TWI423802B - 用於治療阿茲海默症之藥劑 - Google Patents
用於治療阿茲海默症之藥劑 Download PDFInfo
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- TWI423802B TWI423802B TW097118634A TW97118634A TWI423802B TW I423802 B TWI423802 B TW I423802B TW 097118634 A TW097118634 A TW 097118634A TW 97118634 A TW97118634 A TW 97118634A TW I423802 B TWI423802 B TW I423802B
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- Prior art keywords
- salt
- disease
- hydrochloride
- winternipazole
- treating alzheimer
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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| JP2007135367 | 2007-05-22 |
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| TW200904428A TW200904428A (en) | 2009-02-01 |
| TWI423802B true TWI423802B (zh) | 2014-01-21 |
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| TW097118634A TWI423802B (zh) | 2007-05-22 | 2008-05-21 | 用於治療阿茲海默症之藥劑 |
| TW102147146A TWI489983B (zh) | 2007-05-22 | 2008-05-21 | 用於治療阿茲海默症之藥劑 |
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| TW102147146A TWI489983B (zh) | 2007-05-22 | 2008-05-21 | 用於治療阿茲海默症之藥劑 |
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| MY (1) | MY146407A (enExample) |
| NZ (1) | NZ581099A (enExample) |
| PL (1) | PL2157973T3 (enExample) |
| PT (1) | PT2157973E (enExample) |
| RU (1) | RU2469723C2 (enExample) |
| SI (1) | SI2157973T1 (enExample) |
| TW (2) | TWI423802B (enExample) |
| UA (1) | UA96633C2 (enExample) |
| WO (1) | WO2008143361A1 (enExample) |
| ZA (1) | ZA200908202B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2135607A1 (en) | 2008-06-18 | 2009-12-23 | Pharnext | Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders |
| US9387206B2 (en) | 2009-11-03 | 2016-07-12 | Pharnext | Therapeutic approaches for treating Alzheimer's disease |
| EP2322163A1 (en) * | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| SI2560631T1 (sl) | 2011-03-01 | 2014-06-30 | Pharnext | Na baklofenu in akamprosatu temeljeäśa terapija nevroloĺ kih nepravilnosti |
| US9241933B2 (en) | 2011-03-01 | 2016-01-26 | Pharnext | Compositions for treating amyotrophic lateral sclerosis |
| US10010515B2 (en) | 2011-03-01 | 2018-07-03 | Pharnext | Therapeutic approaches for treating Parkinson's disease |
| US9248111B2 (en) | 2011-03-01 | 2016-02-02 | Pharnext | Therapeutic approaches for treating parkinson's disease |
| MX2014015310A (es) | 2012-06-15 | 2015-07-06 | Found Biomedical Res & Innov | Agente profilactico y/o terapeutico para el deterioro cognoscitivo leve. |
| WO2015100255A2 (en) * | 2013-12-23 | 2015-07-02 | Holaday John W | Disposable container for air hydration |
| CN109310688B (zh) | 2016-05-19 | 2023-09-01 | 国立研究开发法人国立循环器病研究中心 | 用于预防和/或治疗痴呆症的药物 |
| HUE053636T2 (hu) | 2017-05-24 | 2021-07-28 | H Lundbeck As | 5-HT6 receptor antagonista és acetilkolin-észteráz inhibitor kombinációja Alzheimer-kór kezelésében történõ alkalmazásra ApoE4 alléleket hordozó betegek szubpopulációjában |
| CN107602523B (zh) * | 2017-09-11 | 2020-08-18 | 安徽中医药大学 | 京尼平类似物、制备方法及其应用 |
| PL237739B1 (pl) | 2018-06-06 | 2021-05-17 | Univ Gdanski | Genisteina do zastosowania do leczenia choroby Alzheimera |
| NL2024431B1 (en) | 2019-12-11 | 2021-09-07 | Sulfateq Bv | Compounds for treatment of alzheimer’s disease |
| CN117797095A (zh) * | 2023-11-30 | 2024-04-02 | 浙江大学 | 一种长效脂质液晶植入物及其治疗阿尔茨海默症的用途 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040229913A1 (en) * | 2002-12-13 | 2004-11-18 | Eisal Co., Ltd. | Therapeutic agent for severe Alzheimer's dementia |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535019A (en) * | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| JPS5649378A (en) | 1979-08-25 | 1981-05-02 | Otsuka Pharmaceut Co Ltd | Tetrazolylalkoxycarbostyril derivative |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| JP2574099B2 (ja) | 1992-05-21 | 1997-01-22 | 大塚製薬株式会社 | アレルギー疾患治療剤 |
