TWI272914B - Additives for crustacean or fish feeds and feeds - Google Patents
Additives for crustacean or fish feeds and feeds Download PDFInfo
- Publication number
- TWI272914B TWI272914B TW089105420A TW89105420A TWI272914B TW I272914 B TWI272914 B TW I272914B TW 089105420 A TW089105420 A TW 089105420A TW 89105420 A TW89105420 A TW 89105420A TW I272914 B TWI272914 B TW I272914B
- Authority
- TW
- Taiwan
- Prior art keywords
- molecular weight
- fish
- group
- crustaceans
- lipopolysaccharide
- Prior art date
Links
- 241000251468 Actinopterygii Species 0.000 title claims abstract description 67
- 241000238424 Crustacea Species 0.000 title claims abstract description 54
- 239000000654 additive Substances 0.000 title abstract description 8
- 239000002158 endotoxin Substances 0.000 claims abstract description 115
- 229920006008 lipopolysaccharide Polymers 0.000 claims abstract description 115
- 208000015181 infectious disease Diseases 0.000 claims abstract description 22
- 238000000034 method Methods 0.000 claims abstract description 21
- 230000000813 microbial effect Effects 0.000 claims abstract description 16
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 claims abstract description 7
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 6
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 6
- 239000004480 active ingredient Substances 0.000 claims abstract description 4
- 201000010099 disease Diseases 0.000 claims description 26
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 26
- 239000003674 animal food additive Substances 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 230000002265 prevention Effects 0.000 claims description 9
- 206010036790 Productive cough Diseases 0.000 claims description 8
- 210000003802 sputum Anatomy 0.000 claims description 8
- 208000024794 sputum Diseases 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 208000035143 Bacterial infection Diseases 0.000 claims description 6
- 230000001154 acute effect Effects 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 230000000069 prophylactic effect Effects 0.000 claims description 5
- 208000035473 Communicable disease Diseases 0.000 claims description 4
- 241000520272 Pantoea Species 0.000 claims description 4
- 206010047400 Vibrio infections Diseases 0.000 claims description 4
- 206010058874 Viraemia Diseases 0.000 claims description 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 4
- 230000017074 necrotic cell death Effects 0.000 claims description 4
- 230000009385 viral infection Effects 0.000 claims description 4
- 244000005700 microbiome Species 0.000 claims description 3
- 208000031888 Mycoses Diseases 0.000 claims description 2
- 239000000969 carrier Substances 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 230000003394 haemopoietic effect Effects 0.000 claims description 2
- 230000005934 immune activation Effects 0.000 claims description 2
- 230000002458 infectious effect Effects 0.000 claims description 2
- 238000002372 labelling Methods 0.000 claims 2
- 208000030852 Parasitic disease Diseases 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 16
- 230000002434 immunopotentiative effect Effects 0.000 abstract 1
- 241000238557 Decapoda Species 0.000 description 24
- 238000012360 testing method Methods 0.000 description 22
- 210000004027 cell Anatomy 0.000 description 19
- 230000036737 immune function Effects 0.000 description 13
- 239000000126 substance Substances 0.000 description 12
- 210000000601 blood cell Anatomy 0.000 description 11
- 239000000047 product Substances 0.000 description 11
- 210000000265 leukocyte Anatomy 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- MSFSPUZXLOGKHJ-UHFFFAOYSA-N Muraminsaeure Natural products OC(=O)C(C)OC1C(N)C(O)OC(CO)C1O MSFSPUZXLOGKHJ-UHFFFAOYSA-N 0.000 description 7
- 108010013639 Peptidoglycan Proteins 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 6
- 230000002079 cooperative effect Effects 0.000 description 6
- 241000700605 Viruses Species 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 238000005119 centrifugation Methods 0.000 description 5
- 230000034994 death Effects 0.000 description 5
- 229960003964 deoxycholic acid Drugs 0.000 description 5
- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 description 5
- 239000002689 soil Substances 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 241000238366 Cephalopoda Species 0.000 description 4
- 241000252233 Cyprinus carpio Species 0.000 description 4
