TWI724049B - 碘美醇的創新製備法及結晶化法 - Google Patents
碘美醇的創新製備法及結晶化法 Download PDFInfo
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- TWI724049B TWI724049B TW105135469A TW105135469A TWI724049B TW I724049 B TWI724049 B TW I724049B TW 105135469 A TW105135469 A TW 105135469A TW 105135469 A TW105135469 A TW 105135469A TW I724049 B TWI724049 B TW I724049B
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Classifications
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- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
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- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D2009/0086—Processes or apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00051—Controlling the temperature
- B01J2219/00139—Controlling the temperature using electromagnetic heating
- B01J2219/00141—Microwaves
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
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| KR102128423B1 (ko) * | 2018-09-17 | 2020-07-01 | (주)유케이케미팜 | 조영제 이오메프롤의 제조방법 |
| CN111777525B (zh) * | 2019-04-04 | 2021-08-27 | 成都西岭源药业有限公司 | 一种碘克沙醇的精制方法 |
| KR102179649B1 (ko) * | 2019-10-11 | 2020-11-18 | (주)에이에스텍 | 디에틸아미노하이드록시벤조일헥실벤조에이트의 제조 방법 |
| CN115931935A (zh) * | 2022-12-28 | 2023-04-07 | 深圳晶泰科技有限公司 | 一种提高微晶电子衍射数据质量的方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6072069A (en) * | 1998-11-04 | 2000-06-06 | Biophysica, Inc. | Biodegradable nonionic contrast media |
| WO2007013815A1 (en) * | 2005-07-29 | 2007-02-01 | Ge Healthcare As | Continuous crystallisation process of iodinated phenyl derivatives |
| WO2009091758A1 (en) * | 2008-01-14 | 2009-07-23 | Mallinckrodt Inc. | Process for the preparation of iosimenol |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698739A (en) * | 1989-07-05 | 1997-12-16 | Schering Aktiengesellschaft | Carboxamide non-ionic contrast media |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6072069A (en) * | 1998-11-04 | 2000-06-06 | Biophysica, Inc. | Biodegradable nonionic contrast media |
| WO2007013815A1 (en) * | 2005-07-29 | 2007-02-01 | Ge Healthcare As | Continuous crystallisation process of iodinated phenyl derivatives |
| WO2009091758A1 (en) * | 2008-01-14 | 2009-07-23 | Mallinckrodt Inc. | Process for the preparation of iosimenol |
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| SG11201803241YA (en) | 2018-05-30 |
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| AU2016350219A1 (en) | 2018-05-17 |
| SI3371147T1 (sl) | 2021-08-31 |
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