TWI780493B - 包含調酸素衍生物之治療高血脂症的組成物 - Google Patents

包含調酸素衍生物之治療高血脂症的組成物 Download PDF

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TWI780493B
TWI780493B TW109133876A TW109133876A TWI780493B TW I780493 B TWI780493 B TW I780493B TW 109133876 A TW109133876 A TW 109133876A TW 109133876 A TW109133876 A TW 109133876A TW I780493 B TWI780493 B TW I780493B
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tomodulin
mod
artificial sequence
res
fatty liver
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TW109133876A
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TW202106338A (zh
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鄭聖燁
金鎮善
張明賢
李相賢
崔仁榮
權世昌
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南韓商韓美藥品股份有限公司
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    • AHUMAN NECESSITIES
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
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    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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TW109133876A 2012-07-25 2013-07-25 包含調酸素衍生物之治療高血脂症的組成物 TWI780493B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2012-0081475 2012-07-25
KR1020120081475A KR101968344B1 (ko) 2012-07-25 2012-07-25 옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물

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TW202106338A TW202106338A (zh) 2021-02-16
TWI780493B true TWI780493B (zh) 2022-10-11

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TW109133876A TWI780493B (zh) 2012-07-25 2013-07-25 包含調酸素衍生物之治療高血脂症的組成物
TW102126623A TWI661837B (zh) 2012-07-25 2013-07-25 包含調酸素衍生物之治療高血脂症的組成物
TW106127084A TWI708614B (zh) 2012-07-25 2013-07-25 包含調酸素衍生物之治療高血脂症的組成物

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TW106127084A TWI708614B (zh) 2012-07-25 2013-07-25 包含調酸素衍生物之治療高血脂症的組成物

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US (3) US20150182593A1 (enExample)
EP (3) EP3384925B1 (enExample)
JP (4) JP2015524427A (enExample)
KR (1) KR101968344B1 (enExample)
CN (2) CN107854691B (enExample)
AR (1) AR091903A1 (enExample)
AU (2) AU2013293714B2 (enExample)
BR (2) BR122022025353B1 (enExample)
CA (2) CA2888407C (enExample)
CL (4) CL2015000177A1 (enExample)
DK (1) DK3384925T3 (enExample)
ES (2) ES2842881T3 (enExample)
IL (2) IL236913B (enExample)
MX (2) MX360024B (enExample)
MY (2) MY171493A (enExample)
NZ (2) NZ705384A (enExample)
PE (1) PE20150633A1 (enExample)
PH (2) PH12015500158B1 (enExample)
RU (2) RU2768853C1 (enExample)
SG (2) SG10201700527UA (enExample)
TW (3) TWI780493B (enExample)
UA (2) UA128812C2 (enExample)
WO (1) WO2014017843A1 (enExample)
ZA (2) ZA201501238B (enExample)

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ES2692187T3 (es) 2011-06-10 2018-11-30 Hanmi Science Co., Ltd. Nuevos derivados de oxintomodulina y composición farmacéutica para el tratamiento de obesidad que lo comprende
PH12013502517A1 (en) 2011-06-17 2014-01-20 Hanmi Science Co Ltd A conjugate comprising oxyntomodulin and an immunoglobulin fragment, and use thereof
KR20130049671A (ko) 2011-11-04 2013-05-14 한미사이언스 주식회사 생리활성 폴리펩타이드 결합체 제조 방법
AR090281A1 (es) 2012-03-08 2014-10-29 Hanmi Science Co Ltd Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo
KR101968344B1 (ko) 2012-07-25 2019-04-12 한미약품 주식회사 옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
ES2748158T3 (es) 2012-11-06 2020-03-13 Hanmi Pharm Ind Co Ltd Formulación líquida de conjugado de proteínas que comprende la oxintomodulina y un fragmento de inmunoglobulina
KR101993393B1 (ko) 2012-11-06 2019-10-01 한미약품 주식회사 옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물
MX362190B (es) 2012-12-21 2019-01-08 Sanofi Sa Agonistas duales de glp1/gip o trigonales de glp1/gip/glucagon.
WO2015086729A1 (en) 2013-12-13 2015-06-18 Sanofi Dual glp-1/gip receptor agonists
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CA2888407C (en) 2021-08-03
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CL2017002432A1 (es) 2018-04-02

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