- 241000048284 Potato virus P Species 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 239000012153 distilled water Substances 0.000 description 4
- 238000011081 inoculation Methods 0.000 description 4
- 238000000108 ultra-filtration Methods 0.000 description 4
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 3
- 241000237519 Bivalvia Species 0.000 description 3
- 241000282320 Panthera leo Species 0.000 description 3
- 239000012614 Q-Sepharose Substances 0.000 description 3
- 102000003425 Tyrosinase Human genes 0.000 description 3
- 108060008724 Tyrosinase Proteins 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 3
- 230000036528 appetite Effects 0.000 description 3
- 235000019789 appetite Nutrition 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 235000020639 clam Nutrition 0.000 description 3
- 230000007123 defense Effects 0.000 description 3
- 238000004090 dissolution Methods 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000003449 preventive effect Effects 0.000 description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 230000003612 virological effect Effects 0.000 description 3
- 241000186000 Bifidobacterium Species 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 241000192125 Firmicutes Species 0.000 description 2
- 241000194040 Lactococcus garvieae Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 206010028851 Necrosis Diseases 0.000 description 2
- 241000588912 Pantoea agglomerans Species 0.000 description 2
- 241000927735 Penaeus Species 0.000 description 2
- 241000589516 Pseudomonas Species 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 241000222480 Schizophyllum Species 0.000 description 2
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 238000005571 anion exchange chromatography Methods 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 239000006285 cell suspension Substances 0.000 description 2
- 210000002421 cell wall Anatomy 0.000 description 2
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 2
- 238000011033 desalting Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 239000003640 drug residue Substances 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 238000002523 gelfiltration Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 230000001900 immune effect Effects 0.000 description 2
- 238000011068 loading method Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000007170 pathology Effects 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 239000013535 sea water Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 239000012312 sodium hydride Substances 0.000 description 2
- 229910000104 sodium hydride Inorganic materials 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 229940126585 therapeutic drug Drugs 0.000 description 2
- 102000003390 tumor necrosis factor Human genes 0.000 description 2
- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 241000607534 Aeromonas Species 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241001674044 Blattodea Species 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
- 241000588914 Enterobacter Species 0.000 description 1
- 241000194031 Enterococcus faecium Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000907635 Farfantepenaeus duorarum Species 0.000 description 1
- 241000995704 Fenneropenaeus chinensis Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010020850 Hyperthyroidism Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 description 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 description 1
- 241000235428 Lagenidium Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 240000008790 Musa x paradisiaca Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 241001595185 Neoeriocheir leptognathus Species 0.000 description 1
- 241001327682 Oncorhynchus mykiss irideus Species 0.000 description 1
- 108700022034 Opsonin Proteins Proteins 0.000 description 1
- 230000010718 Oxidation Activity Effects 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 244000290889 Phoenix sylvestris Species 0.000 description 1
- 241000269908 Platichthys flesus Species 0.000 description 1
- 241000861914 Plecoglossus altivelis Species 0.000 description 1
- 241001098666 Pterois volitans Species 0.000 description 1
- 244000184734 Pyrus japonica Species 0.000 description 1
- 241001080167 Salatis Species 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241000239226 Scorpiones Species 0.000 description 1
- 239000012506 Sephacryl® Substances 0.000 description 1
- 241000607720 Serratia Species 0.000 description 1
