TW222621B - - Google Patents

Info

Publication number
TW222621B
TW222621B TW081110206A TW81110206A TW222621B TW 222621 B TW222621 B TW 222621B TW 081110206 A TW081110206 A TW 081110206A TW 81110206 A TW81110206 A TW 81110206A TW 222621 B TW222621 B TW 222621B
Authority
TW
Taiwan
Prior art keywords
same
hyperparathyroidism
antirheumatic
remedy
promising
Prior art date
Application number
TW081110206A
Other languages
English (en)
Chinese (zh)
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of TW222621B publication Critical patent/TW222621B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
TW081110206A 1991-12-18 1992-12-18 TW222621B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP36105191 1991-12-18

Publications (1)

Publication Number Publication Date
TW222621B true TW222621B (enExample) 1994-04-21

Family

ID=18471985

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081110206A TW222621B (enExample) 1991-12-18 1992-12-18

Country Status (13)

Country Link
US (1) US5436401A (enExample)
EP (1) EP0619304B1 (enExample)
JP (1) JP3493037B2 (enExample)
KR (1) KR100247214B1 (enExample)
AT (1) ATE157966T1 (enExample)
DE (1) DE69222183T2 (enExample)
DK (1) DK0619304T3 (enExample)
ES (1) ES2107650T3 (enExample)
GR (1) GR3025468T3 (enExample)
HK (1) HK1002729A1 (enExample)
SG (1) SG78265A1 (enExample)
TW (1) TW222621B (enExample)
WO (1) WO1993012083A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3563310D1 (en) * 1985-07-30 1988-07-21 Salzgitter Ind Method and device for the preparation of suspensions with constant indications from basic materials with variable properties
US6103709A (en) * 1993-12-23 2000-08-15 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases
US6121469A (en) 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
EP0764443B1 (en) * 1994-04-19 2002-08-14 Chugai Seiyaku Kabushiki Kaisha Products for the treatment of cachexia associated with tumors
GB9607034D0 (en) * 1996-04-03 1996-06-05 Leo Pharm Prod Ltd Chemical compounds
AU4244997A (en) * 1996-09-03 1998-03-26 Chugai Seiyaku Kabushiki Kaisha Intermediates for the synthesis of vitamin d and steroid derivatives and processes for preparation thereof
GB9804861D0 (en) * 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
CN1150973C (zh) 1998-07-03 2004-05-26 中外制药株式会社 光化学反应用紫外线照射装置以及使用它的维生素d衍生物的制备方法
DK1219599T3 (da) * 1999-08-27 2010-05-25 Hiroaki Takayama Vitamin-D-derivater som har substituenter i 2-alfa-position
EP1275643A4 (en) 2000-04-19 2009-06-03 Chugai Pharmaceutical Co Ltd DERIVATIVES OF VITAMIN D
DK1295871T3 (da) 2000-06-15 2011-07-11 Chugai Pharmaceutical Co Ltd Vitamin D-derivater med et 22-oxa- eller 22-thiaatom, en C17-sidekæde substitueret med en syre-, ester- eller amid-gruppe og en 16(17)-dobbeltbinding
WO2002017932A1 (fr) * 2000-08-30 2002-03-07 Chugai Seiyaku Kabushiki Kaisha Preparations d'oct
WO2012122451A2 (en) 2011-03-09 2012-09-13 Teva Pharmaceutical Industries Ltd. Polymorphs of maxacalcitol and process for the preparation of maxacalcitol
CN102796134B (zh) * 2012-08-31 2015-07-01 甘肃皓天化学科技有限公司 一种马沙骨化醇中间体的制备方法
CN103508999B (zh) 2013-10-12 2015-05-13 浙江海正药业股份有限公司 马沙骨化醇的合成中间体及其制备方法和用途
CN107286067A (zh) * 2016-04-05 2017-10-24 湖南华腾制药有限公司 一种马沙骨化醇的制备方法
CN114728874B (zh) 2019-11-27 2024-04-26 研成精密化学株式会社 用于制备马沙骨化醇的方法及用于其的中间体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61140560A (ja) * 1984-12-12 1986-06-27 Chugai Pharmaceut Co Ltd ２０−オキサ−２１−ノルビタミンｄ３誘導体
JPS61267550A (ja) * 1984-12-28 1986-11-27 Chugai Pharmaceut Co Ltd ９，１０−セコ−５，７，１０（１９）−プレグナトリエン誘導体
JP3050564B2 (ja) * 1989-12-15 2000-06-12 中外製薬株式会社 新規な２２―オキサビタミンｄ誘導体

Also Published As

Publication number Publication date
SG78265A1 (en) 2001-02-20
DE69222183T2 (de) 1998-01-22
DK0619304T3 (da) 1998-02-16
EP0619304B1 (en) 1997-09-10
EP0619304A4 (en) 1995-03-29
WO1993012083A1 (fr) 1993-06-24
EP0619304A1 (en) 1994-10-12
HK1002729A1 (en) 1998-09-11
US5436401A (en) 1995-07-25
KR940703807A (ko) 1994-12-12
ES2107650T3 (es) 1997-12-01
ATE157966T1 (de) 1997-09-15
GR3025468T3 (en) 1998-02-27
DE69222183D1 (de) 1997-10-16
JPH0672994A (ja) 1994-03-15
KR100247214B1 (ko) 2000-03-15
JP3493037B2 (ja) 2004-02-03

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