TW201919616A - 用於治療t-pll的化合物 - Google Patents

用於治療t-pll的化合物 Download PDF

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Publication number
TW201919616A
TW201919616A TW107120389A TW107120389A TW201919616A TW 201919616 A TW201919616 A TW 201919616A TW 107120389 A TW107120389 A TW 107120389A TW 107120389 A TW107120389 A TW 107120389A TW 201919616 A TW201919616 A TW 201919616A
Authority
TW
Taiwan
Prior art keywords
pll
cells
acceptable salt
pharmaceutically acceptable
edo
Prior art date
Application number
TW107120389A
Other languages
English (en)
Chinese (zh)
Inventor
湯瑪士 約爾格 梅林
馬可 赫林
Original Assignee
盧森堡商歐陸斯迪公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 盧森堡商歐陸斯迪公司 filed Critical 盧森堡商歐陸斯迪公司
Publication of TW201919616A publication Critical patent/TW201919616A/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW107120389A 2017-06-13 2018-06-13 用於治療t-pll的化合物 TW201919616A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
??1709402.0 2017-06-13
GBGB1709402.0A GB201709402D0 (en) 2017-06-13 2017-06-13 Compounds for treating t-pll

Publications (1)

Publication Number Publication Date
TW201919616A true TW201919616A (zh) 2019-06-01

Family

ID=59358363

Family Applications (1)

Application Number Title Priority Date Filing Date
TW107120389A TW201919616A (zh) 2017-06-13 2018-06-13 用於治療t-pll的化合物

Country Status (14)

Country Link
US (4) US11318117B2 (enExample)
EP (1) EP3638231B1 (enExample)
JP (1) JP7195283B2 (enExample)
KR (1) KR102655833B1 (enExample)
AR (1) AR112101A1 (enExample)
AU (1) AU2018285821B2 (enExample)
BR (1) BR112019026484A2 (enExample)
CA (1) CA3067276A1 (enExample)
ES (1) ES2966954T3 (enExample)
GB (1) GB201709402D0 (enExample)
IL (1) IL271017A (enExample)
MX (1) MX392103B (enExample)
TW (1) TW201919616A (enExample)
WO (1) WO2018229132A1 (enExample)

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GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
EP3897626B1 (en) * 2018-12-18 2025-09-10 Mundipharma International Corporation Limited Tinostamustine for treating multiple myeloma
CA3149796A1 (en) * 2019-08-02 2021-02-11 Onehealthcompany, Inc. Anti-cancer agents for the treatment of canine cancers

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Also Published As

Publication number Publication date
CA3067276A1 (en) 2018-12-20
JP2020523359A (ja) 2020-08-06
KR20200015563A (ko) 2020-02-12
EP3638231C0 (en) 2023-12-20
US20220401417A1 (en) 2022-12-22
MX2019015208A (es) 2022-05-03
AU2018285821B2 (en) 2024-07-04
AR112101A1 (es) 2019-09-18
EP3638231A1 (en) 2020-04-22
ES2966954T3 (es) 2024-04-25
US12370178B2 (en) 2025-07-29
MX392103B (es) 2025-03-21
US20260083707A1 (en) 2026-03-26
US20200113871A1 (en) 2020-04-16
US20240316009A1 (en) 2024-09-26
AU2018285821A1 (en) 2019-12-19
US11318117B2 (en) 2022-05-03
US11918558B2 (en) 2024-03-05
GB201709402D0 (en) 2017-07-26
IL271017A (en) 2020-01-30
JP7195283B2 (ja) 2022-12-23
KR102655833B1 (ko) 2024-04-08
EP3638231B1 (en) 2023-12-20
BR112019026484A2 (pt) 2020-07-14
WO2018229132A1 (en) 2018-12-20

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