TWI415610B - ３-（４-胺基-１-酮基-１，３-二氫-異吲哚-２-基）-哌啶-２，６-二酮在治療特定白血病之用途 - Google Patents

３-（４-胺基-１-酮基-１，３-二氫-異吲哚-２-基）-哌啶-２，６-二酮在治療特定白血病之用途 Download PDF

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TWI415610B
TWI415610B TW095136901A TW95136901A TWI415610B TW I415610 B TWI415610 B TW I415610B TW 095136901 A TW095136901 A TW 095136901A TW 95136901 A TW95136901 A TW 95136901A TW I415610 B TWI415610 B TW I415610B
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day
leukemia
cancer
amino
dihydro
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TW095136901A
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TW200730175A (en
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Jerome B Zeldis
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Celgene Corp
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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TW095136901A 2005-10-04 2006-10-04 ３-（４-胺基-１-酮基-１，３-二氫-異吲哚-２-基）-哌啶-２，６-二酮在治療特定白血病之用途 TWI415610B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/244,117 US7393862B2 (en) 2002-05-17 2005-10-04 Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias

Publications (2)

Publication Number Publication Date
TW200730175A TW200730175A (en) 2007-08-16
TWI415610B true TWI415610B (zh) 2013-11-21

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Country Status (18)

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US (7) US7393862B2 (https=)
EP (2) EP2526946A1 (https=)
JP (4) JP5916977B2 (https=)
KR (3) KR20080058469A (https=)
CN (2) CN103142594A (https=)
AR (1) AR057868A1 (https=)
AU (1) AU2006299431B2 (https=)
BR (1) BRPI0616670A2 (https=)
CA (2) CA2972299A1 (https=)
IL (1) IL190437A (https=)
NO (1) NO20082068L (https=)
NZ (1) NZ567049A (https=)
PE (1) PE20070761A1 (https=)
RU (2) RU2406501C2 (https=)
TW (1) TWI415610B (https=)
UA (1) UA94062C2 (https=)
WO (1) WO2007041637A2 (https=)
ZA (1) ZA200803700B (https=)

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