TR200400701T4 - lgG üretme yöntemi - Google Patents

lgG üretme yöntemi

Info

Publication number
TR200400701T4
TR200400701T4 TR2004/00701T TR200400701T TR200400701T4 TR 200400701 T4 TR200400701 T4 TR 200400701T4 TR 2004/00701 T TR2004/00701 T TR 2004/00701T TR 200400701 T TR200400701 T TR 200400701T TR 200400701 T4 TR200400701 T4 TR 200400701T4
Authority
TR
Turkey
Prior art keywords
igg
igg fraction
iii
fraction
derived
Prior art date
Application number
TR2004/00701T
Other languages
English (en)
Inventor
Anderson Inger
Lindquist Lars-Olof
Original Assignee
Amersham Biosciences Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20279068&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200400701(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham Biosciences Ab filed Critical Amersham Biosciences Ab
Publication of TR200400701T4 publication Critical patent/TR200400701T4/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Tibbi uygulamalar için plazmadan lgG üretimi için bir yöntem olup, en azindan asagidakileri içerir: (i') bir lgG kismina yol açacak sekilde albüminin çikarilmasi; (ii') lgG'nin bir katyon degistiriciye yüzeyden emdirilmesiyle ve yüzeyden emdirilen lgG kisminin toplanmasiyla, (i') basamaginda elde edilen lgG kismindan türetilen bir lgG kismindan lgG'nin aritilmasi ve (iii') (ii') basamaginda toplanan lgG kismindan türetilen bir lgG kisminda virüslerin etkisiz hale getirilmesi; yöntem, asagidaki özelliklere sahiptir: (I) (i') basamaginda elde edilen lgG kisminin konsantre hale getirilmesi, (II) (ii') basamaginda kullanilan katyon degistiriciden salinan lgG kisminda pH degerinin, 4 0.1'e ayarlanmasi ve tercihen yöntemin geri kalan basamaklari sirasinda pH degerinin 6.0'in asagisinda muhafaza edilmesi; ve (III) virüs etkisizlestirmenin (iii' basamagi), en azindan 4 saat boyunca 30 2 derecede kimyasallar kullanilarak gerçeklestirilmesi. DEVAMI VAR...
TR2004/00701T 2000-03-30 2001-03-29 lgG üretme yöntemi TR200400701T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0001128A SE0001128D0 (sv) 2000-03-30 2000-03-30 A method of producing IgG

Publications (1)

Publication Number Publication Date
TR200400701T4 true TR200400701T4 (tr) 2004-05-21

Family

ID=20279068

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/00701T TR200400701T4 (tr) 2000-03-30 2001-03-29 lgG üretme yöntemi

Country Status (15)

Country Link
US (1) US6835379B2 (tr)
EP (1) EP1268551B1 (tr)
JP (1) JP2003530326A (tr)
CN (1) CN1419566A (tr)
AT (1) ATE260297T1 (tr)
AU (2) AU2001273907B2 (tr)
BR (1) BRPI0109740B8 (tr)
CA (1) CA2402784A1 (tr)
DE (1) DE60102144T2 (tr)
IL (1) IL151667A0 (tr)
PT (1) PT1268551E (tr)
RU (1) RU2266914C2 (tr)
SE (1) SE0001128D0 (tr)
TR (1) TR200400701T4 (tr)
WO (1) WO2001072844A2 (tr)