- 241001441724 Tetraodontidae Species 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 210000003489 abdominal muscle Anatomy 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003957 anion exchange resin Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 238000009360 aquaculture Methods 0.000 description 1
- 244000144974 aquaculture Species 0.000 description 1
- 210000003651 basophil Anatomy 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 210000004748 cultured cell Anatomy 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 230000008260 defense mechanism Effects 0.000 description 1
- 238000011026 diafiltration Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- YLQWCDOCJODRMT-UHFFFAOYSA-N fluoren-9-one Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3C2=C1 YLQWCDOCJODRMT-UHFFFAOYSA-N 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 238000002309 gasification Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 239000010903 husk Substances 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000003308 immunostimulating effect Effects 0.000 description 1
- -1 ingots Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 241000238565 lobster Species 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 210000000440 neutrophil Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000011076 safety test Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 239000002795 scorpion venom Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- PNYYBUOBTVHFDN-UHFFFAOYSA-N sodium bismuthate Chemical compound [Na+].[O-][Bi](=O)=O PNYYBUOBTVHFDN-UHFFFAOYSA-N 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000011537 solubilization buffer Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000005496 tempering Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/739—Lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Animal Husbandry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Birds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8439999 | 1999-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TWI272914B true TWI272914B (en) | 2007-02-11 |
Family
ID=13829510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW089105420A TWI272914B (en) | 1999-03-26 | 2000-03-24 | Additives for crustacean or fish feeds and feeds |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1082908B1 (https=) |
| KR (1) | KR20010071331A (https=) |
| CN (1) | CN100473284C (https=) |
| AT (1) | ATE440502T1 (https=) |
| AU (1) | AU757122C (https=) |
| CA (1) | CA2333160C (https=) |
| DE (1) | DE60042807D1 (https=) |
| ES (1) | ES2330300T3 (https=) |
| TW (1) | TWI272914B (https=) |
| WO (1) | WO2000057719A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100483911B1 (ko) * | 2001-05-14 | 2005-04-18 | 주식회사 메디오젠 | 양식어류의 면역증강과 항병력강화 및 증체를 위한 사료첨가제 |
| US8075928B2 (en) | 2003-09-26 | 2011-12-13 | Gen-Ichiro Soma | Method for fermentation and cultivation, fermented plant extract, fermented plant extract powder, and composition containing the extract of fermented plant |
| WO2005084704A1 (en) * | 2004-03-02 | 2005-09-15 | Peros Systems Technologies Inc. | Digestive bypass composition for arthropod and uses thereof |
| NO339169B1 (no) * | 2008-04-24 | 2016-11-14 | Chemoforma Ltd | Funksjonelt fiskefôr omfattende peptidoglykan og nukleotider |
| FI20085812A0 (fi) * | 2008-09-01 | 2008-09-01 | Esa-Matti Lilius | Karkea LPS immunostimulanttina vesiviljelyssä |
| CN101461940B (zh) * | 2009-01-09 | 2011-01-26 | 中国水产科学研究所南海水产研究所 | 美人鱼发光杆菌疫苗及其制备方法和应用 |
| KR101040186B1 (ko) * | 2009-10-12 | 2011-06-09 | 주식회사 진우씨스템 | 배선덕트 커버 |
| KR101519506B1 (ko) | 2012-06-07 | 2015-05-18 | 주식회사제이엔비바이오 | 새우사료 첨가제 조성물 및 그 제조방법 |
| JP6246517B2 (ja) * | 2013-07-26 | 2017-12-13 | 克史 小早川 | 飲料水 |
| KR101854016B1 (ko) | 2015-11-13 | 2018-06-20 | 주식회사 네오엔비즈 | 바이오플락 유용유기물을 포함하는 사료첨가제와 그 생산방법 |
| KR101857327B1 (ko) | 2015-11-16 | 2018-06-19 | 주식회사 네오엔비즈 | 바이오 플락 양식과정에서 생산되는 유용유기물을 원료로 포함하는 사료 및 사료제조방법 |
| CN108552435A (zh) * | 2018-04-12 | 2018-09-21 | 福建高农饲料有限公司 | 高体鰤鱼人工配合饲料及其制备方法 |
| EP4152948A4 (en) * | 2020-06-26 | 2024-08-07 | Zivo Bioscience, Inc. | IMMUNE PRIMING TO ACCELERATE/ENHANCE THE IMMUNE RESPONSE BY ADMINISTRATION OF A NATURAL IMMUNE MODULATOR |
| BR112022026479A2 (pt) * | 2020-06-26 | 2024-03-05 | Zivo Bioscience Inc | Preparação imune para acelerar/aprimorar a resposta imune por meio da administração de modulador imune natural |
| US12599657B2 (en) * | 2020-07-02 | 2026-04-14 | Zivo Bioscience, Inc. | Enhancement of vaccine efficacy via biomass and/or related material in animal drink and feed |
| CN113647516A (zh) * | 2021-07-26 | 2021-11-16 | 中农科生物工程技术(苏州)有限公司 | 链壶菌诱抗蛋白质LiiP1的制备方法及应用 |
