TW260669B - - Google Patents

Info

Publication number
TW260669B
TW260669B TW083101366A TW83101366A TW260669B TW 260669 B TW260669 B TW 260669B TW 083101366 A TW083101366 A TW 083101366A TW 83101366 A TW83101366 A TW 83101366A TW 260669 B TW260669 B TW 260669B
Authority
TW
Taiwan
Prior art keywords
alkyl
suitable substituent
pct
hydrogen
heterocyclic group
Prior art date
Application number
TW083101366A
Other languages
English (en)
Chinese (zh)
Original Assignee
Fujisawa Yakusin Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Yakusin Kogyo Kk filed Critical Fujisawa Yakusin Kogyo Kk
Application granted granted Critical
Publication of TW260669B publication Critical patent/TW260669B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
TW083101366A 1993-02-26 1994-02-18 TW260669B (OSRAM)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939303993A GB9303993D0 (en) 1993-02-26 1993-02-26 New heterocyclic derivatives

Publications (1)

Publication Number Publication Date
TW260669B true TW260669B (OSRAM) 1995-10-21

Family

ID=10731142

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083101366A TW260669B (OSRAM) 1993-02-26 1994-02-18

Country Status (20)

Country Link
US (1) US5670503A (OSRAM)
EP (1) EP0686156B1 (OSRAM)
JP (1) JP3569917B2 (OSRAM)
KR (1) KR100313615B1 (OSRAM)
CN (1) CN1041929C (OSRAM)
AT (1) ATE220677T1 (OSRAM)
AU (1) AU681625B2 (OSRAM)
CA (1) CA2156919A1 (OSRAM)
DE (1) DE69430988T2 (OSRAM)
DK (1) DK0686156T3 (OSRAM)
ES (1) ES2176235T3 (OSRAM)
GB (1) GB9303993D0 (OSRAM)
HU (1) HUT70832A (OSRAM)
IL (1) IL108562A (OSRAM)
MX (1) MX9401408A (OSRAM)
PT (1) PT686156E (OSRAM)
RU (1) RU2124517C1 (OSRAM)
TW (1) TW260669B (OSRAM)
WO (1) WO1994019350A1 (OSRAM)
ZA (1) ZA94787B (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7821193B2 (en) 2007-11-23 2010-10-26 Tsinghua University Color pixel element for field emission display
US7863806B2 (en) 2007-11-23 2011-01-04 Tsinghua University Color field emission display having carbon nanotubes