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CN100451031C (zh) * 2003-09-05 2009-01-14 东丽株式会社 生物体成分组成改变了的溶液的调制方法
ATE540050T1 (de) * 2003-09-05 2012-01-15 Toray Industries Verfahren zur herstellung einer proteomanalyse- lösung
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
US7879332B2 (en) * 2005-09-01 2011-02-01 Plasma Technologies, Llc Ultra-high yield intravenous immune globulin preparation
US8293242B2 (en) * 2005-09-01 2012-10-23 Plasma Technologies, Llc Ultra-high yield of alpha-1-anti-trypsin
US20070049732A1 (en) * 2005-09-01 2007-03-01 Zurlo Eugene J Ultra-high yield intravenous immune globulin preparation
CN100362022C (zh) * 2005-11-07 2008-01-16 中国人民解放军第二军医大学 海螵蛸多糖cps-1及其制备方法和用途
US20070128693A1 (en) * 2005-12-06 2007-06-07 Advantek Serum Laboratories Limited3/F Method for the inactivation and removal of dengue virus from biological samples
WO2007136327A1 (en) * 2006-05-22 2007-11-29 Ge Healthcare Bio-Sciences Ab A method of producing igg
US20100158893A1 (en) * 2008-12-19 2010-06-24 Baxter International Inc. Systems and methods for obtaining immunoglobulin from blood
EA023382B1 (ru) 2009-05-27 2016-05-31 Бакстер Интернэшнл Инк. Способ получения высококонцентрированного препарата иммуноглобулина для подкожного применения
WO2011073235A1 (en) 2009-12-18 2011-06-23 Csl Ltd. Method of purifying polypeptides
US20130116413A1 (en) * 2009-12-29 2013-05-09 Dr. Reddy's Laboratories, Inc. Purification of proteins
ES2716088T3 (es) 2010-02-04 2019-06-10 Csl Behring Ag Preparado de inmunoglobulina
EP2361636A1 (en) 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
US8796430B2 (en) 2010-05-26 2014-08-05 Baxter International Inc. Method to produce an immunoglobulin preparation with improved yield
US8772462B2 (en) 2010-05-26 2014-07-08 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
BR112014004445B1 (pt) * 2011-08-26 2022-11-22 Takeda Pharmaceutical Company Limited Método para reduzir conteúdo de fator xi e/ou fator xia em uma composição de imunoglobulina
TWI629283B (zh) 2012-02-23 2018-07-11 巴克斯歐塔公司 來自血漿中的免疫球蛋白之ｉ-ｉｖ-１部分沉澱
US8986670B2 (en) 2012-02-29 2015-03-24 Baxter International Inc. IgG stimulated remyelination of peripheral nerves
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
FR3018450B1 (fr) * 2014-03-11 2016-04-15 Lab Francais Du Fractionnement Procede de preparation de proteines plasmatiques humaines
CN104231065A (zh) * 2014-09-09 2014-12-24 青岛康大食品有限公司 兔血中球蛋白的纯化制备方法
WO2017066683A1 (en) 2015-10-15 2017-04-20 Plasma Technologies, Llc Methods for extracting proteins from blood plasma
CA3012694A1 (en) * 2016-02-03 2017-08-10 Plasma Technologies, Llc Methods for extracting proteins from a blood-based material
US10815270B1 (en) * 2019-09-20 2020-10-27 Plasma Technologies, Llc Compositions and methods for high efficiency protein precipitation
US10836790B1 (en) * 2019-09-20 2020-11-17 Plasma Technologies, Llc Therapeutic protein compositions and methods
MX2022011950A (es) 2020-03-31 2022-10-21 Takeda Pharmaceuticals Co Metodo para producir una preparacion de inmunoglobulina a partir de plasma con reduccion del inhibidor de c-1.

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
DE3927111C3 (de) * 1989-08-17 1994-09-01 Biotest Pharma Gmbh Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oderIgA-haltiger Immunglobulinpräparate
DE59009020D1 (de) 1990-03-22 1995-06-08 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verträglichen Immunglobulin-G-Präparates.
DE4118912C1 (tr) * 1991-06-08 1992-07-02 Biotest Pharma Gmbh, 6072 Dreieich, De
ES2129076T5 (es) 1993-12-27 2003-05-16 Zlb Bioplasma Ag Procedimiento para la preparacion de un concentrado de inmunoglobulina g anti-d y composicion farmaceutica que lo contiene.
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US5886154A (en) * 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
IL121900A (en) * 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
KR100501263B1 (ko) * 1998-06-09 2005-07-18 스태튼스 세룸 인스티튜트 정맥 주사용 면역글로불린의 제조 방법 및 그 외의 면역글로불린 제품
ES2527915T3 (es) * 1998-06-09 2015-02-02 Csl Behring Ag Producto de inmunoglobulina G (IgG) líquido
DE19923027C2 (de) * 1999-05-19 2002-09-19 Aventis Behring Gmbh Verfahren zur Inaktivierung von Viren

Also Published As

Publication number Publication date
EP1268551A2 (en) 2003-01-02
PT1268551E (pt) 2004-07-30
US20030143222A1 (en) 2003-07-31
DE60102144T2 (de) 2004-10-28
SE0001128D0 (sv) 2000-03-30
BR0109740A (pt) 2003-02-04
US6835379B2 (en) 2004-12-28
DE60102144D1 (de) 2004-04-01
RU2002124857A (ru) 2004-02-20
CN1419566A (zh) 2003-05-21
ATE260297T1 (de) 2004-03-15
AU7390701A (en) 2001-10-08
BRPI0109740B8 (pt) 2021-05-25
CA2402784A1 (en) 2001-10-04
WO2001072844A2 (en) 2001-10-04
JP2003530326A (ja) 2003-10-14
EP1268551B1 (en) 2004-02-25
AU2001273907B2 (en) 2006-02-02
WO2001072844A3 (en) 2002-04-11
RU2266914C2 (ru) 2005-12-27
BR0109740B1 (pt) 2015-01-06
IL151667A0 (en) 2003-04-10

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