TWI353854B - Short duration depot formulations - Google Patents
Short duration depot formulations Download PDFInfo
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- TWI353854B TWI353854B TW92117159A TW92117159A TWI353854B TW I353854 B TWI353854 B TW I353854B TW 92117159 A TW92117159 A TW 92117159A TW 92117159 A TW92117159 A TW 92117159A TW I353854 B TWI353854 B TW I353854B
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- polymer
- gel
- dosage form
- solvent
- agent
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A—HUMAN NECESSITIES
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
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- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B18/00—Use of agglomerated or waste materials or refuse as fillers for mortars, concrete or artificial stone; Treatment of agglomerated or waste materials or refuse, specially adapted to enhance their filling properties in mortars, concrete or artificial stone
- C04B18/04—Waste materials; Refuse
- C04B18/18—Waste materials; Refuse organic
- C04B18/20—Waste materials; Refuse organic from macromolecular compounds
- C04B18/22—Rubber, e.g. ground waste tires
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- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
- C04B28/02—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
- C04B28/04—Portland cements
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
- C04B2111/40—Porous or lightweight materials
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W30/00—Technologies for solid waste management
- Y02W30/50—Reuse, recycling or recovery technologies
- Y02W30/91—Use of waste materials as fillers for mortars or concrete
Landscapes
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ceramic Engineering (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Anesthesiology (AREA)
- Structural Engineering (AREA)
- Materials Engineering (AREA)
- Neurosurgery (AREA)
- Environmental & Geological Engineering (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Civil Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
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| US39186702P | 2002-06-25 | 2002-06-25 |
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| TW200404578A TW200404578A (en) | 2004-04-01 |
| TWI353854B true TWI353854B (en) | 2011-12-11 |
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| TW92117159A TWI353854B (en) | 2002-06-25 | 2003-06-24 | Short duration depot formulations |
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| KR (1) | KR101172721B1 (enExample) |
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| AU (1) | AU2003245643B2 (enExample) |
| BR (1) | BR0312033A (enExample) |
| CA (1) | CA2492047C (enExample) |
| EC (1) | ECSP055566A (enExample) |
| ES (1) | ES2530874T3 (enExample) |
| IL (1) | IL165865A0 (enExample) |
| MA (1) | MA27371A1 (enExample) |
| MX (1) | MXPA05000199A (enExample) |
| NO (1) | NO20050366L (enExample) |
| NZ (1) | NZ574443A (enExample) |
| PL (1) | PL207147B1 (enExample) |
| RU (1) | RU2320321C2 (enExample) |
| TW (1) | TWI353854B (enExample) |
| WO (1) | WO2004000269A1 (enExample) |
| ZA (1) | ZA200500677B (enExample) |
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| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| BR0315304A (pt) | 2002-11-06 | 2005-08-16 | Alza Corp | Formulações com depósito para liberação controlada |
| US20050106214A1 (en) * | 2003-11-14 | 2005-05-19 | Guohua Chen | Excipients in drug delivery vehicles |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| US8658210B2 (en) | 2006-04-17 | 2014-02-25 | Advanced Cardiovascular Systems, Inc. | Polyesteramide platform for site specific drug delivery |
| JP5599705B2 (ja) | 2007-05-18 | 2014-10-01 | デュレクト コーポレーション | 改良されたデポー製剤 |
| CA2687979C (en) | 2007-05-25 | 2017-07-04 | Tolmar Therapeutics, Inc. | Sustained delivery formulations of risperidone compounds |
| US8846068B2 (en) * | 2008-04-18 | 2014-09-30 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising a local anesthetic |
| RS60051B1 (sr) * | 2011-06-10 | 2020-04-30 | Ramscor Inc | Formulacije sa produženim oslobađanjem za isporuku proteina u oko i postupci njihove pripreme |
| US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
| CN109602692B (zh) | 2013-03-11 | 2022-11-04 | 度瑞公司 | 包含高粘度液体载体的可注射控制释放组合物 |
| CN105764491A (zh) | 2013-12-09 | 2016-07-13 | 度瑞公司 | 药物活性剂复合物、聚合物复合物，以及包括其的组合物和方法 |
| KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
| CN111388406B (zh) * | 2020-03-24 | 2024-02-23 | 西安力邦医药科技有限责任公司 | 氟维司群或其衍生物可注射递药贮库及其制备方法和应用 |
| KR20230145053A (ko) | 2021-01-12 | 2023-10-17 | 듀렉트 코퍼레이션 | 지속 방출 약물 전달 시스템 및 관련 방법 |
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| US3797492A (en) | 1972-12-27 | 1974-03-19 | Alza Corp | Device for dispensing product with directional guidance member |
| US3987790A (en) | 1975-10-01 | 1976-10-26 | Alza Corporation | Osmotically driven fluid dispenser |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4443340A (en) | 1981-10-09 | 1984-04-17 | Betz Laboratories, Inc. | Control of iron induced fouling in water systems |
