TWI606064B - 細胞死亡誘導分子（ｃｄｉｍ）結合蛋白類及彼等之用途 - Google Patents
細胞死亡誘導分子（ｃｄｉｍ）結合蛋白類及彼等之用途 Download PDFInfo
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Landscapes
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| DK3265575T3 (da) * | 2015-03-04 | 2021-05-31 | Igm Biosciences Inc | Cd20-bindende molekyler og anvendelser deraf |
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| WO2016168758A1 (en) | 2015-04-17 | 2016-10-20 | Igm Biosciences, Inc. | Multi-valent human immunodeficiency virus antigen binding molecules and uses thereof |
| EP3824903A1 (en) | 2015-09-30 | 2021-05-26 | IGM Biosciences Inc. | Binding molecules with modified j-chain |
| DK3356401T3 (da) | 2015-09-30 | 2020-09-07 | Igm Biosciences Inc | Bindingsmolekyler med modificeret j-kæde |
| EP3455257B1 (en) | 2016-05-09 | 2021-09-22 | IGM Biosciences Inc. | Anti-pd-l1 antibodies |
| JP6851391B2 (ja) * | 2016-08-15 | 2021-03-31 | ノバルティス アーゲー | オファツムマブを用いた多発性硬化症の治療レジメンおよび治療方法 |
| KR20190118172A (ko) | 2017-02-08 | 2019-10-17 | 드래곤플라이 쎄라퓨틱스, 인크. | 천연 킬러 세포의 활성화를 위한 다중-특이적 결합 단백질 및 암 치료에서의 그의 치료적 용도 |
| EP3579866A4 (en) * | 2017-02-08 | 2020-12-09 | Dragonfly Therapeutics, Inc. | HEAVY CHAIN VARIABLE ANTIBODY DOMAINS WITH NKG2D RECEPTOR AIMING |
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| MX2020008333A (es) | 2018-02-08 | 2020-09-21 | Dragonfly Therapeutics Inc | Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales. |
| WO2019157366A1 (en) | 2018-02-08 | 2019-08-15 | Dragonfly Therapeutics, Inc. | Antibody variable domains targeting the nkg2d receptor |
| MX2020008684A (es) | 2018-02-20 | 2020-12-07 | Dragonfly Therapeutics Inc | Proteinas de union multiespecificas que se unen a cd33, nkg2d y cd16 y metodos de uso. |
| MX2020009069A (es) | 2018-03-01 | 2020-10-08 | Igm Biosciences Inc | Mutaciones de fc de igm y de la cadena j que afectan la semivida de igm en suero. |
| CA3108427A1 (en) | 2018-08-08 | 2020-02-13 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| MX2021001527A (es) | 2018-08-08 | 2021-06-15 | Dragonfly Therapeutics Inc | Proteínas de unión a nkg2d, cd16 y a un antígeno asociado a tumor. |
| WO2020102555A1 (en) * | 2018-11-16 | 2020-05-22 | Memorial Sloan Kettering Cancer Center | Antibodies to mucin-16 and methods of use thereof |
| JP2022544405A (ja) | 2019-08-15 | 2022-10-18 | アイジーエム バイオサイエンシズ インコーポレイテッド | 免疫刺激性多量体型結合分子 |
| EP4146271A4 (en) | 2020-05-06 | 2024-09-04 | Dragonfly Therapeutics, Inc. | PROTEINS THAT BIND NKG2D, CD16 AND CLEC12A |
| WO2022133169A1 (en) | 2020-12-18 | 2022-06-23 | Century Therapeutics, Inc. | Chimeric antigen receptor systems with adaptable receptor specificity |
| EP4301774A4 (en) | 2021-03-03 | 2025-08-13 | Dragonfly Therapeutics Inc | METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN |
| CN114181318B (zh) * | 2021-11-08 | 2023-08-01 | 四川大学 | 一种组织特异性表达穿透血脑屏障的idua融合蛋白的重组腺相关病毒及应用 |
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| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
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2013
- 2013-02-08 TW TW102105337A patent/TWI606064B/zh active
- 2013-02-08 IN IN1781MUN2014 patent/IN2014MN01781A/en unknown
- 2013-02-08 CA CA2863714A patent/CA2863714C/en active Active
- 2013-02-08 MX MX2014009628A patent/MX363819B/es active IP Right Grant
- 2013-02-08 JP JP2014556751A patent/JP6335796B2/ja active Active
- 2013-02-08 DK DK13713588.5T patent/DK2812356T3/da active
- 2013-02-08 AU AU2013200903A patent/AU2013200903B2/en active Active
- 2013-02-08 ES ES13713588T patent/ES2735289T3/es active Active
- 2013-02-08 US US13/763,398 patent/US9409976B2/en active Active
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- 2013-02-08 BR BR112014019459-9A patent/BR112014019459B1/pt active IP Right Grant
- 2013-02-08 EP EP13713588.5A patent/EP2812356B1/en active Active
- 2013-02-08 WO PCT/US2013/025430 patent/WO2013120012A2/en not_active Ceased
- 2013-02-08 KR KR1020147025110A patent/KR102102111B1/ko active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100322849A1 (en) * | 2003-11-05 | 2010-12-23 | Bhat Neelima M | Enhanced b cell cytotoxicity of cdim binding antibody |
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| Bhat NM et al., Scand J Immunol. 2000 Feb;51(2):134-40. Bhat NM et al., Crit Rev Oncol Hematol. 2001 Jul-Aug;39(1-2):59-68. * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR102102111B1 (ko) | 2020-04-20 |
| AU2013200903A1 (en) | 2013-08-22 |
| EP2812356A2 (en) | 2014-12-17 |
| DK2812356T3 (da) | 2019-07-08 |
| MX2014009628A (es) | 2015-03-19 |
| EP2812356B1 (en) | 2019-03-27 |
| AU2013200903B2 (en) | 2015-05-14 |
| BR112014019459A8 (pt) | 2023-01-10 |
| US20140044739A1 (en) | 2014-02-13 |
| IN2014MN01781A (enExample) | 2015-07-03 |
| WO2013120012A3 (en) | 2013-11-07 |
| BR112014019459B1 (pt) | 2023-04-18 |
| JP2015511817A (ja) | 2015-04-23 |
| TW201345921A (zh) | 2013-11-16 |
| BR112014019459A2 (pt) | 2017-06-27 |
| ES2735289T3 (es) | 2019-12-17 |
| KR20150001728A (ko) | 2015-01-06 |
| WO2013120012A2 (en) | 2013-08-15 |
| CA2863714A1 (en) | 2013-08-15 |
| CN104254544B (zh) | 2017-04-26 |
| HK1205136A1 (en) | 2015-12-11 |
| CN104254544A (zh) | 2014-12-31 |
| JP6335796B2 (ja) | 2018-06-06 |
| CA2863714C (en) | 2022-07-05 |
| MX363819B (es) | 2019-04-03 |
| US9409976B2 (en) | 2016-08-09 |
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