SI3371147T1 - Inovativna priprava in kristalizacija iosimenola - Google Patents
Inovativna priprava in kristalizacija iosimenolaInfo
- Publication number
- SI3371147T1 SI3371147T1 SI201631172T SI201631172T SI3371147T1 SI 3371147 T1 SI3371147 T1 SI 3371147T1 SI 201631172 T SI201631172 T SI 201631172T SI 201631172 T SI201631172 T SI 201631172T SI 3371147 T1 SI3371147 T1 SI 3371147T1
- Authority
- SI
- Slovenia
- Prior art keywords
- iosimenol
- crystallization
- innovative preparation
- innovative
- preparation
- Prior art date
Links
- DLPPIGPJCKKVBA-UHFFFAOYSA-N Iosimenol Chemical compound OCC(O)CNC(=O)C1=C(I)C(C(=O)N)=C(I)C(N(CC(O)CO)C(=O)CC(=O)N(CC(O)CO)C=2C(=C(C(=O)NCC(O)CO)C(I)=C(C(N)=O)C=2I)I)=C1I DLPPIGPJCKKVBA-UHFFFAOYSA-N 0.000 title 1
- 238000002425 crystallisation Methods 0.000 title 1
- 230000008025 crystallization Effects 0.000 title 1
- 229950004246 iosimenol Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0081—Use of vibrations, e.g. ultrasound
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J19/10—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing sonic or ultrasonic vibrations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D2009/0086—Processes or apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00051—Controlling the temperature
- B01J2219/00139—Controlling the temperature using electromagnetic heating
- B01J2219/00141—Microwaves
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562250720P | 2015-11-04 | 2015-11-04 | |
| EP16798573.8A EP3371147B1 (en) | 2015-11-04 | 2016-11-02 | Innovative preparation and crystallization of iosimenol |
| PCT/JP2016/004798 WO2017077710A1 (en) | 2015-11-04 | 2016-11-02 | Innovative preparation and crystallization of iosimenol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3371147T1 true SI3371147T1 (sl) | 2021-08-31 |
Family
ID=57354423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201631172T SI3371147T1 (sl) | 2015-11-04 | 2016-11-02 | Inovativna priprava in kristalizacija iosimenola |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10544089B2 (enExample) |
| EP (1) | EP3371147B1 (enExample) |
| JP (1) | JP6778746B2 (enExample) |
| KR (1) | KR20180077198A (enExample) |
| CN (1) | CN108368031B (enExample) |
| AU (2) | AU2016350219B2 (enExample) |
| CA (1) | CA3002502A1 (enExample) |
| CY (1) | CY1124164T1 (enExample) |
| DK (1) | DK3371147T3 (enExample) |
| ES (1) | ES2873828T3 (enExample) |
| HR (1) | HRP20210820T1 (enExample) |
| HU (1) | HUE054876T2 (enExample) |
| LT (1) | LT3371147T (enExample) |
| MY (1) | MY186399A (enExample) |
| NZ (1) | NZ742104A (enExample) |
| PH (1) | PH12018500872A1 (enExample) |
| PL (1) | PL3371147T3 (enExample) |
| PT (1) | PT3371147T (enExample) |
| SA (1) | SA518391413B1 (enExample) |
| SG (1) | SG11201803241YA (enExample) |
| SI (1) | SI3371147T1 (enExample) |
| TW (1) | TWI724049B (enExample) |
| WO (1) | WO2017077710A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102128423B1 (ko) * | 2018-09-17 | 2020-07-01 | (주)유케이케미팜 | 조영제 이오메프롤의 제조방법 |
| CN111777525B (zh) * | 2019-04-04 | 2021-08-27 | 成都西岭源药业有限公司 | 一种碘克沙醇的精制方法 |
| KR102179649B1 (ko) * | 2019-10-11 | 2020-11-18 | (주)에이에스텍 | 디에틸아미노하이드록시벤조일헥실벤조에이트의 제조 방법 |
