TWI750189B - 一種治療冠狀動脈粥樣硬化及其併發症的方法 - Google Patents

一種治療冠狀動脈粥樣硬化及其併發症的方法 Download PDF

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TWI750189B
TWI750189B TW106120465A TW106120465A TWI750189B TW I750189 B TWI750189 B TW I750189B TW 106120465 A TW106120465 A TW 106120465A TW 106120465 A TW106120465 A TW 106120465A TW I750189 B TWI750189 B TW I750189B
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plasminogen
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TW106120465A
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TW201822799A (zh
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李季男
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大陸商深圳瑞健生命科學研究院有限公司
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
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  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW106120465A 2016-12-15 2017-06-19 一種治療冠狀動脈粥樣硬化及其併發症的方法 TWI750189B (zh)

Applications Claiming Priority (6)

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CN2016110168 2016-12-15
WOPCT/CN2016/110168 2016-12-15
??PCT/CN2016/110168 2016-12-15
??PCT/CN2016/110172 2016-12-15
CN2016110172 2016-12-15
WOPCT/CN2016/110172 2016-12-15

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TW201822799A TW201822799A (zh) 2018-07-01
TWI750189B true TWI750189B (zh) 2021-12-21

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TW106120465A TWI750189B (zh) 2016-12-15 2017-06-19 一種治療冠狀動脈粥樣硬化及其併發症的方法
TW110105040A TW202123963A (zh) 2016-12-15 2017-06-19 一種治療冠狀動脈粥樣硬化及其併發症的方法
TW106120492A TWI746580B (zh) 2016-12-15 2017-06-19 纖溶酶原在製備預防和治療脂肪代謝紊亂及其相關病症的藥物中的用途
TW106120499A TW201822810A (zh) 2016-12-15 2017-06-19 一種預防和治療脂肪肝的方法
TW106120464A TWI684459B (zh) 2016-12-15 2017-06-19 一種治療動脈粥樣硬化及其併發症的方法
TW106120501A TW201822812A (zh) 2016-12-15 2017-06-19 一種預防和治療肥胖症的方法
TW106120463A TWI680764B (zh) 2016-12-15 2017-06-19 一種預防動脈粥樣硬化及其併發症的方法
TW106120491A TW201822805A (zh) 2016-12-15 2017-06-19 一種預防和治療脂肪異常沉積導致的組織損傷的方法
TW106120498A TW201822809A (zh) 2016-12-15 2017-06-19 一種預防和治療高脂血症的方法

Family Applications After (8)

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TW110105040A TW202123963A (zh) 2016-12-15 2017-06-19 一種治療冠狀動脈粥樣硬化及其併發症的方法
TW106120492A TWI746580B (zh) 2016-12-15 2017-06-19 纖溶酶原在製備預防和治療脂肪代謝紊亂及其相關病症的藥物中的用途
TW106120499A TW201822810A (zh) 2016-12-15 2017-06-19 一種預防和治療脂肪肝的方法
TW106120464A TWI684459B (zh) 2016-12-15 2017-06-19 一種治療動脈粥樣硬化及其併發症的方法
TW106120501A TW201822812A (zh) 2016-12-15 2017-06-19 一種預防和治療肥胖症的方法
TW106120463A TWI680764B (zh) 2016-12-15 2017-06-19 一種預防動脈粥樣硬化及其併發症的方法
TW106120491A TW201822805A (zh) 2016-12-15 2017-06-19 一種預防和治療脂肪異常沉積導致的組織損傷的方法
TW106120498A TW201822809A (zh) 2016-12-15 2017-06-19 一種預防和治療高脂血症的方法

Country Status (7)

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US (4) US11547746B2 (enExample)
EP (4) EP3556393A4 (enExample)
JP (4) JP7161217B2 (enExample)
CN (4) CN110366425A (enExample)
CA (4) CA3047167A1 (enExample)
TW (9) TWI750189B (enExample)
WO (8) WO2018107687A1 (enExample)

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WO2017101871A1 (zh) * 2015-12-18 2017-06-22 深圳瑞健生命科学研究院有限公司 一种预防和治疗心血管病的新方法
TWI750189B (zh) * 2016-12-15 2021-12-21 大陸商深圳瑞健生命科學研究院有限公司 一種治療冠狀動脈粥樣硬化及其併發症的方法
JP7168990B2 (ja) 2016-12-15 2022-11-10 タレンゲン インターナショナル リミテッド 肥満症を予防および治療するための方法および薬物
TWI677348B (zh) 2016-12-15 2019-11-21 大陸商深圳瑞健生命科學研究院有限公司 一種改善心臟病變的方法
JP7213552B2 (ja) 2016-12-15 2023-01-27 タレンゲン インターナショナル リミテッド 肝の繊維化を予防及び治療するための方法
WO2018107701A1 (zh) 2016-12-15 2018-06-21 深圳瑞健生命科学研究院有限公司 一种新的降血糖和提高糖耐量的药物
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JP7624238B2 (ja) * 2020-03-24 2025-01-30 タレンゲン インターナショナル リミテッド ハンチントン病を治療する方法及び薬剤
KR20230005298A (ko) * 2020-05-11 2023-01-09 탈렌젠 인터내셔널 리미티드 척수성 근위축증의 치료 방법 및 약물
CN112056563A (zh) * 2020-09-15 2020-12-11 王胜林 用于修复脂质代谢障碍的营养素组合物及其应用
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