| US4985404A (en) | 1984-10-04 | 1991-01-15 | Monsanto Company | Prolonged release of biologically active polypeptides |
| US4865845A (en) | 1986-03-21 | 1989-09-12 | Alza Corporation | Release rate adjustment of osmotic or diffusional delivery devices |
| US4853218A (en) | 1987-02-24 | 1989-08-01 | Schering Corporation | Zinc-protamine-alpha interferon complex |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US5085866A (en) | 1988-12-02 | 1992-02-04 | Southern Research Institute | Method of producing zero-order controlled-released devices |
| US5059423A (en) | 1988-12-13 | 1991-10-22 | Alza Corporation | Delivery system comprising biocompatible beneficial agent formulation |
| US5057318A (en) | 1988-12-13 | 1991-10-15 | Alza Corporation | Delivery system for beneficial agent over a broad range of rates |
| US5324519A (en) | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US5112614A (en) | 1989-09-14 | 1992-05-12 | Alza Corporation | Implantable delivery dispenser |
| US5234693A (en) | 1990-07-11 | 1993-08-10 | Alza Corporation | Delivery device with a protective sleeve |
| US5234692A (en) | 1990-07-11 | 1993-08-10 | Alza Corporation | Delivery device with a protective sleeve |
| US5151093A (en) | 1990-10-29 | 1992-09-29 | Alza Corporation | Osmotically driven syringe with programmable agent delivery |
| US5620700A (en) | 1990-10-30 | 1997-04-15 | Alza Corporation | Injectable drug delivery system and method |
| GB9027422D0 (en) | 1990-12-18 | 1991-02-06 | Scras | Osmotically driven infusion device |
| US5137727A (en) | 1991-06-12 | 1992-08-11 | Alza Corporation | Delivery device providing beneficial agent stability |
| US5288214A (en) | 1991-09-30 | 1994-02-22 | Toshio Fukuda | Micropump |
| KR970007322B1 (ko) | 1991-12-19 | 1997-05-07 | 미쓰이도오아쓰 가가쿠 가부시키가이샤 | 폴리히드록시 카르복실산 및 그 제조방법 |
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-
2003
- 2003-06-24 AR ARP030102261 patent/AR039729A1/es not_active Application Discontinuation
- 2003-06-24 TW TW92117159A patent/TWI353854B/zh not_active IP Right Cessation
- 2003-06-25 EP EP20100013179 patent/EP2311431A1/en not_active Withdrawn
- 2003-06-25 AU AU2003245643A patent/AU2003245643B2/en not_active Ceased
- 2003-06-25 BR BR0312033A patent/BR0312033A/pt not_active Application Discontinuation
- 2003-06-25 RU RU2005101640A patent/RU2320321C2/ru not_active IP Right Cessation
- 2003-06-25 IL IL16586503A patent/IL165865A0/xx unknown
- 2003-06-25 MX MXPA05000199A patent/MXPA05000199A/es active IP Right Grant
- 2003-06-25 ES ES03739271T patent/ES2530874T3/es not_active Expired - Lifetime
- 2003-06-25 EP EP20030739271 patent/EP1515697B1/en not_active Expired - Lifetime
- 2003-06-25 CN CN038176122A patent/CN1671357B/zh not_active Expired - Fee Related
- 2003-06-25 WO PCT/US2003/019762 patent/WO2004000269A1/en not_active Ceased
- 2003-06-25 PL PL373123A patent/PL207147B1/pl unknown
- 2003-06-25 NZ NZ574443A patent/NZ574443A/en not_active IP Right Cessation
- 2003-06-25 KR KR20047021001A patent/KR101172721B1/ko not_active Expired - Fee Related
- 2003-06-25 JP JP2004516150A patent/JP2005533081A/ja not_active Withdrawn
- 2003-06-25 CA CA2492047A patent/CA2492047C/en not_active Expired - Fee Related
- 2003-06-25 EP EP20100013092 patent/EP2316421A1/en not_active Withdrawn
-
2005
- 2005-01-24 ZA ZA200500677A patent/ZA200500677B/xx unknown
- 2005-01-24 MA MA28060A patent/MA27371A1/fr unknown
- 2005-01-24 NO NO20050366A patent/NO20050366L/no not_active Application Discontinuation
- 2005-01-24 EC ECSP055566 patent/ECSP055566A/es unknown
-
2010
- 2010-12-03 JP JP2010270394A patent/JP5631708B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO20050366L (no) | 2005-03-23 |
| PL207147B1 (pl) | 2010-11-30 |
| CN1671357A (zh) | 2005-09-21 |
| CA2492047C (en) | 2014-08-12 |
| MA27371A1 (fr) | 2005-06-01 |
| RU2005101640A (ru) | 2005-08-10 |
| WO2004000269A1 (en) | 2003-12-31 |
| ZA200500677B (en) | 2006-08-30 |
| AR039729A1 (es) | 2005-03-09 |
| BR0312033A (pt) | 2005-04-26 |
| TW200404578A (en) | 2004-04-01 |
| EP1515697B1 (en) | 2014-11-19 |
| ECSP055566A (es) | 2005-04-18 |
| CN1671357B (zh) | 2010-08-11 |
| ES2530874T3 (es) | 2015-03-06 |
| KR20050026414A (ko) | 2005-03-15 |
| MXPA05000199A (es) | 2005-06-06 |
| KR101172721B1 (ko) | 2012-08-30 |
| CA2492047A1 (en) | 2003-12-31 |
| IL165865A0 (en) | 2006-01-15 |
| EP2311431A1 (en) | 2011-04-20 |
| AU2003245643A1 (en) | 2004-01-06 |
| EP2316421A1 (en) | 2011-05-04 |
| JP2011068670A (ja) | 2011-04-07 |
| HK1082412A1 (en) | 2006-06-09 |
| PL373123A1 (en) | 2005-08-08 |
| NZ574443A (en) | 2010-08-27 |
| JP2005533081A (ja) | 2005-11-04 |
| RU2320321C2 (ru) | 2008-03-27 |
| JP5631708B2 (ja) | 2014-11-26 |
| AU2003245643B2 (en) | 2009-02-26 |
| EP1515697A1 (en) | 2005-03-23 |
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| MM4A | Annulment or lapse of patent due to non-payment of fees |