ZA200908202B - A medicament comprising a carbostyril derivates and donepezil for treating alzheimer's disease - Google Patents

A medicament comprising a carbostyril derivates and donepezil for treating alzheimer's disease

Info

Publication number
ZA200908202B
ZA200908202B ZA200908202A ZA200908202A ZA200908202B ZA 200908202 B ZA200908202 B ZA 200908202B ZA 200908202 A ZA200908202 A ZA 200908202A ZA 200908202 A ZA200908202 A ZA 200908202A ZA 200908202 B ZA200908202 B ZA 200908202B
Authority
ZA
South Africa
Prior art keywords
carbostyril
donepezil
derivates
medicament
disease
Prior art date
Application number
ZA200908202A
Other languages
English (en)
Inventor
Heii Arai
Original Assignee
Otsuka Pharma Co Ltd
Univ Juntendo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd, Univ Juntendo filed Critical Otsuka Pharma Co Ltd
Publication of ZA200908202B publication Critical patent/ZA200908202B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200908202A 2007-05-22 2009-11-20 A medicament comprising a carbostyril derivates and donepezil for treating alzheimer's disease ZA200908202B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007135367 2007-05-22

Publications (1)

Publication Number Publication Date
ZA200908202B true ZA200908202B (en) 2010-07-28

Family

ID=39636992

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200908202A ZA200908202B (en) 2007-05-22 2009-11-20 A medicament comprising a carbostyril derivates and donepezil for treating alzheimer's disease

Country Status (27)

Country Link
US (1) US20100298375A1 (enExample)
EP (2) EP2157973B1 (enExample)
JP (1) JP5153870B2 (enExample)
KR (1) KR101441725B1 (enExample)
CN (1) CN101754758B (enExample)
AR (1) AR066664A1 (enExample)
AU (1) AU2008253977B2 (enExample)
BR (1) BRPI0811919A2 (enExample)
CA (1) CA2687289C (enExample)
CO (1) CO6251249A2 (enExample)
CY (1) CY1116683T1 (enExample)
DK (1) DK2157973T3 (enExample)
ES (1) ES2545959T3 (enExample)
HR (1) HRP20150843T1 (enExample)
HU (1) HUE025902T2 (enExample)
IL (1) IL202053A (enExample)
MX (1) MX2009012583A (enExample)
MY (1) MY146407A (enExample)
NZ (1) NZ581099A (enExample)
PL (1) PL2157973T3 (enExample)
PT (1) PT2157973E (enExample)
RU (1) RU2469723C2 (enExample)
SI (1) SI2157973T1 (enExample)
TW (2) TWI423802B (enExample)
UA (1) UA96633C2 (enExample)
WO (1) WO2008143361A1 (enExample)
ZA (1) ZA200908202B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2135607A1 (en) 2008-06-18 2009-12-23 Pharnext Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders
EP2322163A1 (en) * 2009-11-03 2011-05-18 Pharnext New therapeutics approaches for treating alzheimer disease
US9387206B2 (en) 2009-11-03 2016-07-12 Pharnext Therapeutic approaches for treating Alzheimer's disease
US9241933B2 (en) 2011-03-01 2016-01-26 Pharnext Compositions for treating amyotrophic lateral sclerosis
US9248111B2 (en) 2011-03-01 2016-02-02 Pharnext Therapeutic approaches for treating parkinson's disease
US10010515B2 (en) 2011-03-01 2018-07-03 Pharnext Therapeutic approaches for treating Parkinson's disease
ES2665569T3 (es) 2011-03-01 2018-04-26 Pharnext Tratamiento de la isquemia cerebral
RU2015101100A (ru) * 2012-06-15 2016-08-10 Фаундейшн Фор Байомедикал Рисерч Энд Инновейшн Профилактическое и/или терапевтическое средство для умеренного когнитивного нарушения
US20160331922A1 (en) * 2013-12-23 2016-11-17 John W. Holaday Disposable container for air hydration
EP3459545A4 (en) 2016-05-19 2020-02-26 National Cerebral and Cardiovascular Center MEDICATION FOR PREVENTING AND / OR TREATING DEMENTIA
CN111032038A (zh) 2017-05-24 2020-04-17 H.隆德贝克有限公司 用于治疗阿尔茨海默氏病的药物组合
CN107602523B (zh) * 2017-09-11 2020-08-18 安徽中医药大学 京尼平类似物、制备方法及其应用
PL237739B1 (pl) 2018-06-06 2021-05-17 Univ Gdanski Genisteina do zastosowania do leczenia choroby Alzheimera
NL2024431B1 (en) 2019-12-11 2021-09-07 Sulfateq Bv Compounds for treatment of alzheimer’s disease

