TR201809739T4 - Toll benzeri reseptör 9 antagonistleri olarak (+)-morfinanlar ve bunların terapötik amaçlı kullanımları. - Google Patents

Toll benzeri reseptör 9 antagonistleri olarak (+)-morfinanlar ve bunların terapötik amaçlı kullanımları. Download PDF

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Publication number
TR201809739T4
TR201809739T4 TR2018/09739T TR201809739T TR201809739T4 TR 201809739 T4 TR201809739 T4 TR 201809739T4 TR 2018/09739 T TR2018/09739 T TR 2018/09739T TR 201809739 T TR201809739 T TR 201809739T TR 201809739 T4 TR201809739 T4 TR 201809739T4
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tlr9
cancer
pain
disease
compound
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TR2018/09739T
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English (en)
Turkish (tr)
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N Trawick Bobby
W Berberich David
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Mallinckrodt Llc
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    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
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    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
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TR2018/09739T 2009-07-16 2010-07-16 Toll benzeri reseptör 9 antagonistleri olarak (+)-morfinanlar ve bunların terapötik amaçlı kullanımları. TR201809739T4 (tr)

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US22601509P 2009-07-16 2009-07-16
US28687709P 2009-12-16 2009-12-16

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TR201809739T4 true TR201809739T4 (tr) 2018-07-23

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US (1) US20110015219A1 (OSRAM)
EP (1) EP2453895B1 (OSRAM)
JP (1) JP5864417B2 (OSRAM)
AU (1) AU2010273253B2 (OSRAM)
CA (1) CA2768236C (OSRAM)
DK (1) DK2453895T3 (OSRAM)
ES (1) ES2674018T3 (OSRAM)
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NZ611651A (en) 2007-12-17 2014-11-28 Mallinckrodt Llc Sinomenine derivatives and processes for their synthesis
CA2709858C (en) * 2007-12-17 2016-03-29 Peter X. Wang Process and compounds for the production of (+)opiates
US8829020B2 (en) 2009-07-16 2014-09-09 Mallinckrodt Llc Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
US10363251B2 (en) 2009-07-16 2019-07-30 Mallinckrodt Llc (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
EP2593095B1 (en) * 2010-07-16 2019-03-27 Mallinckrodt LLC (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
GB201014026D0 (en) * 2010-08-20 2010-10-06 Ucl Business Plc Treatment
MX2013008749A (es) * 2011-01-31 2013-10-17 Toray Industries Agente terapeutico o profilactico para caquexia.
JP5769889B2 (ja) 2011-10-26 2015-08-26 ケムファーム・インコーポレーテッド ヒドロモルホンの安息香酸、安息香酸誘導体及びヘテロアリールカルボン酸結合体、そのプロドラッグ、製造法及び使用
CN102617470A (zh) * 2012-03-07 2012-08-01 江苏大学 青藤碱4-羟基醚化和酯化衍生物、制备方法及用途
CN103387579A (zh) * 2012-05-08 2013-11-13 长沙理工大学 4-苄氧基-17-苯磺酰吗啡喃-6-酮的合成
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