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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EP1360901A1 (en) 1996-04-25 2003-11-12 Nissan Chemical Industries, Limited 2,3-cyclic substituted derivatives of 3-hydroxyacrolein and 3-hydroxyacrylic acid as pesticides
US6514977B1 (en) 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
AU7726898A (en) 1997-05-22 1998-12-11 G.D. Searle & Co. Pyrazole derivatives as p38 kinase inhibitors
US6979686B1 (en) 2001-12-07 2005-12-27 Pharmacia Corporation Substituted pyrazoles as p38 kinase inhibitors
KR100704059B1 (ko) 1997-06-12 2007-04-05 롱프랑 로라 리미티드 이미다졸릴-사이클릭 아세탈
CA2294057A1 (en) 1997-06-13 1998-12-17 Smithkline Beecham Corporation Novel pyrazole and pyrazoline substituted compounds
NZ504465A (en) 1997-10-14 2001-11-30 Welfide Corp 1-Phenylacylamino substituted piperazine derivatives which are 4-substituted by a heteroaryl group
US6335340B1 (en) 1997-12-19 2002-01-01 Smithkline Beecham Corporation compounds of heteroaryl substituted imidazole, their pharmaceutical compositons and uses
US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
US6599910B1 (en) * 1998-08-20 2003-07-29 Smithkline Beecham Corporation Substituted triazole compounds
EP1126852B1 (en) 1998-11-04 2004-01-21 SmithKline Beecham Corporation Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines
AU6729900A (en) * 1999-08-31 2001-03-26 Fujisawa Pharmaceutical Co., Ltd. Organ preservatives
HUP0200207A3 (en) * 1999-11-10 2004-07-28 Ortho Mcneil Pharm Inc Substituted 2-aryl-3-(hetroaryl)-imidazo [1,2-a] pyrimidines, and related pharmaceutical compositions and methods for their preparation
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) * 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
US6759410B1 (en) 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
DE60020595T2 (de) 1999-11-23 2006-03-16 Smithkline Beecham Corp. 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p38-kinase-inhibitoren
DE60015599T2 (de) 1999-11-23 2005-11-03 Smithkline Beecham Corp. 3,4-DIHYDRO-(1H)CHINAZOLIN-2-ON-VERBINDUNGEN ALS CSBP/p38-KINASE-INHIBITOREN
ATE305787T1 (de) 1999-11-23 2005-10-15 Smithkline Beecham Corp 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren
US7235551B2 (en) 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
CZ20031125A3 (cs) 2000-10-23 2003-10-15 Smithkline Beecham Corporation Nové sloučeniny
RU2316556C2 (ru) * 2000-11-17 2008-02-10 Бристол-Маерс Сквибб Компани СПОСОБЫ ЛЕЧЕНИЯ СОСТОЯНИЙ, ОБУСЛОВЛЕННЫХ p38 КИНАЗАМИ, И ПИРРОЛОТРИАЗИНОВЫЕ СОЕДИНЕНИЯ, ПРИМЕНИМЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ
EP1345938A1 (en) * 2000-12-28 2003-09-24 Neurocrine Biosciences, Inc. Tricyclic crf receptor antagonists
ES2289116T3 (es) * 2001-05-24 2008-02-01 Eli Lilly And Company Nuevos derivados de pirrol como agentes farmaceuticos.
US6566357B1 (en) * 2001-09-20 2003-05-20 The Procter & Gamble Co. Spirocyclic-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
US7629350B2 (en) 2002-04-19 2009-12-08 Smithkline Beecham Corporation Compounds
ES2278170T3 (es) 2002-07-09 2007-08-01 BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG Composiciones farmaceuticas de anticolinergicos e inhibidores de la quinasa p38 en el tratamiento de enfermedades respiratorias.
EP1572113B1 (en) * 2002-08-26 2017-05-17 Takeda Pharmaceutical Company Limited Calcium receptor modulating compound and use thereof
US7572922B2 (en) 2003-01-27 2009-08-11 Merck & Co., Inc. Substituted pyrazoles, compositions containing such compounds and methods of use
HRP20080311T3 (hr) * 2004-06-04 2008-07-31 Merck & Co. Inc. Derivati pirazola, pripravci koji sadrže takve spojeve i postupci za njihovu primjenu
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1 (es) 2004-12-24 2006-10-06 Boehringer Ingelheim Int Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
AR053346A1 (es) 2005-03-25 2007-05-02 Glaxo Group Ltd Compuesto derivado de 8h -pirido (2,3-d) pirimidin -7 ona 2,4,8- trisustituida composicion farmaceutica y uso para preparar una composicion para tratamiento y profilxis de una enfermedad mediada por la quinasa csbp/ rk/p38
US7423042B2 (en) 2005-03-25 2008-09-09 Glaxo Group Limited Compounds
MX2007012951A (es) 2005-03-25 2008-01-11 Glaxo Group Ltd Procedimiento para preparar derivados de pirido[2,3-d] pirimidin-7-ona y 3,4-dihidropirimidino[4,5-d]pirimidin-2(1h)-ona.
UY29439A1 (es) 2005-03-25 2006-10-02 Glaxo Group Ltd Nuevos compuestos
WO2007015999A2 (en) * 2005-07-26 2007-02-08 Merck & Co., Inc. Process for synthesizing a substituted pyrazole
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
US20110195962A1 (en) * 2007-08-16 2011-08-11 Alcon Research, Ltd. Use of multi-pharmacophore compounds to treat nasal disorders
EP2203453A1 (en) * 2007-09-20 2010-07-07 Wyeth a Corporation of the State of Delaware Pyrazolo[5, 1-c] [1,2,4]triazines, methods for preparation and use thereof
EP2402344A1 (en) * 2010-06-29 2012-01-04 Basf Se Pyrazole fused bicyclic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06502178A (ja) * 1990-12-31 1994-03-10 藤沢薬品工業株式会社 イミダゾトリアジン誘導体
US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7821193B2 (en) 2007-11-23 2010-10-26 Tsinghua University Color pixel element for field emission display
US7863806B2 (en) 2007-11-23 2011-01-04 Tsinghua University Color field emission display having carbon nanotubes

Also Published As

Publication number Publication date
JPH08507056A (ja) 1996-07-30
CN1120840A (zh) 1996-04-17
EP0686156A1 (en) 1995-12-13
RU2124517C1 (ru) 1999-01-10
GB9303993D0 (en) 1993-04-14
HU9402459D0 (en) 1994-11-28
ZA94787B (en) 1994-09-08
KR100313615B1 (ko) 2002-05-30
ES2176235T3 (es) 2002-12-01
DE69430988D1 (de) 2002-08-22
CN1041929C (zh) 1999-02-03
DK0686156T3 (da) 2002-11-11
IL108562A (en) 1997-06-10
AU6010894A (en) 1994-09-14
JP3569917B2 (ja) 2004-09-29
AU681625B2 (en) 1997-09-04
HUT70832A (en) 1995-11-28
PT686156E (pt) 2002-12-31
IL108562A0 (en) 1994-05-30
DE69430988T2 (de) 2002-11-28
EP0686156B1 (en) 2002-07-17
MX9401408A (es) 1994-08-31
WO1994019350A1 (en) 1994-09-01
CA2156919A1 (en) 1994-09-01
ATE220677T1 (de) 2002-08-15
KR960701055A (ko) 1996-02-24
US5670503A (en) 1997-09-23

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