MX2018010191A - Inhibidores de glucosidasa. - Google Patents

Inhibidores de glucosidasa.

Info

Publication number
MX2018010191A
MX2018010191A MX2018010191A MX2018010191A MX2018010191A MX 2018010191 A MX2018010191 A MX 2018010191A MX 2018010191 A MX2018010191 A MX 2018010191A MX 2018010191 A MX2018010191 A MX 2018010191A MX 2018010191 A MX2018010191 A MX 2018010191A
Authority
MX
Mexico
Prior art keywords
glycosidase inhibitors
glycosidase
inhibitors
tauopathies
alzheimer
Prior art date
Application number
MX2018010191A
Other languages
English (en)
Inventor
S Kulkarni Santosh
Gajendra Giri Awadut
Quattropani Anna
Original Assignee
Asceneuron S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asceneuron S A filed Critical Asceneuron S A
Publication of MX2018010191A publication Critical patent/MX2018010191A/es

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
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    • C07B2200/09—Geometrical isomers

Abstract

Los compuestos de fórmula (I) en donde A, R, W, Q, n y m tienen el significado de acuerdo con la reivindicaciones y se pueden utilizar, entre otros, para el tratamiento de tautopatías y enfermedad de Alzheimer.
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IL268501A (en) 2019-09-26
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US20190388415A1 (en) 2019-12-26
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