| CN115029267B (zh) * | 2022-06-20 | 2022-12-27 | 聚芯生物工程有限公司 | 一种对虾用抗病促生长的复合型饲料添加剂及其应用 |
| WO2026008873A1 (en) | 2024-07-04 | 2026-01-08 | Microharvest Gmbh | Feed compositions comprising microbial biomass for fish, crustaceans and/or cephalopods |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2049548C (en) * | 1990-08-20 | 2002-07-02 | Kiyoshi Yoshimura | Lps-producing bacteria, lpss, and lps-containing medicines and veterinary medicines |
| TW391878B (en) * | 1992-10-07 | 2000-06-01 | Eisai Co Ltd | Pharmaceutical composition or feedstuff comprising at least one of rosa roxburghii, artemisiae argyi folium and brassica oleracea var. capitata l. |
| JPH06141849A (ja) * | 1992-10-30 | 1994-05-24 | Genichiro Soma | Ｌｐｓ産生菌、ｌｐｓ、免疫機能活性化剤及び動物用免疫機能活性化剤 |
| JP4043533B2 (ja) * | 1995-01-27 | 2008-02-06 | 水野 傳一 | 低分子量リポポリサッカライド |
| JPH08280332A (ja) * | 1995-04-18 | 1996-10-29 | Natl Fedelation Of Agricult Coop Assoc | 飼料用添加剤 |
| JPH10279486A (ja) * | 1997-04-02 | 1998-10-20 | Taiyo Kagaku Co Ltd | 免疫賦活組成物 |
-
2000
- 2000-03-23 CA CA002333160A patent/CA2333160C/en not_active Expired - Lifetime
- 2000-03-23 KR KR1020007013326A patent/KR20010071331A/ko active Granted
- 2000-03-23 WO PCT/JP2000/001764 patent/WO2000057719A1/ja not_active Ceased
- 2000-03-23 CN CNB00800398XA patent/CN100473284C/zh not_active Expired - Lifetime
- 2000-03-23 AU AU33257/00A patent/AU757122C/en not_active Expired
- 2000-03-23 AT AT00911297T patent/ATE440502T1/de not_active IP Right Cessation
- 2000-03-23 ES ES00911297T patent/ES2330300T3/es not_active Expired - Lifetime
- 2000-03-23 EP EP00911297A patent/EP1082908B1/en not_active Expired - Lifetime
- 2000-03-23 DE DE60042807T patent/DE60042807D1/de not_active Expired - Fee Related
- 2000-03-24 TW TW089105420A patent/TWI272914B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE440502T1 (de) | 2009-09-15 |
| CN1306399A (zh) | 2001-08-01 |
| ES2330300T3 (es) | 2009-12-09 |
| KR20010071331A (ko) | 2001-07-28 |
| AU3325700A (en) | 2000-10-16 |
| CA2333160C (en) | 2005-10-18 |
| DE60042807D1 (de) | 2009-10-08 |
| CN100473284C (zh) | 2009-04-01 |
| AU757122C (en) | 2004-11-25 |
| WO2000057719A1 (fr) | 2000-10-05 |
| EP1082908A4 (en) | 2004-10-13 |
| CA2333160A1 (en) | 2000-10-05 |
| KR100400352B1 (https=) | 2003-10-04 |
| EP1082908A1 (en) | 2001-03-14 |
| EP1082908B1 (en) | 2009-08-26 |
| AU757122B2 (en) | 2003-02-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI272914B (en) | Additives for crustacean or fish feeds and feeds | |
| Maeda et al. | Antitumor effects of various low-molecular-weight chitosans are due to increased natural killer activity of intestinal intraepithelial lymphocytes in sarcoma 180–bearing mice | |
| KR20120031522A (ko) | 발효 및 배양 방법, 식물발효 엑기스, 식물발효 엑기스 분말 및 이 식물발효 엑기스 배합물 | |
| KR20150024115A (ko) | 바실러스 서브틸러스 및 파지 혼합물을 유효성분으로 함유하는 어류용 프로바이오틱스 조성물 | |
| CN114480302B (zh) | 一株海藻希瓦氏菌噬菌体、其噬菌体组合物及其应用 | |
| Yazhiniprabha et al. | The dietary supplementation of zinc oxide and selenium nanoparticles enhance the immune response in freshwater fish Oreochromis mossambicus against aquatic pathogen Aeromonas hydrophila | |
| Balachandran et al. | A study on the effect of using mangrove leaf extracts as a feed additive in the progress of bacterial infections in marine ornamental fish | |
| CN109486732B (zh) | 一种长双歧杆菌及其应用 | |
| CN113598285A (zh) | 一种提高水产养殖动物肠道免疫的中药发酵饲料及其制备方法 | |
| JP2005220065A (ja) | 免疫賦活剤 | |
| CN114456969A (zh) | 一种用于减肥降血糖的益生菌制剂及其制备方法和应用 | |
| CN116606761B (zh) | 一种能够缓解类风湿性关节炎的动物双歧杆菌乳亚种BLa19及其应用 | |
| CN118593549A (zh) | 嗜酸乳杆菌与表没食子儿茶素没食子酸酯联用在制备抗畜禽大肠杆菌病药物中的应用 | |
| US10889608B2 (en) | Ester of aminoglycan and uses thereof | |
| TWI716249B (zh) | 戈氏副擬桿菌的脂多醣用於抑制發炎反應之用途 | |
| JP3665850B2 (ja) | 免疫賦活剤 | |
| CN115247155B (zh) | 一株美人鱼发光杆菌噬菌体、其噬菌体组合物及其应用 | |
| CN119791206B (zh) | 一种利用壳寡糖制备的复合微生态制剂及其应用 | |
| Sandeepa et al. | Immunological and Antioxidant Response of Litopenaeus vannamei fed with Lactobacillus species under WSSV challenge | |
| TWI757012B (zh) | 一種用於預防水產動物受病原體感染富含合益素及適口性佳之飼料添加物 | |
| AL-Ghanmi | Effect of Bacillus subtilis on microbial community, growth performance, and some haemato-immunological parameters of common carp (Cyprinus carpio) | |
| KR20240110171A (ko) | 지방세포의 지방축적 억제능을 갖는 Lactobacillus reuteri KCL018 균주, 이의 배양액 또는 균체 추출물을 포함하는 조성물 | |
| CN120905098A (zh) | 一株增强免疫调节功能的短双歧杆菌及其应用 | |
| WO2025225662A1 (ja) | 免疫賦活用組成物及び免疫賦活方法 | |
| KR20240110172A (ko) | 지방세포의 지방축적 억제능을 갖는 Lactobacillus pentosus KCL032 균주, 이의 배양액 또는 균체 추출물을 포함하는 조성물 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |