JP7105774B2 - がん治療のための方法 - Google Patents

がん治療のための方法 Download PDF

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JP7105774B2
JP7105774B2 JP2019529182A JP2019529182A JP7105774B2 JP 7105774 B2 JP7105774 B2 JP 7105774B2 JP 2019529182 A JP2019529182 A JP 2019529182A JP 2019529182 A JP2019529182 A JP 2019529182A JP 7105774 B2 JP7105774 B2 JP 7105774B2
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ret
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cancer
fusion
genetic alteration
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JP2019536790A5 (enExample
JP2019536790A (ja
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ジョナサン エー－レン リム
プラティック エス． ムルタニ
リチャード ランディン
ルパル エー． パテル
ジェニファー ライト オリバー
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イグナイタ インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2019529182A 2016-12-01 2017-11-29 がん治療のための方法 Expired - Fee Related JP7105774B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662428947P 2016-12-01 2016-12-01
US62/428,947 2016-12-01
PCT/US2017/063779 WO2018102455A1 (en) 2016-12-01 2017-11-29 Methods for the treatment of cancer

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JP2019536790A JP2019536790A (ja) 2019-12-19
JP2019536790A5 JP2019536790A5 (enExample) 2021-01-07
JP7105774B2 true JP7105774B2 (ja) 2022-07-25

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JP2019529182A Expired - Fee Related JP7105774B2 (ja) 2016-12-01 2017-11-29 がん治療のための方法

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US (1) US10799503B2 (enExample)
EP (1) EP3548007A4 (enExample)
JP (1) JP7105774B2 (enExample)
CN (1) CN110191705A (enExample)
TW (1) TW201821078A (enExample)
WO (1) WO2018102455A1 (enExample)

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RS65069B1 (sr) 2015-11-02 2024-02-29 Blueprint Medicines Corp Inhibitori ret-a
EP3740491A1 (en) 2018-01-18 2020-11-25 Array Biopharma, Inc. Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors
EP3740486A1 (en) 2018-01-18 2020-11-25 Array Biopharma, Inc. Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors
SG11202009681YA (en) 2018-04-03 2020-10-29 Blueprint Medicines Corp Ret inhibitor for use in treating cancer having a ret alteration
WO2021243192A1 (en) 2020-05-29 2021-12-02 Blueprint Medicines Corporation Solid forms of pralsetinib
CR20220666A (es) 2020-05-29 2023-05-05 Blueprint Medicines Corp Composiciones farmacéuticas de pralsetinib
CN112933095A (zh) * 2020-12-29 2021-06-11 上海岸阔医药科技有限公司 预防或治疗egfr功能异常相关的副作用的方法

Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2014050781A1 (ja) 2012-09-25 2014-04-03 中外製薬株式会社 Ｒｅｔ阻害剤
JP2016512516A (ja) 2013-03-11 2016-04-28 イグナイタ インコーポレイテッド キナゾリン誘導体の固体形態およびｂｒａｆ阻害剤としてのその使用

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JP2016512516A (ja) 2013-03-11 2016-04-28 イグナイタ インコーポレイテッド キナゾリン誘導体の固体形態およびｂｒａｆ阻害剤としてのその使用

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Also Published As

Publication number Publication date
EP3548007A4 (en) 2020-08-12
EP3548007A1 (en) 2019-10-09
TW201821078A (zh) 2018-06-16
CN110191705A (zh) 2019-08-30
US10799503B2 (en) 2020-10-13
US20200069688A1 (en) 2020-03-05
WO2018102455A1 (en) 2018-06-07
JP2019536790A (ja) 2019-12-19

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