ZA200109862B - Amorphous nitric esters and their pharmaceutical compositions. - Google Patents
Amorphous nitric esters and their pharmaceutical compositions.Info
- Publication number
- ZA200109862B ZA200109862B ZA200109862A ZA200109862A ZA200109862B ZA 200109862 B ZA200109862 B ZA 200109862B ZA 200109862 A ZA200109862 A ZA 200109862A ZA 200109862 A ZA200109862 A ZA 200109862A ZA 200109862 B ZA200109862 B ZA 200109862B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutical compositions
- nitric esters
- amorphous
- amorphous nitric
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C203/00—Esters of nitric or nitrous acid
- C07C203/02—Esters of nitric acid
- C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI001402A IT1312115B1 (it) | 1999-06-24 | 1999-06-24 | Composti amorfi e relative composizioni farmaceutiche |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200109862B true ZA200109862B (en) | 2003-05-28 |
Family
ID=11383219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200109862A ZA200109862B (en) | 1999-06-24 | 2001-11-29 | Amorphous nitric esters and their pharmaceutical compositions. |
Country Status (23)
Country | Link |
---|---|
US (1) | US6753442B1 (xx) |
EP (1) | EP1187803B1 (xx) |
JP (1) | JP2003503380A (xx) |
KR (1) | KR100672001B1 (xx) |
CN (1) | CN1187312C (xx) |
AT (1) | ATE302746T1 (xx) |
AU (1) | AU781479B2 (xx) |
BR (1) | BR0011831A (xx) |
CA (1) | CA2377132A1 (xx) |
DE (1) | DE60022188T2 (xx) |
DK (1) | DK1187803T3 (xx) |
ES (1) | ES2246878T3 (xx) |
HU (1) | HUP0201721A3 (xx) |
IL (1) | IL146789A0 (xx) |
IT (1) | IT1312115B1 (xx) |
MX (1) | MXPA01013273A (xx) |
NO (1) | NO321523B1 (xx) |
NZ (1) | NZ515757A (xx) |
PL (1) | PL195557B1 (xx) |
RU (1) | RU2248963C2 (xx) |
TR (1) | TR200103624T2 (xx) |
WO (1) | WO2001000563A1 (xx) |
ZA (1) | ZA200109862B (xx) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1319202B1 (it) | 2000-10-12 | 2003-09-26 | Nicox Sa | Farmaci per le malattie a base infiammatoria. |
CA2432642A1 (en) | 2000-12-21 | 2002-08-08 | Subhash P. Khanapure | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use |
EP1219306A1 (en) | 2000-12-29 | 2002-07-03 | Nicox S.A. | Compositions comprising cyclodextrins and NO- releasing drugs |
JP2006501161A (ja) | 2002-06-11 | 2006-01-12 | ニトロメッド インク. | ニトロソ化および/またはニトロシル化シクロオキシゲナーゼ−2選択的阻害剤、組成物ならびに使用方法 |
AU2003247792B2 (en) | 2002-07-03 | 2009-09-24 | Nicox S.A. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
CA2493156A1 (en) | 2002-07-29 | 2004-02-05 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
WO2005012254A1 (en) | 2003-07-22 | 2005-02-10 | Arena Pharmaceuticals, Inc. | Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related therto |
TWI415845B (zh) | 2006-10-03 | 2013-11-21 | Arena Pharm Inc | 用於治療與5-ht2a血清素受體相關聯病症之作為5-ht2a血清素受體之調節劑的吡唑衍生物 |
EP2190844B3 (en) | 2007-08-15 | 2013-07-17 | Arena Pharmaceuticals, Inc. | Imidazo[1,2-a]pyridine derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto |
EA023338B1 (ru) * | 2007-10-17 | 2016-05-31 | Тодд Ф. Овокайтис | Способ модификации твердого состояния соединения и соаморфные композиции, полученные этим способом |
EA027333B1 (ru) * | 2007-10-17 | 2017-07-31 | Тодд Ф. Овокайтис | Стабильный при комнатной температуре некристаллический аспирин |
ES2324007A1 (es) * | 2007-10-25 | 2009-07-28 | Ferrer Internacional, S.A. | Una forma amorfa de un compuesto antiinflamatorio. |
WO2009123714A2 (en) | 2008-04-02 | 2009-10-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
US9126946B2 (en) | 2008-10-28 | 2015-09-08 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto |
SI2364142T1 (en) * | 2008-10-28 | 2018-06-29 | Arena Pharmaceuticals, Inc. | The modulators of the serotonin 5-HT2A receptor are useful in the treatment of disorders associated with it |
