AR112101A1 - Tinostamustina para usar en el tratamiento de la leucemia prolinfocítica de celulas t (t-pll). - Google Patents
Tinostamustina para usar en el tratamiento de la leucemia prolinfocítica de celulas t (t-pll).Info
- Publication number
- AR112101A1 AR112101A1 ARP180101622A ARP180101622A AR112101A1 AR 112101 A1 AR112101 A1 AR 112101A1 AR P180101622 A ARP180101622 A AR P180101622A AR P180101622 A ARP180101622 A AR P180101622A AR 112101 A1 AR112101 A1 AR 112101A1
- Authority
- AR
- Argentina
- Prior art keywords
- tinostamustine
- pll
- leukemia
- cell
- prolinphocytic
- Prior art date
Links
- GISXTRIGVCKQBX-UHFFFAOYSA-N 7-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]-n-hydroxyheptanamide Chemical compound ClCCN(CCCl)C1=CC=C2N(C)C(CCCCCCC(=O)NO)=NC2=C1 GISXTRIGVCKQBX-UHFFFAOYSA-N 0.000 title abstract 2
- 229940070131 tinostamustine Drugs 0.000 title abstract 2
- 208000032839 leukemia Diseases 0.000 title 1
- 208000033759 Prolymphocytic T-Cell Leukemia Diseases 0.000 abstract 2
- 208000026651 T-cell prolymphocytic leukemia Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1709402.0A GB201709402D0 (en) | 2017-06-13 | 2017-06-13 | Compounds for treating t-pll |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR112101A1 true AR112101A1 (es) | 2019-09-18 |
Family
ID=59358363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180101622A AR112101A1 (es) | 2017-06-13 | 2018-06-13 | Tinostamustina para usar en el tratamiento de la leucemia prolinfocítica de celulas t (t-pll). |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11318117B2 (enExample) |
| EP (1) | EP3638231B1 (enExample) |
| JP (1) | JP7195283B2 (enExample) |
| KR (1) | KR102655833B1 (enExample) |
| AR (1) | AR112101A1 (enExample) |
| AU (1) | AU2018285821B2 (enExample) |
| BR (1) | BR112019026484A2 (enExample) |
| CA (1) | CA3067276A1 (enExample) |
| ES (1) | ES2966954T3 (enExample) |
| GB (1) | GB201709402D0 (enExample) |
| IL (1) | IL271017A (enExample) |
| MX (1) | MX392103B (enExample) |
| TW (1) | TW201919616A (enExample) |
| WO (1) | WO2018229132A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201409471D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB201409485D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US11266631B2 (en) | 2016-10-11 | 2022-03-08 | Purdue Pharmaceutical Products L.P. | Hodgkin lymphoma therapy |
| GB201709406D0 (en) | 2017-06-13 | 2017-07-26 | Euro-Cletique S A | Compounds for treating TNBC |
| GB201709405D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating ovarian cancer |
| GB201709402D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating t-pll |
| GB201709403D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating sarcoma |
| WO2020128912A1 (en) * | 2018-12-18 | 2020-06-25 | Mundipharma International Corporation Limited | Compounds for treating lymphoma or a t-cell malignant disease |
| EP4007585A4 (en) * | 2019-08-02 | 2023-11-08 | OneHealthCompany, Inc. | TREATMENT OF CANINE CANCERS |
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| DE34727C (de) | Ch. H. TH. HAVEMANN in Paris, 16 rue Bleue | Verfahren zur direkten Gewinnung metallischen Bleis | ||
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| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| US5369108A (en) | 1991-10-04 | 1994-11-29 | Sloan-Kettering Institute For Cancer Research | Potent inducers of terminal differentiation and methods of use thereof |
| GB9126209D0 (en) | 1991-12-10 | 1992-02-12 | Orion Yhtymae Oy | Drug formulations for parenteral use |
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| DE69819721T2 (de) | 1997-06-13 | 2004-09-23 | Cydex Inc., Overland Park | Zusammensetzung mit erhöhter lagerstabilität enthaltend cyclodextrin und wirkstoffe oder wirkstoff-vorstufen, die in wasserunlösliche komponenten zersetzt werden |
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| PE20020354A1 (es) | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
