TW201821078A - 治療癌症之方法 - Google Patents

治療癌症之方法 Download PDF

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Publication number
TW201821078A
TW201821078A TW106141957A TW106141957A TW201821078A TW 201821078 A TW201821078 A TW 201821078A TW 106141957 A TW106141957 A TW 106141957A TW 106141957 A TW106141957 A TW 106141957A TW 201821078 A TW201821078 A TW 201821078A
Authority
TW
Taiwan
Prior art keywords
ret
subject
cancer
fusion
genetic change
Prior art date
Application number
TW106141957A
Other languages
English (en)
Chinese (zh)
Inventor
強納森 伊廉 林
博剔 S 摩他尼
理查 蘭丁
魯波 A 巴托
珍妮佛 萊特 奧利佛
Original Assignee
美商醫科泰生技
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美商醫科泰生技 filed Critical 美商醫科泰生技
Publication of TW201821078A publication Critical patent/TW201821078A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW106141957A 2016-12-01 2017-11-30 治療癌症之方法 TW201821078A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662428947P 2016-12-01 2016-12-01
US62/428,947 2016-12-01

Publications (1)

Publication Number Publication Date
TW201821078A true TW201821078A (zh) 2018-06-16

Family

ID=62241840

Family Applications (1)

Application Number Title Priority Date Filing Date
TW106141957A TW201821078A (zh) 2016-12-01 2017-11-30 治療癌症之方法

Country Status (6)

Country Link
US (1) US10799503B2 (enExample)
EP (1) EP3548007A4 (enExample)
JP (1) JP7105774B2 (enExample)
CN (1) CN110191705A (enExample)
TW (1) TW201821078A (enExample)
WO (1) WO2018102455A1 (enExample)

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EP3740491A1 (en) 2018-01-18 2020-11-25 Array Biopharma, Inc. Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors
EP3740486A1 (en) 2018-01-18 2020-11-25 Array Biopharma, Inc. Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors
SG11202009681YA (en) 2018-04-03 2020-10-29 Blueprint Medicines Corp Ret inhibitor for use in treating cancer having a ret alteration
WO2021243192A1 (en) 2020-05-29 2021-12-02 Blueprint Medicines Corporation Solid forms of pralsetinib
CR20220666A (es) 2020-05-29 2023-05-05 Blueprint Medicines Corp Composiciones farmacéuticas de pralsetinib
CN112933095A (zh) * 2020-12-29 2021-06-11 上海岸阔医药科技有限公司 预防或治疗egfr功能异常相关的副作用的方法

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Also Published As

Publication number Publication date
EP3548007A4 (en) 2020-08-12
EP3548007A1 (en) 2019-10-09
CN110191705A (zh) 2019-08-30
JP7105774B2 (ja) 2022-07-25
US10799503B2 (en) 2020-10-13
US20200069688A1 (en) 2020-03-05
WO2018102455A1 (en) 2018-06-07
JP2019536790A (ja) 2019-12-19

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