CN102186933B (zh) | 2008-11-04 | 2014-06-25 | 帝斯曼知识产权资产管理有限公司 | 光纤用的d 1413 ht可辐射固化涂层 |
US10202598B2 (en) | 2014-05-30 | 2019-02-12 | Todd Frank Ovokaitys | Methods and systems for generation, use, and delivery of activated stem cells |
WO2015187974A1 (en) | 2014-06-06 | 2015-12-10 | Ovokaitys Todd Frank | Methods and compositions for increasing the bioactivity of nutrients |
US10384985B2 (en) | 2014-06-06 | 2019-08-20 | B.K. Consultants, Inc. | Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants |
MX2017016413A (es) | 2015-06-12 | 2018-08-01 | Axovant Sciences Gmbh | Derivados de diaril y arilheteroaril urea como moduladores del receptor 5ht2a de serotonina útiles para la profilaxis y el tratamineto de un trastorno conductual del sueño rem. |
MX2018000465A (es) | 2015-07-15 | 2018-09-17 | Axovant Sciences Gmbh | Derivados de diaril y arilheteroaril urea como moduladores del receptor de serotonina 5-ht2a útiles para la profilaxis y el tratamiento de alucinaciones asociadas con una enfermedad neurodegenerativa. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1243367B (it) * | 1990-07-26 | 1994-06-10 | Italfarmaco Spa | Derivati acidi benzoici sostituiti ad attivita' cardiovascolare |
IT1256345B (it) * | 1992-08-20 | 1995-12-01 | Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione | |
IT1256450B (it) * | 1992-11-26 | 1995-12-05 | Soldato Piero Del | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione |
CA2190087C (en) * | 1994-05-10 | 2005-08-02 | Piero Del Soldato | Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic activities |
IT1276071B1 (it) * | 1995-10-31 | 1997-10-24 | Nicox Ltd | Compositi ad attivita' anti-infiammatoria |
KR19990001564A (ko) * | 1997-06-16 | 1999-01-15 | 유충식 | 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제 |
IT1307928B1 (it) | 1999-01-26 | 2001-11-29 | Nicox Sa | Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina. |
-
1999
- 1999-06-24 IT IT1999MI001402A patent/IT1312115B1/it active
-
2000
- 2000-06-21 AU AU62644/00A patent/AU781479B2/en not_active Ceased
- 2000-06-21 EP EP00949202A patent/EP1187803B1/en not_active Expired - Lifetime
- 2000-06-21 PL PL00352529A patent/PL195557B1/pl unknown
- 2000-06-21 US US10/009,741 patent/US6753442B1/en not_active Expired - Fee Related
- 2000-06-21 IL IL14678900A patent/IL146789A0/xx not_active IP Right Cessation
- 2000-06-21 BR BR0011831-1A patent/BR0011831A/pt not_active Application Discontinuation
- 2000-06-21 DK DK00949202T patent/DK1187803T3/da active
- 2000-06-21 AT AT00949202T patent/ATE302746T1/de not_active IP Right Cessation
- 2000-06-21 NZ NZ515757A patent/NZ515757A/xx unknown
- 2000-06-21 HU HU0201721A patent/HUP0201721A3/hu unknown
- 2000-06-21 TR TR2001/03624T patent/TR200103624T2/xx unknown
- 2000-06-21 CA CA002377132A patent/CA2377132A1/en not_active Abandoned
- 2000-06-21 JP JP2001506976A patent/JP2003503380A/ja active Pending
- 2000-06-21 RU RU2001134613/04A patent/RU2248963C2/ru not_active IP Right Cessation
- 2000-06-21 CN CNB008091919A patent/CN1187312C/zh not_active Expired - Fee Related
- 2000-06-21 ES ES00949202T patent/ES2246878T3/es not_active Expired - Lifetime
- 2000-06-21 KR KR1020017015729A patent/KR100672001B1/ko not_active IP Right Cessation
- 2000-06-21 MX MXPA01013273A patent/MXPA01013273A/es active IP Right Grant
- 2000-06-21 WO PCT/EP2000/005723 patent/WO2001000563A1/en active IP Right Grant
- 2000-06-21 DE DE60022188T patent/DE60022188T2/de not_active Expired - Fee Related
-
2001
- 2001-11-29 ZA ZA200109862A patent/ZA200109862B/xx unknown
- 2001-12-19 NO NO20016232A patent/NO321523B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
