TR200103624T2 - Amof bileşikler ve bunların farmasötik bileşimleri. - Google Patents

Amof bileşikler ve bunların farmasötik bileşimleri.

Info

Publication number
TR200103624T2
TR200103624T2 TR2001/03624T TR200103624T TR200103624T2 TR 200103624 T2 TR200103624 T2 TR 200103624T2 TR 2001/03624 T TR2001/03624 T TR 2001/03624T TR 200103624 T TR200103624 T TR 200103624T TR 200103624 T2 TR200103624 T2 TR 200103624T2
Authority
TR
Turkey
Prior art keywords
derivatives
amof
compounds
pharmaceutical compositions
hydroxybenzoic acid
Prior art date
Application number
TR2001/03624T
Other languages
English (en)
Inventor
Benedini Francesca
Antognazza Patrizia
Original Assignee
Nicox S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox S.A. filed Critical Nicox S.A.
Publication of TR200103624T2 publication Critical patent/TR200103624T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Bu bulus, bir tadil edilmis fiziksel biçimde benzoksibenzoik asitin nitroksi türevlerine ve bu türevlerin farmasötik formülasyonlarina iliskindir, bahsedilen türevler asagidaki genel formüle sahiptir: A-X1-NO2(I), bu formülde, A, asagida tanimlandigi sekilde bir hidroksibenzoik asit türevidir, X1, asagida tanimlandigi sekilde bir baglanma iki-degerli radikalidir, bahsedilen formülasyonlar, 2-2.5 saat düzeyinde çok kisa zamanlar dahilinde, A diye tanimlanan hidroksibenzoik asit türevlerinin plazmatik konsantrasyon zirvesini uyarabilmektedir.
TR2001/03624T 1999-06-24 2000-06-21 Amof bileşikler ve bunların farmasötik bileşimleri. TR200103624T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche

Publications (1)

Publication Number Publication Date
TR200103624T2 true TR200103624T2 (tr) 2002-04-22

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03624T TR200103624T2 (tr) 1999-06-24 2000-06-21 Amof bileşikler ve bunların farmasötik bileşimleri.

Country Status (23)

Country Link
US (1) US6753442B1 (tr)
EP (1) EP1187803B1 (tr)
JP (1) JP2003503380A (tr)
KR (1) KR100672001B1 (tr)
CN (1) CN1187312C (tr)
AT (1) ATE302746T1 (tr)
AU (1) AU781479B2 (tr)
BR (1) BR0011831A (tr)
CA (1) CA2377132A1 (tr)
DE (1) DE60022188T2 (tr)
DK (1) DK1187803T3 (tr)
ES (1) ES2246878T3 (tr)
HU (1) HUP0201721A3 (tr)
IL (1) IL146789A0 (tr)
IT (1) IT1312115B1 (tr)
MX (1) MXPA01013273A (tr)
NO (1) NO321523B1 (tr)
NZ (1) NZ515757A (tr)
PL (1) PL195557B1 (tr)
RU (1) RU2248963C2 (tr)
TR (1) TR200103624T2 (tr)
WO (1) WO2001000563A1 (tr)
ZA (1) ZA200109862B (tr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020067574A (ko) 1999-12-23 2002-08-22 니트로메드 인코포레이티드 니트로소화 및 니트로실화된 사이클로옥시게나아제-2억제제, 조성물 및 그 이용방법
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
JP4092203B2 (ja) 2000-12-21 2008-05-28 ニトロメッド，インク． 新規のシクロオキシゲナーゼ２選択的阻害剤としての置換アリール化合物、組成物、および使用方法
EP1219306A1 (en) 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
EP1539134A4 (en) 2002-06-11 2007-04-11 Nitromed Inc SELECTIVE INHIBITORS OF CYCLOOXIGENASE-2 NITROSIS AND / OR NITROSYLES, COMPOSITIONS AND METHODS OF USE
US7163958B2 (en) 2002-07-03 2007-01-16 Nitromed Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
US7244753B2 (en) 2002-07-29 2007-07-17 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
ES2258760T3 (es) 2003-07-22 2006-09-01 Arena Pharmaceuticals, Inc. Derivados de diaril y de la urea de arileteroaril usados como moduladores del receptor de la serotonina 5-ht2a utiles para la profilaxis y el tratamiento de desordenes a ellos asociados.
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
JP5393677B2 (ja) 2007-08-15 2014-01-22 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ＨＴ２Ａセロトニン受容体に関連した障害の治療のための５−ＨＴ２Ａセロトニン受容体のモジュレーターとしてのイミダゾ［１，２−ａ］ピリジン誘導体
BRPI0818575A2 (pt) * 2007-10-17 2014-10-07 Todd F Ovokaitys Processo para a modificação do estado sólido de um composto e composições co-amorfas produzidas com o mesmo
CN101977888B (zh) 2007-10-17 2014-05-28 托德·F·奥沃凯泰斯 室温下稳定的非结晶阿司匹林
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
WO2009123714A2 (en) 2008-04-02 2009-10-08 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
HRP20180589T1 (hr) 2008-10-28 2018-05-18 Arena Pharmaceuticals, Inc. Pripravci modulatora serotoninskog receptora 5-ht2a koji su korisni za liječenje s njim povezanih poremećaja
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
CN102186933B (zh) 2008-11-04 2014-06-25 帝斯曼知识产权资产管理有限公司 光纤用的d 1413 ht可辐射固化涂层
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
WO2015187974A1 (en) 2014-06-06 2015-12-10 Ovokaitys Todd Frank Methods and compositions for increasing the bioactivity of nutrients
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
EP4119141A1 (en) 2015-06-12 2023-01-18 Axovant Sciences GmbH Nelotanserin for the prophylaxis and treatment of rem sleep behavior disorder
WO2017011767A2 (en) 2015-07-15 2017-01-19 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease
KR20230129426A (ko) 2020-12-08 2023-09-08 토드 프랭크 오보케이티스 줄기 세포 생산 증가를 위한 방법 및 시스템

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) * 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
WO1995030641A1 (en) * 1994-05-10 1995-11-16 Nicox S.A. Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
NO20016232D0 (no) 2001-12-19
CN1187312C (zh) 2005-02-02
NO20016232L (no) 2001-12-19
CN1356975A (zh) 2002-07-03
KR100672001B1 (ko) 2007-01-19
IT1312115B1 (it) 2002-04-04
DK1187803T3 (da) 2005-11-28
IL146789A0 (en) 2002-07-25
ES2246878T3 (es) 2006-03-01
HUP0201721A2 (en) 2002-10-28
KR20020008220A (ko) 2002-01-29
PL352529A1 (en) 2003-08-25
PL195557B1 (pl) 2007-10-31
CA2377132A1 (en) 2001-01-04
NO321523B1 (no) 2006-05-15
ITMI991402A0 (it) 1999-06-24
HUP0201721A3 (en) 2003-08-28
AU6264400A (en) 2001-01-31
ITMI991402A1 (it) 2000-12-24
ATE302746T1 (de) 2005-09-15
JP2003503380A (ja) 2003-01-28
WO2001000563A1 (en) 2001-01-04
ZA200109862B (en) 2003-05-28
DE60022188T2 (de) 2006-06-08
US6753442B1 (en) 2004-06-22
EP1187803A1 (en) 2002-03-20
EP1187803B1 (en) 2005-08-24
MXPA01013273A (es) 2003-07-14
AU781479B2 (en) 2005-05-26
BR0011831A (pt) 2002-03-19
NZ515757A (en) 2004-02-27
RU2248963C2 (ru) 2005-03-27
DE60022188D1 (de) 2005-09-29

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