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535019A (en) 1978-09-01 1980-03-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS5649378A (en) 1979-08-25 1981-05-02 Otsuka Pharmaceut Co Ltd Tetrazolylalkoxycarbostyril derivative
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
JP2574099B2 (ja) 1992-05-21 1997-01-22 大塚製薬株式会社 アレルギー疾患治療剤
JPH10175864A (ja) 1996-12-16 1998-06-30 Otsuka Pharmaceut Co Ltd 慢性閉塞性肺疾患治療剤
US6428488B1 (en) * 1997-08-28 2002-08-06 Kenneth Kensey Dual riser/dual capillary viscometer for newtonian and non-newtonian fluids
US6322525B1 (en) * 1997-08-28 2001-11-27 Visco Technologies, Inc. Method of analyzing data from a circulating blood viscometer for determining absolute and effective blood viscosity
US6019735A (en) * 1997-08-28 2000-02-01 Visco Technologies, Inc. Viscosity measuring apparatus and method of use
US6322524B1 (en) * 1997-08-28 2001-11-27 Visco Technologies, Inc. Dual riser/single capillary viscometer
ES2237078T3 (es) * 1998-01-16 2005-07-16 Eisai Co., Ltd. Procedimiento para producir derivados de donepezilo.
US6187790B1 (en) * 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
US6484565B2 (en) * 1999-11-12 2002-11-26 Drexel University Single riser/single capillary viscometer using mass detection or column height detection
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
TW200301135A (en) * 2001-12-27 2003-07-01 Otsuka Maryland Res Inst Inc Pharmaceutical compositions comprising a multifunctional phosphodiesterase inhibitor and an adenosine uptake inhibitor
IL150509A (en) * 2002-07-01 2007-07-04 Joseph Kaspi Pharmaceutical preparations containing donafazil hydrochloride
US6743806B2 (en) * 2002-10-23 2004-06-01 Otsuka Pharmaceutical Company, Limited Active oxygen scavenger
FR2848452B1 (fr) * 2002-12-12 2007-04-06 Aventis Pharma Sa Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer
JP2004189706A (ja) * 2002-12-13 2004-07-08 Eisai Co Ltd 高度アルツハイマー型痴呆治療剤
TWI323660B (en) * 2003-02-25 2010-04-21 Otsuka Pharma Co Ltd Pten inhibitor or maxi-k channels opener

Also Published As

Publication number Publication date
AU2008253977B2 (en) 2013-08-22
MX2009012583A (es) 2010-03-08
HRP20150843T1 (hr) 2015-09-11
KR20100020482A (ko) 2010-02-22
EP2937085A1 (en) 2015-10-28
US20100298375A1 (en) 2010-11-25
CA2687289C (en) 2015-09-15
TWI423802B (zh) 2014-01-21
RU2469723C2 (ru) 2012-12-20
WO2008143361A1 (en) 2008-11-27
AU2008253977A1 (en) 2008-11-27
TWI489983B (zh) 2015-07-01
NZ581099A (en) 2012-03-30
RU2009147456A (ru) 2011-06-27
AR066664A1 (es) 2009-09-02
EP2157973B1 (en) 2015-07-15
KR101441725B1 (ko) 2014-09-18
TW200904428A (en) 2009-02-01
JP5153870B2 (ja) 2013-02-27
EP2937085B1 (en) 2019-07-10
CN101754758A (zh) 2010-06-23
PT2157973E (pt) 2015-10-14
IL202053A (en) 2016-04-21
EP2157973A1 (en) 2010-03-03
CO6251249A2 (es) 2011-02-21
BRPI0811919A2 (pt) 2014-11-18
DK2157973T3 (en) 2015-08-17
SI2157973T1 (sl) 2015-10-30
IL202053A0 (en) 2010-06-16
UA96633C2 (uk) 2011-11-25
MY146407A (en) 2012-08-15
TW201412315A (zh) 2014-04-01
CN101754758B (zh) 2012-10-24
PL2157973T3 (pl) 2015-12-31
CA2687289A1 (en) 2008-11-27
CY1116683T1 (el) 2017-03-15
HUE025902T2 (en) 2016-05-30
HK1140422A1 (en) 2010-10-15
ES2545959T3 (es) 2015-09-17
JP2010527993A (ja) 2010-08-19
HK1215384A1 (en) 2016-08-26

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