TWI543780B - 雙叉乳酸桿菌大腸遞送膠囊及其製造方法 - Google Patents

雙叉乳酸桿菌大腸遞送膠囊及其製造方法 Download PDF

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Publication number
TWI543780B
TWI543780B TW100143797A TW100143797A TWI543780B TW I543780 B TWI543780 B TW I543780B TW 100143797 A TW100143797 A TW 100143797A TW 100143797 A TW100143797 A TW 100143797A TW I543780 B TWI543780 B TW I543780B
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TW
Taiwan
Prior art keywords
capsule
chitosan
mass
large intestine
coating
Prior art date
Application number
TW100143797A
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English (en)
Chinese (zh)
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TW201249481A (en
Inventor
峯村剛
今村奈津子
山中邦昭
Original Assignee
日清藥業股份有限公司
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Application filed by 日清藥業股份有限公司 filed Critical 日清藥業股份有限公司
Publication of TW201249481A publication Critical patent/TW201249481A/zh
Application granted granted Critical
Publication of TWI543780B publication Critical patent/TWI543780B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TW100143797A 2010-12-28 2011-11-29 雙叉乳酸桿菌大腸遞送膠囊及其製造方法 TWI543780B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010293842 2010-12-28
JP2011250418A JP5087167B2 (ja) 2010-12-28 2011-11-16 ビフィズス菌大腸デリバリーカプセル及びその製造方法

Publications (2)

Publication Number Publication Date
TW201249481A TW201249481A (en) 2012-12-16
TWI543780B true TWI543780B (zh) 2016-08-01

Family

ID=46382743

Family Applications (1)

Application Number Title Priority Date Filing Date
TW100143797A TWI543780B (zh) 2010-12-28 2011-11-29 雙叉乳酸桿菌大腸遞送膠囊及其製造方法

Country Status (5)

Country Link
JP (1) JP5087167B2 (ja)
KR (1) KR20130133809A (ja)
CN (1) CN103327990A (ja)
TW (1) TWI543780B (ja)
WO (1) WO2012090623A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5102401B1 (ja) * 2012-03-30 2012-12-19 森下仁丹株式会社 大腸特異崩壊性カプセル
CN104968356A (zh) * 2012-12-21 2015-10-07 日清药业股份有限公司 大肠输送胶囊及其制备方法
JP5496432B1 (ja) * 2012-12-21 2014-05-21 日清ファルマ株式会社 大腸送達カプセル及びその製造方法
JP6243276B2 (ja) * 2014-03-31 2017-12-06 株式会社ファンケル 原薬の耐酸性を向上させたハードカプセル製剤
JP6457963B2 (ja) * 2016-02-25 2019-01-23 日清ファルマ株式会社 大腸デリバリーカプセル製剤
CN108066296B (zh) * 2016-11-11 2020-11-17 南京益恒寿生命科技有限公司 一种生物学活性组分结肠靶向组合物及其应用
CN109464425B (zh) * 2018-12-29 2021-02-05 上海交大昂立股份有限公司 一种益生菌包埋颗粒及其制备方法
JP6578459B1 (ja) * 2019-02-28 2019-09-18 アピ株式会社 ハードカプセル及びその製造方法
JP2021014422A (ja) * 2019-07-11 2021-02-12 日清ファルマ株式会社 便性改善剤
JP2021014421A (ja) * 2019-07-11 2021-02-12 日清ファルマ株式会社 Ｑｏｌ改善剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0669476B2 (ja) * 1986-11-07 1994-09-07 新次郎 辻 ゼラチン硬カプセルのフイルムコ−テイング方法
US7604820B1 (en) * 1999-08-09 2009-10-20 Dainippon Sumitomo Pharma Co., Ltd. Solid preparation containing chitosan powder and process for producing the same
JP2003012526A (ja) * 2001-06-27 2003-01-15 Sunstar Inc 有用生菌内包製剤
EP2105144A4 (en) * 2006-12-21 2012-08-29 Aicello Chemical Co CHITOSAN SOLUTION AND MEDICAL PREPARATION WITH CHITOSAN COATING FROM THE SOLUTION
JP5487379B2 (ja) * 2008-03-19 2014-05-07 森下仁丹株式会社 血中リン濃度上昇抑制剤

Also Published As

Publication number Publication date
TW201249481A (en) 2012-12-16
JP5087167B2 (ja) 2012-11-28
WO2012090623A1 (ja) 2012-07-05
JP2012149032A (ja) 2012-08-09
KR20130133809A (ko) 2013-12-09
CN103327990A (zh) 2013-09-25

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