| CN115931935A (zh) * | 2022-12-28 | 2023-04-07 | 深圳晶泰科技有限公司 | 一种提高微晶电子衍射数据质量的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698739A (en) * | 1989-07-05 | 1997-12-16 | Schering Aktiengesellschaft | Carboxamide non-ionic contrast media |
| US6072069A (en) * | 1998-11-04 | 2000-06-06 | Biophysica, Inc. | Biodegradable nonionic contrast media |
| NO20053687D0 (no) * | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process. |
| JP2011509943A (ja) * | 2008-01-14 | 2011-03-31 | マリンクロッド・インコーポレイテッド | イオシメノールを調製するためのプロセス |
-
2016
- 2016-11-02 NZ NZ742104A patent/NZ742104A/en not_active IP Right Cessation
- 2016-11-02 WO PCT/JP2016/004798 patent/WO2017077710A1/en not_active Ceased
- 2016-11-02 KR KR1020187014635A patent/KR20180077198A/ko not_active Withdrawn
- 2016-11-02 CN CN201680066838.8A patent/CN108368031B/zh not_active Expired - Fee Related
- 2016-11-02 US US15/772,710 patent/US10544089B2/en not_active Expired - Fee Related
- 2016-11-02 PT PT167985738T patent/PT3371147T/pt unknown
- 2016-11-02 MY MYPI2018701574A patent/MY186399A/en unknown
- 2016-11-02 HR HRP20210820TT patent/HRP20210820T1/hr unknown
- 2016-11-02 JP JP2018522702A patent/JP6778746B2/ja not_active Expired - Fee Related
- 2016-11-02 AU AU2016350219A patent/AU2016350219B2/en not_active Ceased
- 2016-11-02 SI SI201631172T patent/SI3371147T1/sl unknown
- 2016-11-02 TW TW105135469A patent/TWI724049B/zh not_active IP Right Cessation
- 2016-11-02 CA CA3002502A patent/CA3002502A1/en not_active Abandoned
- 2016-11-02 EP EP16798573.8A patent/EP3371147B1/en active Active
- 2016-11-02 LT LTEP16798573.8T patent/LT3371147T/lt unknown
- 2016-11-02 HU HUE16798573A patent/HUE054876T2/hu unknown
- 2016-11-02 DK DK16798573.8T patent/DK3371147T3/da active
- 2016-11-02 PL PL16798573T patent/PL3371147T3/pl unknown
- 2016-11-02 ES ES16798573T patent/ES2873828T3/es active Active
- 2016-11-02 SG SG11201803241YA patent/SG11201803241YA/en unknown
-
2018
- 2018-04-22 SA SA518391413A patent/SA518391413B1/ar unknown
- 2018-04-23 PH PH12018500872A patent/PH12018500872A1/en unknown
-
2021
- 2021-05-18 CY CY20211100428T patent/CY1124164T1/el unknown
- 2021-07-16 AU AU2021205101A patent/AU2021205101B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20180077198A (ko) | 2018-07-06 |
| NZ742104A (en) | 2023-01-27 |
| HK1257821A1 (en) | 2019-11-01 |
| EP3371147B1 (en) | 2021-04-07 |
| AU2021205101A1 (en) | 2021-08-19 |
| PL3371147T3 (pl) | 2021-10-25 |
| SG11201803241YA (en) | 2018-05-30 |
| TW201722906A (zh) | 2017-07-01 |
| DK3371147T3 (da) | 2021-05-25 |
| ES2873828T3 (es) | 2021-11-04 |
| JP6778746B2 (ja) | 2020-11-04 |
| US10544089B2 (en) | 2020-01-28 |
| HRP20210820T1 (hr) | 2021-06-25 |
| CN108368031B (zh) | 2022-05-03 |
| MY186399A (en) | 2021-07-22 |
| PT3371147T (pt) | 2021-05-24 |
| AU2016350219B2 (en) | 2021-04-29 |
| WO2017077710A1 (en) | 2017-05-11 |
| SA518391413B1 (ar) | 2022-03-06 |
| AU2021205101B2 (en) | 2022-11-24 |
| CN108368031A (zh) | 2018-08-03 |
| EP3371147A1 (en) | 2018-09-12 |
| PH12018500872A1 (en) | 2018-11-05 |
| LT3371147T (lt) | 2021-08-10 |
| TWI724049B (zh) | 2021-04-11 |
| US20190177266A1 (en) | 2019-06-13 |
| HUE054876T2 (hu) | 2021-10-28 |
| CY1124164T1 (el) | 2022-05-27 |
| AU2016350219A1 (en) | 2018-05-17 |
| CA3002502A1 (en) | 2017-05-11 |
| JP2018536654A (ja) | 2018-12-13 |
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