MA30522B1 - Composes ayant une activite au niveau du transporteur glyt1 - Google Patents
Composes ayant une activite au niveau du transporteur glyt1Info
- Publication number
- MA30522B1 MA30522B1 MA31488A MA31488A MA30522B1 MA 30522 B1 MA30522 B1 MA 30522B1 MA 31488 A MA31488 A MA 31488A MA 31488 A MA31488 A MA 31488A MA 30522 B1 MA30522 B1 MA 30522B1
- Authority
- MA
- Morocco
- Prior art keywords
- activity
- compounds
- transporter glyt1
- benzamide
- trifluoromethyl
- Prior art date
Links
- 102100022622 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Human genes 0.000 title 1
- 101000972916 Homo sapiens Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 101710083171 Sodium- and chloride-dependent glycine transporter 1 Proteins 0.000 abstract 2
- PAMCRRDMORMCSM-UHFFFAOYSA-N n-(trifluoromethyl)benzamide Chemical compound FC(F)(F)NC(=O)C1=CC=CC=C1 PAMCRRDMORMCSM-UHFFFAOYSA-N 0.000 abstract 2
- 125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 102100023145 Sodium- and chloride-dependent glycine transporter 1 Human genes 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical group [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000003235 pyrrolidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 150000003890 succinate salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0612420.0A GB0612420D0 (en) | 2006-06-22 | 2006-06-22 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA30522B1 true MA30522B1 (fr) | 2009-06-01 |
Family
ID=36803732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA31488A MA30522B1 (fr) | 2006-06-22 | 2008-12-19 | Composes ayant une activite au niveau du transporteur glyt1 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20080070973A1 (OSRAM) |
| EP (1) | EP2041082B1 (OSRAM) |
| JP (1) | JP2009541261A (OSRAM) |
| KR (1) | KR20090019847A (OSRAM) |
| CN (1) | CN101506156A (OSRAM) |
| AR (1) | AR061554A1 (OSRAM) |
| AT (1) | ATE444288T1 (OSRAM) |
| AU (1) | AU2007263058A1 (OSRAM) |
| BR (1) | BRPI0713311A2 (OSRAM) |
| CA (1) | CA2655399A1 (OSRAM) |
| CL (1) | CL2007001808A1 (OSRAM) |
| CR (1) | CR10498A (OSRAM) |
| DE (1) | DE602007002642D1 (OSRAM) |
| EA (1) | EA200970044A1 (OSRAM) |
| ES (1) | ES2333918T3 (OSRAM) |
| GB (1) | GB0612420D0 (OSRAM) |
| IL (1) | IL195633A0 (OSRAM) |
| MA (1) | MA30522B1 (OSRAM) |
| NO (1) | NO20085412L (OSRAM) |
| PE (1) | PE20080380A1 (OSRAM) |
| TW (1) | TW200817322A (OSRAM) |
| WO (1) | WO2007147831A1 (OSRAM) |
| ZA (1) | ZA200810009B (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20061156A1 (es) | 2004-12-23 | 2006-12-16 | Glaxo Group Ltd | Derivados de benzamida como agentes inhibidores del transportador de glicina |
| WO2008155334A2 (en) * | 2007-06-20 | 2008-12-24 | Glaxo Group Limited | Improved process of amide formation |
| SG186885A1 (en) | 2010-06-04 | 2013-02-28 | Albany Molecular Res Inc | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
| US20120035156A1 (en) * | 2010-08-09 | 2012-02-09 | Daniela Alberati | Combination of glyt1 compound with antipsychotics |
| WO2019073052A1 (en) | 2017-10-13 | 2019-04-18 | Treeway Tw001 B.V. | EDARAVONE SALT |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2746959A (en) * | 1953-06-02 | 1956-05-22 | American Home Prod | Diphenylethylenediamine-penicillin salt |
