GR3025468T3 - 22-oxacholecalciferol derivative and production thereof. - Google Patents

22-oxacholecalciferol derivative and production thereof.

Info

Publication number
GR3025468T3
GR3025468T3 GR970403118T GR970403118T GR3025468T3 GR 3025468 T3 GR3025468 T3 GR 3025468T3 GR 970403118 T GR970403118 T GR 970403118T GR 970403118 T GR970403118 T GR 970403118T GR 3025468 T3 GR3025468 T3 GR 3025468T3
Authority
GR
Greece
Prior art keywords
production
oxacholecalciferol
same
oxacholecalciferol derivative
derivative
Prior art date
Application number
GR970403118T
Other languages
English (en)
Inventor
Masahiro Kato
Tetsuhiro Mikami
Kiyoshige Ochi
Hiroyoshi Watanabe
Noboru Kubodera
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of GR3025468T3 publication Critical patent/GR3025468T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
GR970403118T 1991-12-18 1997-11-25 22-oxacholecalciferol derivative and production thereof. GR3025468T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP36105191 1991-12-18
PCT/JP1992/001662 WO1993012083A1 (en) 1991-12-18 1992-12-18 22-oxacholecalciferol derivative and production thereof

Publications (1)

Publication Number Publication Date
GR3025468T3 true GR3025468T3 (en) 1998-02-27

Family

ID=18471985

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970403118T GR3025468T3 (en) 1991-12-18 1997-11-25 22-oxacholecalciferol derivative and production thereof.

Country Status (13)

Country Link
US (1) US5436401A (el)
EP (1) EP0619304B1 (el)
JP (1) JP3493037B2 (el)
KR (1) KR100247214B1 (el)
AT (1) ATE157966T1 (el)
DE (1) DE69222183T2 (el)
DK (1) DK0619304T3 (el)
ES (1) ES2107650T3 (el)
GR (1) GR3025468T3 (el)
HK (1) HK1002729A1 (el)
SG (1) SG78265A1 (el)
TW (1) TW222621B (el)
WO (1) WO1993012083A1 (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3563310D1 (en) * 1985-07-30 1988-07-21 Salzgitter Ind Method and device for the preparation of suspensions with constant indications from basic materials with variable properties
US6121469A (en) 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
US6103709A (en) * 1993-12-23 2000-08-15 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases
US5977092A (en) * 1994-04-19 1999-11-02 Chugai Seiyaku Kabushiki Kaisha Drug for curing/ameliorating concomitant syndrome of tumor
GB9607034D0 (en) * 1996-04-03 1996-06-05 Leo Pharm Prod Ltd Chemical compounds
EP1426352A2 (en) * 1996-09-03 2004-06-09 The Trustees of Columbia University in the City of New York Intermediates for the sythesis of vitamin D and steroid derivatives
GB9804861D0 (en) * 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
IL140560A0 (en) * 1998-07-03 2002-02-10 Chugai Pharmaceutical Co Ltd Ultraviolet irradiation apparatus for photochemical reaction and preparation process of vitamin d derivatiive making use of the same
WO2001016099A1 (fr) * 1999-08-27 2001-03-08 Chugai Seiyaku Kabushiki Kaisha DÉRIVÉS DE VITAMINE D AYANT DES SUBSTITUANTS À LA POSITION 2$g(a)
EP1275643A4 (en) 2000-04-19 2009-06-03 Chugai Pharmaceutical Co Ltd DERIVATIVES OF VITAMIN D
KR100786053B1 (ko) * 2000-06-15 2007-12-17 쥬가이 세이야쿠 가부시키가이샤 비타민 ｄ 유도체
KR100611544B1 (ko) * 2000-08-30 2006-08-10 쥬가이 세이야쿠 가부시키가이샤 오씨티 제제
JP2014514274A (ja) 2011-03-09 2014-06-19 テバ ファーマシューティカル インダストリーズ リミティド マキサカルシトールの多形およびマキサカルシトールの調製方法
CN102796134B (zh) * 2012-08-31 2015-07-01 甘肃皓天化学科技有限公司 一种马沙骨化醇中间体的制备方法
CN103508999B (zh) 2013-10-12 2015-05-13 浙江海正药业股份有限公司 马沙骨化醇的合成中间体及其制备方法和用途
CN107286067A (zh) * 2016-04-05 2017-10-24 湖南华腾制药有限公司 一种马沙骨化醇的制备方法
US20230065886A1 (en) 2019-11-27 2023-03-02 Yonsung Fine Chemical Co., Ltd. Method for producing maxacalcitol, and intermediate therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61140560A (ja) * 1984-12-12 1986-06-27 Chugai Pharmaceut Co Ltd ２０−オキサ−２１−ノルビタミンｄ３誘導体
JPS61267550A (ja) * 1984-12-28 1986-11-27 Chugai Pharmaceut Co Ltd ９，１０−セコ−５，７，１０（１９）−プレグナトリエン誘導体
JP3050564B2 (ja) * 1989-12-15 2000-06-12 中外製薬株式会社 新規な２２―オキサビタミンｄ誘導体

Also Published As

Publication number Publication date
KR100247214B1 (ko) 2000-03-15
EP0619304A4 (en) 1995-03-29
HK1002729A1 (en) 1998-09-11
JP3493037B2 (ja) 2004-02-03
EP0619304B1 (en) 1997-09-10
DE69222183T2 (de) 1998-01-22
EP0619304A1 (en) 1994-10-12
WO1993012083A1 (en) 1993-06-24
KR940703807A (ko) 1994-12-12
US5436401A (en) 1995-07-25
ES2107650T3 (es) 1997-12-01
DK0619304T3 (da) 1998-02-16
TW222621B (el) 1994-04-21
JPH0672994A (ja) 1994-03-15
SG78265A1 (en) 2001-02-20
ATE157966T1 (de) 1997-09-15
DE69222183D1 (de) 1997-10-16

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