ITMI991402A1 (it) | 2000-12-24 |
PL195557B1 (pl) | 2007-10-31 |
HUP0201721A3 (en) | 2003-08-28 |
KR20020008220A (ko) | 2002-01-29 |
ES2246878T3 (es) | 2006-03-01 |
ITMI991402A0 (it) | 1999-06-24 |
AU781479B2 (en) | 2005-05-26 |
MXPA01013273A (es) | 2003-07-14 |
KR100672001B1 (ko) | 2007-01-19 |
DE60022188T2 (de) | 2006-06-08 |
BR0011831A (pt) | 2002-03-19 |
EP1187803B1 (en) | 2005-08-24 |
NZ515757A (en) | 2004-02-27 |
CN1356975A (zh) | 2002-07-03 |
EP1187803A1 (en) | 2002-03-20 |
NO321523B1 (no) | 2006-05-15 |
JP2003503380A (ja) | 2003-01-28 |
NO20016232D0 (no) | 2001-12-19 |
DE60022188D1 (de) | 2005-09-29 |
AU6264400A (en) | 2001-01-31 |
US6753442B1 (en) | 2004-06-22 |
HUP0201721A2 (en) | 2002-10-28 |
IT1312115B1 (it) | 2002-04-04 |
CA2377132A1 (en) | 2001-01-04 |
RU2248963C2 (ru) | 2005-03-27 |
NO20016232L (no) | 2001-12-19 |
TR200103624T2 (tr) | 2002-04-22 |
IL146789A0 (en) | 2002-07-25 |
ATE302746T1 (de) | 2005-09-15 |
DK1187803T3 (da) | 2005-11-28 |
CN1187312C (zh) | 2005-02-02 |
WO2001000563A1 (en) | 2001-01-04 |
PL352529A1 (en) | 2003-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL146789A0 (en) | Amorphous nitric esters and their pharmaceutical compositions | |
HUP0105113A3 (en) | Benzoheterocycles and their use as mek inhibitors and pharmaceutical compositions containing the compounds | |
IL150223A0 (en) | Lipopeptides and pharmaceutical compositions containing the same | |
HUP0302412A3 (en) | Betha-carboline derivatives useful as inhibitors of phosphodiesterase and pharmaceutical compositions containing the same | |
HUP0302922A3 (en) | Imidazolo-5-yl-2-anilino-pyrimidines as agents for the inhibition of the cell proliferation and pharmaceutical compositions containing them | |
HUP0201011A2 (en) | Aminopyrimidines as sorbitol dehydrogenase inhibitors and pharmaceutical compositions containing them | |
AU2001290257A1 (en) | Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same | |
AU2001290257A2 (en) | Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same | |
IL156558A0 (en) | Novel quinuclidine derivatives and medicinal compositions containing the same | |
IL151372A0 (en) | Cyclopropyl-fused pyrrolidine derivatives and pharmaceutical compositions containing the same | |
HK1061037A1 (en) | Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same | |
HUP0204071A3 (en) | Nitrogenous cyclic compounds and pharmaceutical compositions containing the same and their use | |
IL152718A0 (en) | Piperidine derivatives and pharmaceutical compositions containing the same | |
IL152451A0 (en) | 2-chloro-2-nitrophenylcarboxamide derivatives and pharmaceutical compositions containing the same | |
HUP0301472A3 (en) | Carbamate caspase inhibitors and uses thereof and pharmaceutical compositions containing them | |
IL153123A0 (en) | N-ureidoheterocycloalkyl-piperidine derivatives and pharmaceutical compositions containing the same | |
AU2001236457A1 (en) | Compounds and compositions for delivering active agents | |
HK1053107A1 (zh) | 作為jnk抗化劑的pyrazoloanthrone及其衍生物和它們的成份 | |
AU2001284985A1 (en) | Compounds and compositions for delivering active agents | |
DK1246625T3 (da) | Anvendelser og sammensætninger af nitratestere til tilvejebringelse af sedering | |
EP1311477A4 (en) | NEW THIOCARBAMIDIC ACID DERIVATIVES AND MEDICAMENTS CONTAINING THEM | |
HUP0103382A3 (en) | Naaladase inhibitors useful as pharmaceutical compounds and compositions | |
IL162325A0 (en) | Hiv integrase inhibitor compounds and pharmaceutical compositions containing the same | |
AP2003002716A0 (en) | Medicinal compositions containing propenone derivatives. | |
HUP0203787A3 (en) | Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent, pharmaceutical compositions containing them and their use |