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| AU2002243231A1 (en) | 2000-11-21 | 2002-07-24 | Wake Forest University | Method of treating autoimmune diseases |
| CN1764648A (zh) | 2003-01-13 | 2006-04-26 | 安斯泰来制药有限公司 | 作为组蛋白脱乙酰酶(hdac)抑制剂的异羟肟酸衍生物 |
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| JP2007501775A (ja) | 2003-08-07 | 2007-02-01 | ノバルティス アクチエンゲゼルシャフト | 免疫抑制剤としてのヒストンデアセチラーゼ阻害剤 |
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| JP5773874B2 (ja) | 2008-10-08 | 2015-09-02 | セファロン、インク． | ベンダムスチンの調製方法 |
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| JO3659B1 (ar) | 2010-06-02 | 2020-08-27 | Astellas Deutschland Gmbh | أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية |
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| GB201409471D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB201409488D0 (en) * | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB201409485D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| AU2015356779A1 (en) | 2014-12-05 | 2017-07-13 | University of Modena and Reggio Emilia | Combinations of histone deacetylase inhibitors and bendamustine for use in the treatment of lymphoma |
| CN106580971B (zh) | 2015-10-20 | 2019-11-12 | 杭州梯诺医药科技有限公司 | 一种药物组合物及其制备方法 |
| US11266631B2 (en) | 2016-10-11 | 2022-03-08 | Purdue Pharmaceutical Products L.P. | Hodgkin lymphoma therapy |
| US20180098969A1 (en) | 2016-10-11 | 2018-04-12 | Purdue Pharmaceutical Products L.P. | Hodgkin lymphoma therapy |
| GB201709405D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating ovarian cancer |
| GB201709403D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating sarcoma |
| GB201709406D0 (en) | 2017-06-13 | 2017-07-26 | Euro-Cletique S A | Compounds for treating TNBC |
| GB201709402D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating t-pll |
| WO2020128912A1 (en) | 2018-12-18 | 2020-06-25 | Mundipharma International Corporation Limited | Compounds for treating lymphoma or a t-cell malignant disease |
-
2017
- 2017-06-13 GB GBGB1709402.0A patent/GB201709402D0/en not_active Ceased
-
2018
- 2018-06-13 ES ES18733527T patent/ES2966954T3/es active Active
- 2018-06-13 WO PCT/EP2018/065664 patent/WO2018229132A1/en not_active Ceased
- 2018-06-13 KR KR1020197037098A patent/KR102655833B1/ko active Active
- 2018-06-13 AR ARP180101622A patent/AR112101A1/es unknown
- 2018-06-13 CA CA3067276A patent/CA3067276A1/en active Pending
- 2018-06-13 JP JP2019568675A patent/JP7195283B2/ja active Active
- 2018-06-13 TW TW107120389A patent/TW201919616A/zh unknown
- 2018-06-13 US US16/621,898 patent/US11318117B2/en active Active
- 2018-06-13 AU AU2018285821A patent/AU2018285821B2/en active Active
- 2018-06-13 BR BR112019026484-1A patent/BR112019026484A2/pt not_active Application Discontinuation
- 2018-06-13 MX MX2019015208A patent/MX392103B/es unknown
- 2018-06-13 EP EP18733527.8A patent/EP3638231B1/en active Active
-
2019
- 2019-11-28 IL IL271017A patent/IL271017A/en unknown
-
2022
- 2022-04-27 US US17/730,276 patent/US11918558B2/en active Active
-
2024
- 2024-01-25 US US18/422,118 patent/US12370178B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR102655833B1 (ko) | 2024-04-08 |
| TW201919616A (zh) | 2019-06-01 |
| AU2018285821A1 (en) | 2019-12-19 |
| WO2018229132A1 (en) | 2018-12-20 |
| KR20200015563A (ko) | 2020-02-12 |
| US12370178B2 (en) | 2025-07-29 |
| US20220401417A1 (en) | 2022-12-22 |
| JP2020523359A (ja) | 2020-08-06 |
| EP3638231B1 (en) | 2023-12-20 |
| MX2019015208A (es) | 2022-05-03 |
| BR112019026484A2 (pt) | 2020-07-14 |
| JP7195283B2 (ja) | 2022-12-23 |
| ES2966954T3 (es) | 2024-04-25 |
| MX392103B (es) | 2025-03-21 |
| IL271017A (en) | 2020-01-30 |
| US20240316009A1 (en) | 2024-09-26 |
| GB201709402D0 (en) | 2017-07-26 |
| EP3638231A1 (en) | 2020-04-22 |
| AU2018285821B2 (en) | 2024-07-04 |
| US11318117B2 (en) | 2022-05-03 |
| US11918558B2 (en) | 2024-03-05 |
| US20200113871A1 (en) | 2020-04-16 |
| EP3638231C0 (en) | 2023-12-20 |
| CA3067276A1 (en) | 2018-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |