MX2009012583A - Un medicamento que comprende un derivado de carbostirilo y donepezilo para tratar enfermedad de alzheimer. - Google Patents
Un medicamento que comprende un derivado de carbostirilo y donepezilo para tratar enfermedad de alzheimer.Info
- Publication number
- MX2009012583A MX2009012583A MX2009012583A MX2009012583A MX2009012583A MX 2009012583 A MX2009012583 A MX 2009012583A MX 2009012583 A MX2009012583 A MX 2009012583A MX 2009012583 A MX2009012583 A MX 2009012583A MX 2009012583 A MX2009012583 A MX 2009012583A
- Authority
- MX
- Mexico
- Prior art keywords
- donepezil
- medicament
- disease
- treating alzheimer
- carbostyril derivative
- Prior art date
Links
- ADEBPBSSDYVVLD-UHFFFAOYSA-N donepezil Chemical compound O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 ADEBPBSSDYVVLD-UHFFFAOYSA-N 0.000 title abstract 4
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 229960003530 donepezil Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007135367 | 2007-05-22 | ||
| PCT/JP2008/059763 WO2008143361A1 (en) | 2007-05-22 | 2008-05-21 | A medicament comprising a carbostyril derivative and donepezil for treating alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009012583A true MX2009012583A (es) | 2010-03-08 |
Family
ID=39636992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009012583A MX2009012583A (es) | 2007-05-22 | 2008-05-21 | Un medicamento que comprende un derivado de carbostirilo y donepezilo para tratar enfermedad de alzheimer. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20100298375A1 (enExample) |
| EP (2) | EP2157973B1 (enExample) |
| JP (1) | JP5153870B2 (enExample) |
| KR (1) | KR101441725B1 (enExample) |
| CN (1) | CN101754758B (enExample) |
| AR (1) | AR066664A1 (enExample) |
| AU (1) | AU2008253977B2 (enExample) |
| BR (1) | BRPI0811919A2 (enExample) |
| CA (1) | CA2687289C (enExample) |
| CO (1) | CO6251249A2 (enExample) |
| CY (1) | CY1116683T1 (enExample) |
| DK (1) | DK2157973T3 (enExample) |
| ES (1) | ES2545959T3 (enExample) |
| HR (1) | HRP20150843T1 (enExample) |
| HU (1) | HUE025902T2 (enExample) |
| IL (1) | IL202053A (enExample) |
| MX (1) | MX2009012583A (enExample) |
| MY (1) | MY146407A (enExample) |
| NZ (1) | NZ581099A (enExample) |
| PL (1) | PL2157973T3 (enExample) |
| PT (1) | PT2157973E (enExample) |
| RU (1) | RU2469723C2 (enExample) |
| SI (1) | SI2157973T1 (enExample) |
| TW (2) | TWI423802B (enExample) |
| UA (1) | UA96633C2 (enExample) |
| WO (1) | WO2008143361A1 (enExample) |
| ZA (1) | ZA200908202B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2135607A1 (en) | 2008-06-18 | 2009-12-23 | Pharnext | Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders |
| EP2322163A1 (en) * | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| US9387206B2 (en) | 2009-11-03 | 2016-07-12 | Pharnext | Therapeutic approaches for treating Alzheimer's disease |
| US9241933B2 (en) | 2011-03-01 | 2016-01-26 | Pharnext | Compositions for treating amyotrophic lateral sclerosis |
| US9248111B2 (en) | 2011-03-01 | 2016-02-02 | Pharnext | Therapeutic approaches for treating parkinson's disease |
| US10010515B2 (en) | 2011-03-01 | 2018-07-03 | Pharnext | Therapeutic approaches for treating Parkinson's disease |
| ES2665569T3 (es) | 2011-03-01 | 2018-04-26 | Pharnext | Tratamiento de la isquemia cerebral |
| RU2015101100A (ru) * | 2012-06-15 | 2016-08-10 | Фаундейшн Фор Байомедикал Рисерч Энд Инновейшн | Профилактическое и/или терапевтическое средство для умеренного когнитивного нарушения |
| US20160331922A1 (en) * | 2013-12-23 | 2016-11-17 | John W. Holaday | Disposable container for air hydration |
| EP3459545A4 (en) | 2016-05-19 | 2020-02-26 | National Cerebral and Cardiovascular Center | MEDICATION FOR PREVENTING AND / OR TREATING DEMENTIA |
| CN111032038A (zh) | 2017-05-24 | 2020-04-17 | H.隆德贝克有限公司 | 用于治疗阿尔茨海默氏病的药物组合 |
| CN107602523B (zh) * | 2017-09-11 | 2020-08-18 | 安徽中医药大学 | 京尼平类似物、制备方法及其应用 |
| PL237739B1 (pl) | 2018-06-06 | 2021-05-17 | Univ Gdanski | Genisteina do zastosowania do leczenia choroby Alzheimera |
| NL2024431B1 (en) | 2019-12-11 | 2021-09-07 | Sulfateq Bv | Compounds for treatment of alzheimer’s disease |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535019A (en) | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| JPS5649378A (en) | 1979-08-25 | 1981-05-02 | Otsuka Pharmaceut Co Ltd | Tetrazolylalkoxycarbostyril derivative |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| JP2574099B2 (ja) | 1992-05-21 | 1997-01-22 | 大塚製薬株式会社 | アレルギー疾患治療剤 |
