TWI362260B - Medicament for preventing and/or treating peripheral neuropathies - Google Patents
Medicament for preventing and/or treating peripheral neuropathies Download PDFInfo
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- TWI362260B TWI362260B TW092130286A TW92130286A TWI362260B TW I362260 B TWI362260 B TW I362260B TW 092130286 A TW092130286 A TW 092130286A TW 92130286 A TW92130286 A TW 92130286A TW I362260 B TWI362260 B TW I362260B
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- acid
- carnitine
- treatment
- pharmaceutically acceptable
- maleate
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
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- A61K31/28—Compounds containing heavy metals
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- A—HUMAN NECESSITIES
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
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- A61K33/243—Platinum; Compounds thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/292,823 US20030199535A1 (en) | 1998-07-30 | 2002-11-13 | Method for preventing and/or treating peripheral neuropathies induced by the administration of an anticancer agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200410683A TW200410683A (en) | 2004-07-01 |
| TWI362260B true TWI362260B (en) | 2012-04-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| TW092130286A TWI362260B (en) | 2002-11-13 | 2003-10-30 | Medicament for preventing and/or treating peripheral neuropathies |
Country Status (19)
| Country | Link |
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| US (2) | US20030199535A1 (https=) |
| EP (1) | EP1562577B1 (https=) |
| JP (1) | JP2006508958A (https=) |
| KR (1) | KR20050075012A (https=) |
| CN (1) | CN1708297A (https=) |
| AR (1) | AR041947A1 (https=) |
| AT (1) | ATE526958T1 (https=) |
| AU (2) | AU2003283807B2 (https=) |
| BR (1) | BR0316131A (https=) |
| CA (1) | CA2505937C (https=) |
| CY (1) | CY1112399T1 (https=) |
| DK (1) | DK1562577T3 (https=) |
| ES (1) | ES2374503T3 (https=) |
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| PL (1) | PL379244A1 (https=) |
| PT (1) | PT1562577E (https=) |
| SI (1) | SI1562577T1 (https=) |
| TW (1) | TWI362260B (https=) |
| WO (1) | WO2004043454A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002313817A1 (en) * | 2001-08-27 | 2003-03-10 | Advanced Cell Technology, Inc. | Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
| DE60330407D1 (de) | 2002-08-23 | 2010-01-14 | Sloan Kettering Inst Cancer | Synthese von Epothilonen, Zwischenprodukte davon, Analoga und ihre Verwendung |
| US6921769B2 (en) | 2002-08-23 | 2005-07-26 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| US7649006B2 (en) | 2002-08-23 | 2010-01-19 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| ITMI20070817A1 (it) * | 2007-04-19 | 2008-10-20 | Farmacetika Ltd | Composizione farmaceutica comprendente l-carnitina ed un agente antagonista dei recettori adenosinici di membrana, loro derivati e/o sali farmaceuticamente accettabili, e uso degli stessi nella preparazione di farmaci con effetto non tossico di inibi |
| JP4208036B1 (ja) * | 2007-04-26 | 2009-01-14 | 日本新薬株式会社 | 抗癌剤投与に伴う末梢神経障害抑制用医薬組成物 |
| CN101790377A (zh) * | 2007-08-31 | 2010-07-28 | 国立大学法人九州大学 | 抗癌剂导致的末梢神经障碍的预防或减轻剂 |
| US20100310674A1 (en) * | 2007-10-30 | 2010-12-09 | Trophos | Novel composition for treating the side effects of anticancer treatments |
| EA201170732A1 (ru) * | 2008-12-01 | 2011-12-30 | Сигма-Тау Индустрие Фармасьютике Риуните С.П.А. | Применение алканоил l-карнитина в комбинации с химиотерапевтическими средствами для лечения новообразований |
| CN102060722B (zh) * | 2009-05-01 | 2014-06-11 | 常州高新技术产业开发区三维工业技术研究所有限公司 | 一种含砷化合物及其制备方法和用途 |
| ITPZ20130005A1 (it) * | 2013-07-05 | 2015-01-06 | Teodosio Antonio Ferrara | Metabolismo energetico e omeostasi |
| WO2018089231A1 (en) | 2016-11-09 | 2018-05-17 | Qiagen Sciences Llc | Photoprotective mixtures as imaging reagents in sequencing-by-synthesis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4713370A (en) * | 1972-11-06 | 1987-12-15 | Felice Stephen L De | Carnitine and its use in reducing cardiac toxicity and as a synergist with cytostats |
| IL74449A (en) * | 1984-03-01 | 1988-07-31 | Us Commerce | Tetrahalo-1,2-cyclohexane-diamino platinum complexes and anti-neoplastic compositions comprising them |
| IT1196564B (it) * | 1986-08-04 | 1988-11-16 | Sigma Tau Ind Farmaceuti | Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche |
| ES2235499T3 (es) * | 1998-07-30 | 2005-07-01 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Uso de derivados de propionil l-carnitina y de acetil l-carnitina en la preparacion de medicamentos con actividad anticancerigena. |
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2002
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- 2003-10-23 ES ES03775788T patent/ES2374503T3/es not_active Expired - Lifetime
- 2003-10-23 EP EP03775788A patent/EP1562577B1/en not_active Expired - Lifetime
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- 2003-10-23 DK DK03775788.7T patent/DK1562577T3/da active
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- 2003-10-23 BR BR0316131-5A patent/BR0316131A/pt not_active IP Right Cessation
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- 2003-10-30 TW TW092130286A patent/TWI362260B/zh not_active IP Right Cessation
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2006
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2009
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2012
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Also Published As
| Publication number | Publication date |
|---|---|
| CN1708297A (zh) | 2005-12-14 |
| BR0316131A (pt) | 2005-09-27 |
| EP1562577B1 (en) | 2011-10-05 |
| PL379244A1 (pl) | 2006-08-07 |
| AU2009201384A1 (en) | 2009-05-07 |
| ATE526958T1 (de) | 2011-10-15 |
| US20060183798A1 (en) | 2006-08-17 |
| CA2505937C (en) | 2011-07-26 |
| DK1562577T3 (da) | 2012-01-23 |
| PT1562577E (pt) | 2012-01-12 |
| SI1562577T1 (sl) | 2012-01-31 |
| AU2003283807A1 (en) | 2004-06-03 |
| AU2003283807B2 (en) | 2009-12-03 |
| CY1112399T1 (el) | 2015-12-09 |
| AR041947A1 (es) | 2005-06-01 |
| CA2505937A1 (en) | 2004-05-27 |
| ES2374503T3 (es) | 2012-02-17 |
| MXPA05004752A (es) | 2005-08-02 |
| US20030199535A1 (en) | 2003-10-23 |
| WO2004043454A1 (en) | 2004-05-27 |
| KR20050075012A (ko) | 2005-07-19 |
| EP1562577A1 (en) | 2005-08-17 |
| JP2006508958A (ja) | 2006-03-16 |
| TW200410683A (en) | 2004-07-01 |
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