; su efectividad biológica y anti-inflamatoria in vitro, comparable a aquellas de los productos naturales hacen a este polisacárido potencialmente útil como un fármaco en preparaciones farmacéuticas y productos nutracéuticos.
MX2013013325A 2011-05-20 2011-05-20 Sulfato de controitina similar al de tiburon y proceso para la preparacion del mismo. MX346787B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2011/058297 WO2012159655A1 (en) 2011-05-20 2011-05-20 Shark-like chondroitin sulphate and process for the preparation thereof

Publications (2)

Publication Number Publication Date
MX2013013325A MX2013013325A (es) 2014-02-27
MX346787B true MX346787B (es) 2017-03-31

Family

ID=44626453

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013013325A MX346787B (es) 2011-05-20 2011-05-20 Sulfato de controitina similar al de tiburon y proceso para la preparacion del mismo.

Country Status (23)

Country Link
EP (1) EP2710043B1 (es)
JP (1) JP5770367B2 (es)
KR (1) KR101788536B1 (es)
CN (1) CN103635491B (es)
AU (1) AU2011369262B2 (es)
BR (1) BR112013029765B1 (es)
CA (1) CA2835691C (es)
CY (1) CY1117567T1 (es)
DK (1) DK2710043T3 (es)
EA (1) EA023370B1 (es)
ES (1) ES2584038T3 (es)
HR (1) HRP20160673T1 (es)
HU (1) HUE030096T2 (es)
IL (1) IL229432A (es)
MX (1) MX346787B (es)
NZ (1) NZ617808A (es)
PL (1) PL2710043T3 (es)
PT (1) PT2710043T (es)
RS (1) RS54854B1 (es)
SG (1) SG194936A1 (es)
SI (1) SI2710043T1 (es)
UA (1) UA110717C2 (es)
WO (1) WO2012159655A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20120896A1 (it) * 2012-05-23 2013-11-24 Bongulielmi Reto Condroitina per uso in medicina
ITMI20130117A1 (it) 2013-01-25 2014-07-26 Gnosis Spa Composizioni comprendenti condroitin solfato, enzimi proteolitici e composti sulfidrilati capaci di migliorare la biodisponibilita' del condroitin solfato
CN104877042B (zh) * 2015-06-10 2017-08-29 浙江三门恒康制药有限公司 一种类肝素的制备方法
IT202000004564A1 (it) 2020-03-04 2021-09-04 Lesaffre & Cie Processo per la solfatazione diretta di polisaccaridi in solvente ecologicamente accettabile

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2538404B1 (es) * 1982-12-28 1985-08-23 Anic Spa
JP3497209B2 (ja) * 1993-08-24 2004-02-16 生化学工業株式会社 硫酸化糖の脱硫酸化方法
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
IT1289613B1 (it) * 1997-02-07 1998-10-15 Inalco Spa Polisaccaridi batterici o-solfatati
ITMI20012200A1 (it) * 2001-10-22 2003-04-22 Ibsa Inst Biochimique Sa Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti
WO2007058252A1 (ja) 2005-11-17 2007-05-24 Seikagaku Corporation コンドロイチンの製造方法
EP1964924B1 (en) 2005-12-15 2015-09-30 Seikagaku Corporation Long-chain chondroitin sugar chain and method for producing the same and method for promoting synthesis of chondroitin
JP5622346B2 (ja) * 2006-05-19 2014-11-12 愛知県 神経細胞の細胞死抑制剤等
WO2008133350A1 (en) 2007-04-24 2008-11-06 Seikagaku Corporation Chondroitin-producing bacterium and method of producing chondroitin
JP2010215508A (ja) * 2007-06-25 2010-09-30 Pg Research:Kk 骨形成タンパク質活性調節剤
US9109243B2 (en) 2008-06-04 2015-08-18 Amano Enzyme Usa, Ltd. Microbial-derived chondroitin sulfate
IT1394311B1 (it) * 2009-05-25 2012-06-06 Altergon Sa Produzione biotecnologica di condroitina

Also Published As

Publication number Publication date
PL2710043T3 (pl) 2016-11-30
BR112013029765A2 (pt) 2017-01-17
KR101788536B1 (ko) 2017-10-20
CA2835691A1 (en) 2012-11-29
IL229432A0 (en) 2014-01-30
AU2011369262B2 (en) 2017-02-02
HUE030096T2 (en) 2017-04-28
WO2012159655A1 (en) 2012-11-29
KR20140044826A (ko) 2014-04-15
JP5770367B2 (ja) 2015-08-26
HRP20160673T1 (hr) 2016-07-01
UA110717C2 (uk) 2016-02-10
JP2014513742A (ja) 2014-06-05
NZ617808A (en) 2015-06-26
EA201391734A1 (ru) 2014-03-31
SI2710043T1 (sl) 2016-08-31
CY1117567T1 (el) 2017-04-26
CN103635491A (zh) 2014-03-12
ES2584038T3 (es) 2016-09-23
PT2710043T (pt) 2016-07-14
MX2013013325A (es) 2014-02-27
BR112013029765B1 (pt) 2021-02-17
SG194936A1 (en) 2013-12-30
DK2710043T3 (en) 2016-08-22
CA2835691C (en) 2018-08-21
RS54854B1 (sr) 2016-10-31
EA023370B1 (ru) 2016-05-31
CN103635491B (zh) 2016-05-11
AU2011369262A1 (en) 2013-11-28
IL229432A (en) 2017-09-28
EP2710043B1 (en) 2016-05-11
EP2710043A1 (en) 2014-03-26

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