MX2015012798A - Composiciones de gangliosido. - Google Patents
Composiciones de gangliosido.Info
- Publication number
- MX2015012798A MX2015012798A MX2015012798A MX2015012798A MX2015012798A MX 2015012798 A MX2015012798 A MX 2015012798A MX 2015012798 A MX2015012798 A MX 2015012798A MX 2015012798 A MX2015012798 A MX 2015012798A MX 2015012798 A MX2015012798 A MX 2015012798A
- Authority
- MX
- Mexico
- Prior art keywords
- cells
- gangliosides
- methods
- bone marrow
- production
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
Abstract
La invención proporciona gangliósidos novedosos y mezclas de gangliósidos novedosas y productos de fármaco que los contienen. La invención también proporciona células inducidas para sobre expresar uno o más gangliósidos. La invención además proporciona métodos para producción de gangliósidos, por ejemplo, GM1, a partir de células en cultivo usando, por ejemplo, células de médula ósea y células de neuroblastoma. Métodos incluyen el tratamiento de células con medio de inducción neural y cloroquina o cloroquina sola en el caso de por ejemplo, células de médula ósea humanas, neuraminidasa o glucosamina para inducir la producción de gangliósidos, por ejemplo, GM1, en las células. También se proporcionan métodos de largo plazo, de cultivo de alta densidad de células sin pasaje para producir gangliósidos, por ejemplo, GM1. Se proporcionan también métodos para cuantificar gangliósidos, por ejemplo, GM1 en cultivo celular.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361799519P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/029569 WO2014144953A1 (en) | 2013-03-15 | 2014-03-14 | Ganglioside compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015012798A true MX2015012798A (es) | 2016-06-10 |
Family
ID=51537838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012798A MX2015012798A (es) | 2013-03-15 | 2014-03-14 | Composiciones de gangliosido. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20150025234A1 (es) |
| EP (1) | EP2968378A4 (es) |
| JP (1) | JP2016521967A (es) |
| CN (1) | CN105142645A (es) |
| AU (1) | AU2014233521A1 (es) |
| CA (1) | CA2905700A1 (es) |
| IL (1) | IL240687A0 (es) |
| MX (1) | MX2015012798A (es) |
| SG (1) | SG11201506311YA (es) |
| WO (1) | WO2014144953A1 (es) |
| ZA (1) | ZA201505738B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102575275A (zh) | 2009-09-01 | 2012-07-11 | Lz治疗公司 | 用于提取和纯化神经节苷脂的方法 |
| WO2013109929A1 (en) | 2012-01-20 | 2013-07-25 | Garnet Biotherapeutics, Inc. | Methods of ganglioside production |
| JP6557575B2 (ja) * | 2015-10-23 | 2019-08-07 | 株式会社Adeka | エッチング液組成物及びエッチング方法 |
| CN105738527B (zh) * | 2016-03-11 | 2018-06-29 | 北京市药品检验所 | 使用氨基酸分析仪测定氨基葡萄糖的方法 |
| CN109721632B (zh) * | 2017-10-27 | 2023-10-31 | 齐鲁制药有限公司 | 一种高纯度神经节苷脂gm1及其制备方法 |
| CN109725068B (zh) * | 2017-10-27 | 2022-07-15 | 齐鲁制药有限公司 | 高效测定神经节苷脂gm1及其杂质的药物分析方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8506323A1 (es) * | 1984-01-04 | 1985-07-01 | Bioiberica | Procedimiento para la obtencion de un complejo glicoesfingolipidico |
| IT1199116B (it) * | 1984-07-03 | 1988-12-30 | Fidia Farmaceutici | Derivati di gangliosidi |
| US5532141A (en) * | 1995-06-13 | 1996-07-02 | Holler; Larry D. | Process for obtaining ganglioside lipids |
| US7851451B2 (en) * | 2004-03-12 | 2010-12-14 | Mti Meta Tech Inc. | Formulations for mediating inflammatory bowel disorders |
| CN102575275A (zh) * | 2009-09-01 | 2012-07-11 | Lz治疗公司 | 用于提取和纯化神经节苷脂的方法 |
| WO2013109929A1 (en) * | 2012-01-20 | 2013-07-25 | Garnet Biotherapeutics, Inc. | Methods of ganglioside production |
-
2014
- 2014-03-14 AU AU2014233521A patent/AU2014233521A1/en not_active Abandoned
- 2014-03-14 CN CN201480014653.3A patent/CN105142645A/zh active Pending
- 2014-03-14 WO PCT/US2014/029569 patent/WO2014144953A1/en active Application Filing
- 2014-03-14 US US14/214,333 patent/US20150025234A1/en not_active Abandoned
- 2014-03-14 CA CA2905700A patent/CA2905700A1/en not_active Abandoned
- 2014-03-14 SG SG11201506311YA patent/SG11201506311YA/en unknown
- 2014-03-14 JP JP2016503144A patent/JP2016521967A/ja active Pending
- 2014-03-14 MX MX2015012798A patent/MX2015012798A/es unknown
- 2014-03-14 EP EP14764212.8A patent/EP2968378A4/en not_active Withdrawn
-
2015
- 2015-08-11 ZA ZA2015/05738A patent/ZA201505738B/en unknown
- 2015-08-20 IL IL240687A patent/IL240687A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014144953A1 (en) | 2014-09-18 |
| ZA201505738B (en) | 2017-11-29 |
| SG11201506311YA (en) | 2015-09-29 |
| EP2968378A1 (en) | 2016-01-20 |
| CA2905700A1 (en) | 2014-09-18 |
| AU2014233521A1 (en) | 2015-08-20 |
| US20150025234A1 (en) | 2015-01-22 |
| IL240687A0 (en) | 2015-10-29 |
| EP2968378A4 (en) | 2016-08-31 |
| CN105142645A (zh) | 2015-12-09 |
| JP2016521967A (ja) | 2016-07-28 |
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