| JPH10175864A (ja) | 1996-12-16 | 1998-06-30 | Otsuka Pharmaceut Co Ltd | 慢性閉塞性肺疾患治療剤 |
| US6428488B1 (en) * | 1997-08-28 | 2002-08-06 | Kenneth Kensey | Dual riser/dual capillary viscometer for newtonian and non-newtonian fluids |
| US6322525B1 (en) * | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Method of analyzing data from a circulating blood viscometer for determining absolute and effective blood viscosity |
| US6019735A (en) * | 1997-08-28 | 2000-02-01 | Visco Technologies, Inc. | Viscosity measuring apparatus and method of use |
| US6322524B1 (en) * | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Dual riser/single capillary viscometer |
| WO1999036405A1 (en) * | 1998-01-16 | 1999-07-22 | Eisai Co., Ltd. | Process for production of donepezil derivative |
| US6187790B1 (en) * | 1999-03-04 | 2001-02-13 | Neal R. Cutler | Use of cilostazol for treatment of sexual dysfunction |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6484565B2 (en) * | 1999-11-12 | 2002-11-26 | Drexel University | Single riser/single capillary viscometer using mass detection or column height detection |
| US6458804B1 (en) * | 2001-01-26 | 2002-10-01 | R.T. Alamo Venturesi, Llc | Methods for the treatment of central nervous system disorders in certain patient groups |
| TW200301135A (en) * | 2001-12-27 | 2003-07-01 | Otsuka Maryland Res Inst Inc | Pharmaceutical compositions comprising a multifunctional phosphodiesterase inhibitor and an adenosine uptake inhibitor |
| IL150509A (en) * | 2002-07-01 | 2007-07-04 | Joseph Kaspi | Pharmaceutical preparations containing donafazil hydrochloride |
| US6743806B2 (en) * | 2002-10-23 | 2004-06-01 | Otsuka Pharmaceutical Company, Limited | Active oxygen scavenger |
| FR2848452B1 (fr) * | 2002-12-12 | 2007-04-06 | Aventis Pharma Sa | Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer |
| TWI323660B (en) * | 2003-02-25 | 2010-04-21 | Otsuka Pharma Co Ltd | Pten inhibitor or maxi-k channels opener |
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2008
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- 2008-05-21 TW TW102147146A patent/TWI489983B/zh not_active IP Right Cessation
- 2008-05-21 CA CA2687289A patent/CA2687289C/en not_active Expired - Fee Related
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- 2008-05-21 JP JP2010509026A patent/JP5153870B2/ja not_active Expired - Fee Related
- 2008-05-21 DK DK08764779.8T patent/DK2157973T3/en active
- 2008-05-21 KR KR1020097026651A patent/KR101441725B1/ko not_active Expired - Fee Related
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- 2008-05-21 NZ NZ581099A patent/NZ581099A/en not_active IP Right Cessation
- 2008-05-21 PT PT87647798T patent/PT2157973E/pt unknown
- 2008-05-21 UA UAA200913247A patent/UA96633C2/uk unknown
- 2008-05-21 MX MX2009012583A patent/MX2009012583A/es active IP Right Grant
- 2008-05-21 AU AU2008253977A patent/AU2008253977B2/en not_active Ceased
- 2008-05-21 BR BRPI0811919-8A2A patent/BRPI0811919A2/pt not_active IP Right Cessation
- 2008-05-21 US US12/599,962 patent/US20100298375A1/en not_active Abandoned
- 2008-05-21 SI SI200831493T patent/SI2157973T1/sl unknown
- 2008-05-21 EP EP08764779.8A patent/EP2157973B1/en not_active Not-in-force
- 2008-05-21 PL PL08764779T patent/PL2157973T3/pl unknown
- 2008-05-21 MY MYPI20094815A patent/MY146407A/en unknown
- 2008-05-21 RU RU2009147456/15A patent/RU2469723C2/ru not_active IP Right Cessation
- 2008-05-21 WO PCT/JP2008/059763 patent/WO2008143361A1/en not_active Ceased
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- 2009-11-11 IL IL202053A patent/IL202053A/en not_active IP Right Cessation
- 2009-11-20 ZA ZA200908202A patent/ZA200908202B/xx unknown
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040229913A1 (en) * | 2002-12-13 | 2004-11-18 | Eisal Co., Ltd. | Therapeutic agent for severe Alzheimer's dementia |
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