CN1671357B - 短暂贮存制剂 - Google Patents

短暂贮存制剂 Download PDF

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Publication number
CN1671357B
CN1671357B CN038176122A CN03817612A CN1671357B CN 1671357 B CN1671357 B CN 1671357B CN 038176122 A CN038176122 A CN 038176122A CN 03817612 A CN03817612 A CN 03817612A CN 1671357 B CN1671357 B CN 1671357B
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CN
China
Prior art keywords
polymer
gel
solvent
weight
sustained release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN038176122A
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English (en)
Chinese (zh)
Other versions
CN1671357A (zh
Inventor
陈国华
D·普莱比
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CN1671357A publication Critical patent/CN1671357A/zh
Application granted granted Critical
Publication of CN1671357B publication Critical patent/CN1671357B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B18/00—Use of agglomerated or waste materials or refuse as fillers for mortars, concrete or artificial stone; Treatment of agglomerated or waste materials or refuse, specially adapted to enhance their filling properties in mortars, concrete or artificial stone
    • C04B18/04—Waste materials; Refuse
    • C04B18/18—Waste materials; Refuse organic
    • C04B18/20—Waste materials; Refuse organic from macromolecular compounds
    • C04B18/22—Rubber, e.g. ground waste tires
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/02—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
    • C04B28/04—Portland cements
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/40—Porous or lightweight materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W30/00—Technologies for solid waste management
    • Y02W30/50—Reuse, recycling or recovery technologies
    • Y02W30/91—Use of waste materials as fillers for mortars or concrete

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Structural Engineering (AREA)
  • Materials Engineering (AREA)
  • Neurosurgery (AREA)
  • Environmental & Geological Engineering (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Civil Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN038176122A 2002-06-25 2003-06-25 短暂贮存制剂 Expired - Fee Related CN1671357B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39186702P 2002-06-25 2002-06-25
US60/391,867 2002-06-25
PCT/US2003/019762 WO2004000269A1 (en) 2002-06-25 2003-06-25 Short duration depot formulations

Publications (2)

Publication Number Publication Date
CN1671357A CN1671357A (zh) 2005-09-21
CN1671357B true CN1671357B (zh) 2010-08-11

Family

ID=30000765

Family Applications (1)

Application Number Title Priority Date Filing Date
CN038176122A Expired - Fee Related CN1671357B (zh) 2002-06-25 2003-06-25 短暂贮存制剂

Country Status (20)

Country Link
EP (3) EP2311431A1 (enExample)
JP (2) JP2005533081A (enExample)
KR (1) KR101172721B1 (enExample)
CN (1) CN1671357B (enExample)
AR (1) AR039729A1 (enExample)
AU (1) AU2003245643B2 (enExample)
BR (1) BR0312033A (enExample)
CA (1) CA2492047C (enExample)
EC (1) ECSP055566A (enExample)
ES (1) ES2530874T3 (enExample)
IL (1) IL165865A0 (enExample)
MA (1) MA27371A1 (enExample)
MX (1) MXPA05000199A (enExample)
NO (1) NO20050366L (enExample)
NZ (1) NZ574443A (enExample)
PL (1) PL207147B1 (enExample)
RU (1) RU2320321C2 (enExample)
TW (1) TWI353854B (enExample)
WO (1) WO2004000269A1 (enExample)
ZA (1) ZA200500677B (enExample)

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US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
BR0315304A (pt) 2002-11-06 2005-08-16 Alza Corp Formulações com depósito para liberação controlada
US20050106214A1 (en) * 2003-11-14 2005-05-19 Guohua Chen Excipients in drug delivery vehicles
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
US8658210B2 (en) 2006-04-17 2014-02-25 Advanced Cardiovascular Systems, Inc. Polyesteramide platform for site specific drug delivery
JP5599705B2 (ja) 2007-05-18 2014-10-01 デュレクト コーポレーション 改良されたデポー製剤
CA2687979C (en) 2007-05-25 2017-07-04 Tolmar Therapeutics, Inc. Sustained delivery formulations of risperidone compounds
US8846068B2 (en) * 2008-04-18 2014-09-30 Warsaw Orthopedic, Inc. Methods and compositions for treating post-operative pain comprising a local anesthetic
RS60051B1 (sr) * 2011-06-10 2020-04-30 Ramscor Inc Formulacije sa produženim oslobađanjem za isporuku proteina u oko i postupci njihove pripreme
US20140308352A1 (en) 2013-03-11 2014-10-16 Zogenix Inc. Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material
CN109602692B (zh) 2013-03-11 2022-11-04 度瑞公司 包含高粘度液体载体的可注射控制释放组合物
CN105764491A (zh) 2013-12-09 2016-07-13 度瑞公司 药物活性剂复合物、聚合物复合物，以及包括其的组合物和方法
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
CN111388406B (zh) * 2020-03-24 2024-02-23 西安力邦医药科技有限责任公司 氟维司群或其衍生物可注射递药贮库及其制备方法和应用
KR20230145053A (ko) 2021-01-12 2023-10-17 듀렉트 코퍼레이션 지속 방출 약물 전달 시스템 및 관련 방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1240346A (zh) * 1996-12-20 2000-01-05 阿尔萨公司 凝胶组合物及方法

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Also Published As

Publication number Publication date
NO20050366L (no) 2005-03-23
TWI353854B (en) 2011-12-11
PL207147B1 (pl) 2010-11-30
CN1671357A (zh) 2005-09-21
CA2492047C (en) 2014-08-12
MA27371A1 (fr) 2005-06-01
RU2005101640A (ru) 2005-08-10
WO2004000269A1 (en) 2003-12-31
ZA200500677B (en) 2006-08-30
AR039729A1 (es) 2005-03-09
BR0312033A (pt) 2005-04-26
TW200404578A (en) 2004-04-01
EP1515697B1 (en) 2014-11-19
ECSP055566A (es) 2005-04-18
ES2530874T3 (es) 2015-03-06
KR20050026414A (ko) 2005-03-15
MXPA05000199A (es) 2005-06-06
KR101172721B1 (ko) 2012-08-30
CA2492047A1 (en) 2003-12-31
IL165865A0 (en) 2006-01-15
EP2311431A1 (en) 2011-04-20
AU2003245643A1 (en) 2004-01-06
EP2316421A1 (en) 2011-05-04
JP2011068670A (ja) 2011-04-07
HK1082412A1 (en) 2006-06-09
PL373123A1 (en) 2005-08-08
NZ574443A (en) 2010-08-27
JP2005533081A (ja) 2005-11-04
RU2320321C2 (ru) 2008-03-27
JP5631708B2 (ja) 2014-11-26
AU2003245643B2 (en) 2009-02-26
EP1515697A1 (en) 2005-03-23

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