TW200616994A - Novel thiophene derivatives - Google Patents

Novel thiophene derivatives

Info

Publication number
TW200616994A
TW200616994A TW094125581A TW94125581A TW200616994A TW 200616994 A TW200616994 A TW 200616994A TW 094125581 A TW094125581 A TW 094125581A TW 94125581 A TW94125581 A TW 94125581A TW 200616994 A TW200616994 A TW 200616994A
Authority
TW
Taiwan
Prior art keywords
general formula
following general
thiophene derivatives
novel thiophene
lyase
Prior art date
Application number
TW094125581A
Other languages
English (en)
Inventor
Martin Bolli
Daniel Bur
Martine Clozel
Walter Fischli
David Lehmann
Boris Mathys
Claus Mueller
Oliver Nayler
Michael Scherz
Thomas Weller
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of TW200616994A publication Critical patent/TW200616994A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
TW094125581A 2004-07-29 2005-07-28 Novel thiophene derivatives TW200616994A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2004/008501 WO2006010379A1 (en) 2004-07-29 2004-07-29 Novel thiophene derivatives as immunosuppressive agents

Publications (1)

Publication Number Publication Date
TW200616994A true TW200616994A (en) 2006-06-01

Family

ID=34958296

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094125581A TW200616994A (en) 2004-07-29 2005-07-28 Novel thiophene derivatives

Country Status (23)

Country Link
US (1) US7750040B2 (zh)
EP (1) EP1805163B1 (zh)
JP (1) JP4807884B2 (zh)
KR (1) KR20070046849A (zh)
CN (1) CN1993346B (zh)
AR (1) AR050273A1 (zh)
AT (1) ATE409697T1 (zh)
AU (1) AU2005266529A1 (zh)
BR (1) BRPI0513841A (zh)
CA (1) CA2574305A1 (zh)
DE (1) DE602005010109D1 (zh)
DK (1) DK1805163T3 (zh)
ES (1) ES2313391T3 (zh)
IL (1) IL180962A0 (zh)
MX (1) MX2007000972A (zh)
NO (1) NO20071095L (zh)
PL (1) PL1805163T3 (zh)
PT (1) PT1805163E (zh)
RU (1) RU2386626C2 (zh)
SI (1) SI1805163T1 (zh)
TW (1) TW200616994A (zh)
WO (2) WO2006010379A1 (zh)
ZA (1) ZA200700535B (zh)

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TWI408139B (zh) * 2006-09-07 2013-09-11 Actelion Pharmaceuticals Ltd 新穎噻吩衍生物
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Also Published As

Publication number Publication date
AU2005266529A1 (en) 2006-02-02
RU2007107164A (ru) 2008-09-10
DE602005010109D1 (de) 2008-11-13
BRPI0513841A (pt) 2008-05-20
US20080064740A1 (en) 2008-03-13
RU2386626C2 (ru) 2010-04-20
AR050273A1 (es) 2006-10-11
SI1805163T1 (sl) 2009-02-28
PL1805163T3 (pl) 2009-04-30
WO2006010544A2 (en) 2006-02-02
ES2313391T3 (es) 2009-03-01
ATE409697T1 (de) 2008-10-15
CN1993346A (zh) 2007-07-04
CA2574305A1 (en) 2006-02-02
WO2006010379A1 (en) 2006-02-02
DK1805163T3 (da) 2008-12-15
EP1805163B1 (en) 2008-10-01
PT1805163E (pt) 2008-12-05
US7750040B2 (en) 2010-07-06
WO2006010544A3 (en) 2006-03-30
JP2008508210A (ja) 2008-03-21
CN1993346B (zh) 2011-04-27
EP1805163A2 (en) 2007-07-11
MX2007000972A (es) 2007-04-10
KR20070046849A (ko) 2007-05-03
NO20071095L (no) 2007-02-27
IL180962A0 (en) 2007-07-04
ZA200700535B (en) 2008-10-29
JP4807884B2 (ja) 2011-11-02

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