TW200817322A - Compounds having activity at the GlyT1 transporter - Google Patents
Compounds having activity at the GlyT1 transporter Download PDFInfo
- Publication number
- TW200817322A TW200817322A TW096121972A TW96121972A TW200817322A TW 200817322 A TW200817322 A TW 200817322A TW 096121972 A TW096121972 A TW 096121972A TW 96121972 A TW96121972 A TW 96121972A TW 200817322 A TW200817322 A TW 200817322A
- Authority
- TW
- Taiwan
- Prior art keywords
- propyl
- bis
- phenyl
- compound
- trifluoromethyl
- Prior art date
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Anesthesiology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| GBGB0612420.0A GB0612420D0 (en) | 2006-06-22 | 2006-06-22 | Compounds |
Publications (1)
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| TW200817322A true TW200817322A (en) | 2008-04-16 |
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| TW096121972A TW200817322A (en) | 2006-06-22 | 2007-06-20 | Compounds having activity at the GlyT1 transporter |
Country Status (23)
| Country | Link |
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| US (1) | US20080070973A1 (OSRAM) |
| EP (1) | EP2041082B1 (OSRAM) |
| JP (1) | JP2009541261A (OSRAM) |
| KR (1) | KR20090019847A (OSRAM) |
| CN (1) | CN101506156A (OSRAM) |
| AR (1) | AR061554A1 (OSRAM) |
| AT (1) | ATE444288T1 (OSRAM) |
| AU (1) | AU2007263058A1 (OSRAM) |
| BR (1) | BRPI0713311A2 (OSRAM) |
| CA (1) | CA2655399A1 (OSRAM) |
| CL (1) | CL2007001808A1 (OSRAM) |
| CR (1) | CR10498A (OSRAM) |
| DE (1) | DE602007002642D1 (OSRAM) |
| EA (1) | EA200970044A1 (OSRAM) |
| ES (1) | ES2333918T3 (OSRAM) |
| GB (1) | GB0612420D0 (OSRAM) |
| IL (1) | IL195633A0 (OSRAM) |
| MA (1) | MA30522B1 (OSRAM) |
| NO (1) | NO20085412L (OSRAM) |
| PE (1) | PE20080380A1 (OSRAM) |
| TW (1) | TW200817322A (OSRAM) |
| WO (1) | WO2007147831A1 (OSRAM) |
| ZA (1) | ZA200810009B (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| PE20061156A1 (es) | 2004-12-23 | 2006-12-16 | Glaxo Group Ltd | Derivados de benzamida como agentes inhibidores del transportador de glicina |
| WO2008155334A2 (en) * | 2007-06-20 | 2008-12-24 | Glaxo Group Limited | Improved process of amide formation |
| SG186885A1 (en) | 2010-06-04 | 2013-02-28 | Albany Molecular Res Inc | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
| US20120035156A1 (en) * | 2010-08-09 | 2012-02-09 | Daniela Alberati | Combination of glyt1 compound with antipsychotics |
| WO2019073052A1 (en) | 2017-10-13 | 2019-04-18 | Treeway Tw001 B.V. | EDARAVONE SALT |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2746959A (en) * | 1953-06-02 | 1956-05-22 | American Home Prod | Diphenylethylenediamine-penicillin salt |
| US3145209A (en) * | 1961-07-31 | 1964-08-18 | Olin Mathieson | Substituted aminophenyl-ethylamine derivatives |
| NZ237443A (en) * | 1990-04-10 | 1993-11-25 | Asta Medica Ag | Phenalkylethylenediamine and aminomethyltetra hydroisoquinoline derivatives, platinum (ii) and (iv) complexes, methods of preparation and pharmaceutical compositions |
| GB0130696D0 (en) * | 2001-12-21 | 2002-02-06 | Smithkline Beecham Plc | Chemical Compounds |
| FR2861070B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(pyrrolidin-2-yl)methyl]benzamide et n-[(azepan-2-yl)phenylmethyl]benzamide, leur preparation et leur application en therapeutique |
| PE20061156A1 (es) * | 2004-12-23 | 2006-12-16 | Glaxo Group Ltd | Derivados de benzamida como agentes inhibidores del transportador de glicina |
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2006
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2007
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- 2007-06-20 TW TW096121972A patent/TW200817322A/zh unknown
- 2007-06-20 EA EA200970044A patent/EA200970044A1/ru unknown
- 2007-06-20 BR BRPI0713311-1A patent/BRPI0713311A2/pt not_active IP Right Cessation
- 2007-06-20 WO PCT/EP2007/056106 patent/WO2007147831A1/en not_active Ceased
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- 2007-06-20 ES ES07786764T patent/ES2333918T3/es active Active
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2008
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- 2008-12-11 CR CR10498A patent/CR10498A/es not_active Application Discontinuation
- 2008-12-19 MA MA31488A patent/MA30522B1/fr unknown
- 2008-12-30 NO NO20085412A patent/NO20085412L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080070973A1 (en) | 2008-03-20 |
| BRPI0713311A2 (pt) | 2012-03-06 |
| GB0612420D0 (en) | 2006-08-02 |
| AU2007263058A1 (en) | 2007-12-27 |
| AR061554A1 (es) | 2008-09-03 |
| DE602007002642D1 (de) | 2009-11-12 |
| IL195633A0 (en) | 2009-09-01 |
| ES2333918T3 (es) | 2010-03-02 |
| NO20085412L (no) | 2009-01-22 |
| ZA200810009B (en) | 2009-11-25 |
| CL2007001808A1 (es) | 2008-01-18 |
| CA2655399A1 (en) | 2007-12-27 |
| EP2041082A1 (en) | 2009-04-01 |
| WO2007147831A1 (en) | 2007-12-27 |
| MA30522B1 (fr) | 2009-06-01 |
| EA200970044A1 (ru) | 2009-04-28 |
| EP2041082B1 (en) | 2009-09-30 |
| ATE444288T1 (de) | 2009-10-15 |
| JP2009541261A (ja) | 2009-11-26 |
| CR10498A (es) | 2009-03-20 |
| KR20090019847A (ko) | 2009-02-25 |
| PE20080380A1 (es) | 2008-05-31 |
| CN101506156A (zh) | 2009-08-12 |
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