TWI283666B - Piperidine derivatives useful as CCR5 antagonists - Google Patents
Piperidine derivatives useful as CCR5 antagonists Download PDFInfo
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- TWI283666B TWI283666B TW089108325A TW89108325A TWI283666B TW I283666 B TWI283666 B TW I283666B TW 089108325 A TW089108325 A TW 089108325A TW 89108325 A TW89108325 A TW 89108325A TW I283666 B TWI283666 B TW I283666B
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Classifications
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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| US30518799A | 1999-05-04 | 1999-05-04 |
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| TWI283666B true TWI283666B (en) | 2007-07-11 |
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| TW089108325A TWI283666B (en) | 1999-05-04 | 2000-05-02 | Piperidine derivatives useful as CCR5 antagonists |
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| US11629196B2 (en) | 2020-04-27 | 2023-04-18 | Incelldx, Inc. | Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676054B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| US5889006A (en) * | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
| ES2182104T3 (es) * | 1996-07-10 | 2003-03-01 | Schering Corp | Piperidinas 1,4-disustituidas como antagonistas muscarinicos. |
| AU6623796A (en) * | 1996-07-25 | 1998-02-20 | Terence George Mackay | Improvements in or relating to fishing |
| HUP9904363A3 (en) * | 1996-08-15 | 2000-12-28 | Schering Corp | Piperidine ether muscarinic antagonists and pharmaceutical compositions containing them |
| WO1999004794A1 (en) * | 1997-07-25 | 1999-02-04 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
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2000
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