| US3145209A (en) * | 1961-07-31 | 1964-08-18 | Olin Mathieson | Substituted aminophenyl-ethylamine derivatives |
| NZ237443A (en) * | 1990-04-10 | 1993-11-25 | Asta Medica Ag | Phenalkylethylenediamine and aminomethyltetra hydroisoquinoline derivatives, platinum (ii) and (iv) complexes, methods of preparation and pharmaceutical compositions |
| GB0130696D0 (en) * | 2001-12-21 | 2002-02-06 | Smithkline Beecham Plc | Chemical Compounds |
| FR2861070B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(pyrrolidin-2-yl)methyl]benzamide et n-[(azepan-2-yl)phenylmethyl]benzamide, leur preparation et leur application en therapeutique |
| PE20061156A1 (es) * | 2004-12-23 | 2006-12-16 | Glaxo Group Ltd | Derivados de benzamida como agentes inhibidores del transportador de glicina |
-
2006
- 2006-06-22 GB GBGB0612420.0A patent/GB0612420D0/en not_active Ceased
-
2007
- 2007-06-20 AU AU2007263058A patent/AU2007263058A1/en not_active Abandoned
- 2007-06-20 CN CNA2007800312340A patent/CN101506156A/zh active Pending
- 2007-06-20 CL CL2007001808A patent/CL2007001808A1/es unknown
- 2007-06-20 JP JP2009515863A patent/JP2009541261A/ja not_active Withdrawn
- 2007-06-20 TW TW096121972A patent/TW200817322A/zh unknown
- 2007-06-20 EA EA200970044A patent/EA200970044A1/ru unknown
- 2007-06-20 BR BRPI0713311-1A patent/BRPI0713311A2/pt not_active IP Right Cessation
- 2007-06-20 WO PCT/EP2007/056106 patent/WO2007147831A1/en not_active Ceased
- 2007-06-20 AT AT07786764T patent/ATE444288T1/de not_active IP Right Cessation
- 2007-06-20 ES ES07786764T patent/ES2333918T3/es active Active
- 2007-06-20 US US11/765,478 patent/US20080070973A1/en not_active Abandoned
- 2007-06-20 CA CA002655399A patent/CA2655399A1/en not_active Abandoned
- 2007-06-20 AR ARP070102723A patent/AR061554A1/es unknown
- 2007-06-20 KR KR1020087030915A patent/KR20090019847A/ko not_active Withdrawn
- 2007-06-20 PE PE2007000782A patent/PE20080380A1/es not_active Application Discontinuation
- 2007-06-20 EP EP07786764A patent/EP2041082B1/en active Active
- 2007-06-20 DE DE602007002642T patent/DE602007002642D1/de active Active
-
2008
- 2008-11-25 ZA ZA200810009A patent/ZA200810009B/xx unknown
- 2008-12-01 IL IL195633A patent/IL195633A0/en unknown
- 2008-12-11 CR CR10498A patent/CR10498A/es not_active Application Discontinuation
- 2008-12-19 MA MA31488A patent/MA30522B1/fr unknown
- 2008-12-30 NO NO20085412A patent/NO20085412L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080070973A1 (en) | 2008-03-20 |
| BRPI0713311A2 (pt) | 2012-03-06 |
| GB0612420D0 (en) | 2006-08-02 |
| AU2007263058A1 (en) | 2007-12-27 |
| AR061554A1 (es) | 2008-09-03 |
| DE602007002642D1 (de) | 2009-11-12 |
| IL195633A0 (en) | 2009-09-01 |
| ES2333918T3 (es) | 2010-03-02 |
| NO20085412L (no) | 2009-01-22 |
| ZA200810009B (en) | 2009-11-25 |
| CL2007001808A1 (es) | 2008-01-18 |
| CA2655399A1 (en) | 2007-12-27 |
| EP2041082A1 (en) | 2009-04-01 |
| WO2007147831A1 (en) | 2007-12-27 |
| EA200970044A1 (ru) | 2009-04-28 |
| TW200817322A (en) | 2008-04-16 |
| EP2041082B1 (en) | 2009-09-30 |
| ATE444288T1 (de) | 2009-10-15 |
| JP2009541261A (ja) | 2009-11-26 |
| CR10498A (es) | 2009-03-20 |
| KR20090019847A (ko) | 2009-02-25 |
| PE20080380A1 (es) | 2008-05-31 |
| CN101506156A (zh) | 2009-08-12 |
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