| JPH10175864A (ja) | 1996-12-16 | 1998-06-30 | Otsuka Pharmaceut Co Ltd | 慢性閉塞性肺疾患治療剤 |
| US6428488B1 (en) * | 1997-08-28 | 2002-08-06 | Kenneth Kensey | Dual riser/dual capillary viscometer for newtonian and non-newtonian fluids |
| US6322525B1 (en) * | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Method of analyzing data from a circulating blood viscometer for determining absolute and effective blood viscosity |
| US6019735A (en) * | 1997-08-28 | 2000-02-01 | Visco Technologies, Inc. | Viscosity measuring apparatus and method of use |
| US6322524B1 (en) * | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Dual riser/single capillary viscometer |
| ES2237078T3 (es) * | 1998-01-16 | 2005-07-16 | Eisai Co., Ltd. | Procedimiento para producir derivados de donepezilo. |
| US6187790B1 (en) * | 1999-03-04 | 2001-02-13 | Neal R. Cutler | Use of cilostazol for treatment of sexual dysfunction |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6484565B2 (en) * | 1999-11-12 | 2002-11-26 | Drexel University | Single riser/single capillary viscometer using mass detection or column height detection |
| US6458804B1 (en) * | 2001-01-26 | 2002-10-01 | R.T. Alamo Venturesi, Llc | Methods for the treatment of central nervous system disorders in certain patient groups |
| TW200301135A (en) * | 2001-12-27 | 2003-07-01 | Otsuka Maryland Res Inst Inc | Pharmaceutical compositions comprising a multifunctional phosphodiesterase inhibitor and an adenosine uptake inhibitor |
| IL150509A (en) * | 2002-07-01 | 2007-07-04 | Joseph Kaspi | Pharmaceutical preparations containing donafazil hydrochloride |
| US6743806B2 (en) * | 2002-10-23 | 2004-06-01 | Otsuka Pharmaceutical Company, Limited | Active oxygen scavenger |
| FR2848452B1 (fr) * | 2002-12-12 | 2007-04-06 | Aventis Pharma Sa | Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer |
| JP2004189706A (ja) * | 2002-12-13 | 2004-07-08 | Eisai Co Ltd | 高度アルツハイマー型痴呆治療剤 |
| TWI323660B (en) * | 2003-02-25 | 2010-04-21 | Otsuka Pharma Co Ltd | Pten inhibitor or maxi-k channels opener |
-
2008
- 2008-05-21 US US12/599,962 patent/US20100298375A1/en not_active Abandoned
- 2008-05-21 BR BRPI0811919-8A2A patent/BRPI0811919A2/pt not_active IP Right Cessation
- 2008-05-21 EP EP08764779.8A patent/EP2157973B1/en not_active Not-in-force
- 2008-05-21 PL PL08764779T patent/PL2157973T3/pl unknown
- 2008-05-21 KR KR1020097026651A patent/KR101441725B1/ko not_active Expired - Fee Related
- 2008-05-21 RU RU2009147456/15A patent/RU2469723C2/ru not_active IP Right Cessation
- 2008-05-21 SI SI200831493T patent/SI2157973T1/sl unknown
- 2008-05-21 DK DK08764779.8T patent/DK2157973T3/en active
- 2008-05-21 UA UAA200913247A patent/UA96633C2/uk unknown
- 2008-05-21 PT PT87647798T patent/PT2157973E/pt unknown
- 2008-05-21 HR HRP20150843TT patent/HRP20150843T1/hr unknown
- 2008-05-21 AR ARP080102154A patent/AR066664A1/es unknown
- 2008-05-21 NZ NZ581099A patent/NZ581099A/en not_active IP Right Cessation
- 2008-05-21 MY MYPI20094815A patent/MY146407A/en unknown
- 2008-05-21 AU AU2008253977A patent/AU2008253977B2/en not_active Ceased
- 2008-05-21 CA CA2687289A patent/CA2687289C/en not_active Expired - Fee Related
- 2008-05-21 CN CN2008800167568A patent/CN101754758B/zh not_active Expired - Fee Related
- 2008-05-21 WO PCT/JP2008/059763 patent/WO2008143361A1/en not_active Ceased
- 2008-05-21 TW TW097118634A patent/TWI423802B/zh not_active IP Right Cessation
- 2008-05-21 HU HUE08764779A patent/HUE025902T2/en unknown
- 2008-05-21 MX MX2009012583A patent/MX2009012583A/es active IP Right Grant
- 2008-05-21 JP JP2010509026A patent/JP5153870B2/ja not_active Expired - Fee Related
- 2008-05-21 TW TW102147146A patent/TWI489983B/zh not_active IP Right Cessation
- 2008-05-21 ES ES08764779.8T patent/ES2545959T3/es active Active
- 2008-05-21 EP EP15164200.6A patent/EP2937085B1/en active Active
-
2009
- 2009-11-11 IL IL202053A patent/IL202053A/en not_active IP Right Cessation
- 2009-11-20 ZA ZA200908202A patent/ZA200908202B/xx unknown
- 2009-12-21 CO CO09145995A patent/CO6251249A2/es active IP Right Grant
-
2015
- 2015-09-14 CY CY20151100797T patent/CY1116683T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |