CL2007001808A1 - Sales succinato y napadisilato de 2-(metiloxi)-n-[2-metil-1-fenil-2-(1-pirrolidinil)propil]-4,6-bis(trifluorometil)benzamida, que tienen actividad en los transportadores de glyt1; composicion farmaceutica; y su uso en el tratamiento de enfermedades tales como psicosis, demencia, esquizofrenia, entre otras. - Google Patents
Sales succinato y napadisilato de 2-(metiloxi)-n-[2-metil-1-fenil-2-(1-pirrolidinil)propil]-4,6-bis(trifluorometil)benzamida, que tienen actividad en los transportadores de glyt1; composicion farmaceutica; y su uso en el tratamiento de enfermedades tales como psicosis, demencia, esquizofrenia, entre otras.Info
- Publication number
- CL2007001808A1 CL2007001808A1 CL2007001808A CL2007001808A CL2007001808A1 CL 2007001808 A1 CL2007001808 A1 CL 2007001808A1 CL 2007001808 A CL2007001808 A CL 2007001808A CL 2007001808 A CL2007001808 A CL 2007001808A CL 2007001808 A1 CL2007001808 A1 CL 2007001808A1
- Authority
- CL
- Chile
- Prior art keywords
- psychosis
- schizophrenia
- dementia
- diseases
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Compuestos derivados de benzamida, mediadores de glyt1; composición farmacéutica; y uso en el tratamiento de enfermedades tales como psicosis, demencia, esquizofrenia, entre otras.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0612420.0A GB0612420D0 (en) | 2006-06-22 | 2006-06-22 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2007001808A1 true CL2007001808A1 (es) | 2008-01-18 |
Family
ID=36803732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2007001808A CL2007001808A1 (es) | 2006-06-22 | 2007-06-20 | Sales succinato y napadisilato de 2-(metiloxi)-n-[2-metil-1-fenil-2-(1-pirrolidinil)propil]-4,6-bis(trifluorometil)benzamida, que tienen actividad en los transportadores de glyt1; composicion farmaceutica; y su uso en el tratamiento de enfermedades tales como psicosis, demencia, esquizofrenia, entre otras. |
Country Status (23)
Country | Link |
---|---|
US (1) | US20080070973A1 (es) |
EP (1) | EP2041082B1 (es) |
JP (1) | JP2009541261A (es) |
KR (1) | KR20090019847A (es) |
CN (1) | CN101506156A (es) |
AR (1) | AR061554A1 (es) |
AT (1) | ATE444288T1 (es) |
AU (1) | AU2007263058A1 (es) |
BR (1) | BRPI0713311A2 (es) |
CA (1) | CA2655399A1 (es) |
CL (1) | CL2007001808A1 (es) |
CR (1) | CR10498A (es) |
DE (1) | DE602007002642D1 (es) |
EA (1) | EA200970044A1 (es) |
ES (1) | ES2333918T3 (es) |
GB (1) | GB0612420D0 (es) |
IL (1) | IL195633A0 (es) |
MA (1) | MA30522B1 (es) |
NO (1) | NO20085412L (es) |
PE (1) | PE20080380A1 (es) |
TW (1) | TW200817322A (es) |
WO (1) | WO2007147831A1 (es) |
ZA (1) | ZA200810009B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20061156A1 (es) | 2004-12-23 | 2006-12-16 | Glaxo Group Ltd | Derivados de benzamida como agentes inhibidores del transportador de glicina |
JP2010530397A (ja) * | 2007-06-20 | 2010-09-09 | グラクソ グループ リミテッド | アミド形成の改善方法 |
NZ604035A (en) | 2010-06-04 | 2015-02-27 | Albany Molecular Res Inc | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
US20120035156A1 (en) * | 2010-08-09 | 2012-02-09 | Daniela Alberati | Combination of glyt1 compound with antipsychotics |
CN111465597B (zh) * | 2017-10-13 | 2023-08-25 | 萃微Tw001公司 | 依达拉奉盐 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2746959A (en) * | 1953-06-02 | 1956-05-22 | American Home Prod | Diphenylethylenediamine-penicillin salt |
US3145209A (en) * | 1961-07-31 | 1964-08-18 | Olin Mathieson | Substituted aminophenyl-ethylamine derivatives |
NZ237443A (en) * | 1990-04-10 | 1993-11-25 | Asta Medica Ag | Phenalkylethylenediamine and aminomethyltetra hydroisoquinoline derivatives, platinum (ii) and (iv) complexes, methods of preparation and pharmaceutical compositions |
GB0130696D0 (en) * | 2001-12-21 | 2002-02-06 | Smithkline Beecham Plc | Chemical Compounds |
FR2861070B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(pyrrolidin-2-yl)methyl]benzamide et n-[(azepan-2-yl)phenylmethyl]benzamide, leur preparation et leur application en therapeutique |
PE20061156A1 (es) * | 2004-12-23 | 2006-12-16 | Glaxo Group Ltd | Derivados de benzamida como agentes inhibidores del transportador de glicina |
-
2006
- 2006-06-22 GB GBGB0612420.0A patent/GB0612420D0/en not_active Ceased
-
2007
- 2007-06-20 AU AU2007263058A patent/AU2007263058A1/en not_active Abandoned
- 2007-06-20 CL CL2007001808A patent/CL2007001808A1/es unknown
- 2007-06-20 WO PCT/EP2007/056106 patent/WO2007147831A1/en active Application Filing
- 2007-06-20 EA EA200970044A patent/EA200970044A1/ru unknown
- 2007-06-20 PE PE2007000782A patent/PE20080380A1/es not_active Application Discontinuation
- 2007-06-20 BR BRPI0713311-1A patent/BRPI0713311A2/pt not_active IP Right Cessation
- 2007-06-20 ES ES07786764T patent/ES2333918T3/es active Active
- 2007-06-20 AR ARP070102723A patent/AR061554A1/es unknown
- 2007-06-20 CN CNA2007800312340A patent/CN101506156A/zh active Pending
- 2007-06-20 EP EP07786764A patent/EP2041082B1/en active Active
- 2007-06-20 AT AT07786764T patent/ATE444288T1/de not_active IP Right Cessation
- 2007-06-20 CA CA002655399A patent/CA2655399A1/en not_active Abandoned
- 2007-06-20 KR KR1020087030915A patent/KR20090019847A/ko not_active Application Discontinuation
- 2007-06-20 DE DE602007002642T patent/DE602007002642D1/de active Active
- 2007-06-20 TW TW096121972A patent/TW200817322A/zh unknown
- 2007-06-20 JP JP2009515863A patent/JP2009541261A/ja not_active Withdrawn
- 2007-06-20 US US11/765,478 patent/US20080070973A1/en not_active Abandoned
-
2008
- 2008-11-25 ZA ZA200810009A patent/ZA200810009B/xx unknown
- 2008-12-01 IL IL195633A patent/IL195633A0/en unknown
- 2008-12-11 CR CR10498A patent/CR10498A/es not_active Application Discontinuation
- 2008-12-19 MA MA31488A patent/MA30522B1/fr unknown
- 2008-12-30 NO NO20085412A patent/NO20085412L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2655399A1 (en) | 2007-12-27 |
DE602007002642D1 (de) | 2009-11-12 |
EP2041082A1 (en) | 2009-04-01 |
ES2333918T3 (es) | 2010-03-02 |
PE20080380A1 (es) | 2008-05-31 |
EP2041082B1 (en) | 2009-09-30 |
AU2007263058A1 (en) | 2007-12-27 |
WO2007147831A1 (en) | 2007-12-27 |
CN101506156A (zh) | 2009-08-12 |
BRPI0713311A2 (pt) | 2012-03-06 |
KR20090019847A (ko) | 2009-02-25 |
US20080070973A1 (en) | 2008-03-20 |
JP2009541261A (ja) | 2009-11-26 |
EA200970044A1 (ru) | 2009-04-28 |
NO20085412L (no) | 2009-01-22 |
ZA200810009B (en) | 2009-11-25 |
MA30522B1 (fr) | 2009-06-01 |
AR061554A1 (es) | 2008-09-03 |
ATE444288T1 (de) | 2009-10-15 |
GB0612420D0 (en) | 2006-08-02 |
CR10498A (es) | 2009-03-20 |
IL195633A0 (en) | 2009-09-01 |
TW200817322A (en) | 2008-04-16 |
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