TR200103624T2 - Amof bileşikler ve bunların farmasötik bileşimleri. - Google Patents

Amof bileşikler ve bunların farmasötik bileşimleri.

Info

Publication number
TR200103624T2
TR200103624T2 TR2001/03624T TR200103624T TR200103624T2 TR 200103624 T2 TR200103624 T2 TR 200103624T2 TR 2001/03624 T TR2001/03624 T TR 2001/03624T TR 200103624 T TR200103624 T TR 200103624T TR 200103624 T2 TR200103624 T2 TR 200103624T2
Authority
TR
Turkey
Prior art keywords
derivatives
amof
compounds
pharmaceutical compositions
hydroxybenzoic acid
Prior art date
Application number
TR2001/03624T
Other languages
English (en)
Inventor
Benedini Francesca
Antognazza Patrizia
Original Assignee
Nicox S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox S.A. filed Critical Nicox S.A.
Publication of TR200103624T2 publication Critical patent/TR200103624T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Bu bulus, bir tadil edilmis fiziksel biçimde benzoksibenzoik asitin nitroksi türevlerine ve bu türevlerin farmasötik formülasyonlarina iliskindir, bahsedilen türevler asagidaki genel formüle sahiptir: A-X1-NO2(I), bu formülde, A, asagida tanimlandigi sekilde bir hidroksibenzoik asit türevidir, X1, asagida tanimlandigi sekilde bir baglanma iki-degerli radikalidir, bahsedilen formülasyonlar, 2-2.5 saat düzeyinde çok kisa zamanlar dahilinde, A diye tanimlanan hidroksibenzoik asit türevlerinin plazmatik konsantrasyon zirvesini uyarabilmektedir.
TR2001/03624T 1999-06-24 2000-06-21 Amof bileşikler ve bunların farmasötik bileşimleri. TR200103624T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche

Publications (1)

Publication Number Publication Date
TR200103624T2 true TR200103624T2 (tr) 2002-04-22

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03624T TR200103624T2 (tr) 1999-06-24 2000-06-21 Amof bileşikler ve bunların farmasötik bileşimleri.

Country Status (23)

Country Link
US (1) US6753442B1 (tr)
EP (1) EP1187803B1 (tr)
JP (1) JP2003503380A (tr)
KR (1) KR100672001B1 (tr)
CN (1) CN1187312C (tr)
AT (1) ATE302746T1 (tr)
AU (1) AU781479B2 (tr)
BR (1) BR0011831A (tr)
CA (1) CA2377132A1 (tr)
DE (1) DE60022188T2 (tr)
DK (1) DK1187803T3 (tr)
ES (1) ES2246878T3 (tr)
HU (1) HUP0201721A3 (tr)
IL (1) IL146789A0 (tr)
IT (1) IT1312115B1 (tr)
MX (1) MXPA01013273A (tr)
NO (1) NO321523B1 (tr)
NZ (1) NZ515757A (tr)
PL (1) PL195557B1 (tr)
RU (1) RU2248963C2 (tr)
TR (1) TR200103624T2 (tr)
WO (1) WO2001000563A1 (tr)
ZA (1) ZA200109862B (tr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2002119574A (ru) 1999-12-23 2004-01-10 Нитромед, Инк. (Us) Нитрозированные и нитрозилированные ингибиторы циклооксигеназы-2, композиции на их основе и способы их применения
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
AU2002249812B2 (en) 2000-12-21 2005-11-10 Nicox S.A. Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
WO2003103602A2 (en) 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
WO2004004648A2 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
JP2005538110A (ja) 2002-07-29 2005-12-15 ニトロメッド インコーポレーティッド シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法
TW200523253A (en) 2003-07-22 2005-07-16 Arena Pharm Inc Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
EP2190844B3 (en) 2007-08-15 2013-07-17 Arena Pharmaceuticals, Inc. Imidazo[1,2-a]pyridine derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
US8173632B2 (en) 2007-10-17 2012-05-08 Todd F. Ovokaitys Process for the modification of the solid state of a compound and co-amorphous compositions produced with same
US8377989B2 (en) * 2007-10-17 2013-02-19 Todd F. Ovokaitys Room temperature stable non-crystalline aspirin and method for the preparation thereof
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
EP2364142B1 (en) 2008-10-28 2018-01-17 Arena Pharmaceuticals, Inc. Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
JP5392868B2 (ja) 2008-11-04 2014-01-22 ディーエスエム アイピー アセッツ ビー．ブイ． 光ファイバ用ｄ１４１３ｈｔ放射線硬化性コーティング
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
US10040728B2 (en) 2014-06-06 2018-08-07 Todd Frank Ovokaitys Methods and compositions for increasing the bioactivity of nutrients
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
WO2016201373A1 (en) 2015-06-12 2016-12-15 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
AU2016291673A1 (en) 2015-07-15 2018-01-25 Axovant Sciences Gmbh Diaryl and arylheteroaryl urea derivatives for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease
CA3201604A1 (en) 2020-12-08 2022-06-16 Todd Frank OVOKAITYS Methods and systems for increased production of stem cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) * 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
EP0759899B1 (en) * 1994-05-10 1999-09-15 Nicox S.A. Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
WO2001000563A1 (en) 2001-01-04
DE60022188T2 (de) 2006-06-08
AU781479B2 (en) 2005-05-26
HUP0201721A2 (en) 2002-10-28
CA2377132A1 (en) 2001-01-04
RU2248963C2 (ru) 2005-03-27
JP2003503380A (ja) 2003-01-28
PL195557B1 (pl) 2007-10-31
MXPA01013273A (es) 2003-07-14
ATE302746T1 (de) 2005-09-15
US6753442B1 (en) 2004-06-22
IL146789A0 (en) 2002-07-25
NO321523B1 (no) 2006-05-15
ES2246878T3 (es) 2006-03-01
IT1312115B1 (it) 2002-04-04
DE60022188D1 (de) 2005-09-29
AU6264400A (en) 2001-01-31
KR100672001B1 (ko) 2007-01-19
CN1356975A (zh) 2002-07-03
EP1187803B1 (en) 2005-08-24
ITMI991402A0 (it) 1999-06-24
DK1187803T3 (da) 2005-11-28
KR20020008220A (ko) 2002-01-29
ITMI991402A1 (it) 2000-12-24
HUP0201721A3 (en) 2003-08-28
EP1187803A1 (en) 2002-03-20
PL352529A1 (en) 2003-08-25
BR0011831A (pt) 2002-03-19
CN1187312C (zh) 2005-02-02
ZA200109862B (en) 2003-05-28
NZ515757A (en) 2004-02-27
NO20016232D0 (no) 2001-12-19
NO20016232L (no) 2001-12-19

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