BRPI0408240A - composto, utilização de um composto e composição farmacêutica - Google Patents
composto, utilização de um composto e composição farmacêuticaInfo
- Publication number
- BRPI0408240A BRPI0408240A BRPI0408240-0A BRPI0408240A BRPI0408240A BR PI0408240 A BRPI0408240 A BR PI0408240A BR PI0408240 A BRPI0408240 A BR PI0408240A BR PI0408240 A BRPI0408240 A BR PI0408240A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- carbon
- pharmaceutical composition
- hydrogen
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
"COMPOSTO, UTILIZAçãO DE UM COMPOSTO E COMPOSIçãO FARMACêUTICA". Composto de fórmula I em que X = O ou grupamento N-OH, R representa um grupamento escolhido dentre o A = hidrogênio ou junto com B uma ligação carbono-carbono, B = hidrogênio, hidróxi ou junto com A uma ligação carbono-carbono, C, D, E, F = hidrogênio ou junto com D uma ligação carbono-carbono, ou um de seus sais de aditivo com os ácidos farmaceuticamente aceitáveis, com a exceção de alguns compostos, a título de medicamento, aplicação notadamente como neuroprotetores, novos compostos de fórmula I e composições farmacêuticas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0302992A FR2852246B1 (fr) | 2003-03-11 | 2003-03-11 | Utilisation de l'oxime de cholest-4-en-3-one dans le traitement des affections du motoneurone |
FR0311324A FR2860159B1 (fr) | 2003-09-26 | 2003-09-26 | Utilisation de l'oxime de cholest-4-en-3-one en tant que medicament neuroprotecteur |
PCT/FR2004/000532 WO2004082581A2 (fr) | 2003-03-11 | 2004-03-05 | Application a titre de medicaments de derives de cholest-4-en-3- one, compositions pharmaceutiques les renfermant et nouveaux derives |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0408240A true BRPI0408240A (pt) | 2006-03-01 |
Family
ID=33031360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0408240-0A BRPI0408240A (pt) | 2003-03-11 | 2004-03-05 | composto, utilização de um composto e composição farmacêutica |
Country Status (12)
Country | Link |
---|---|
US (4) | US7858603B2 (pt) |
EP (1) | EP1601363B1 (pt) |
JP (1) | JP4970932B2 (pt) |
AU (1) | AU2004222540B2 (pt) |
BR (1) | BRPI0408240A (pt) |
CA (1) | CA2517893C (pt) |
DK (1) | DK1601363T3 (pt) |
ES (1) | ES2388669T3 (pt) |
IL (1) | IL170348A (pt) |
PL (1) | PL1601363T3 (pt) |
PT (1) | PT1601363E (pt) |
WO (1) | WO2004082581A2 (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2874923B1 (fr) * | 2004-09-07 | 2006-10-27 | Trophos Sa | Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation |
FR2894968B1 (fr) * | 2005-12-20 | 2008-02-22 | Trophos Sa | Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation |
FR2899108B1 (fr) * | 2006-03-31 | 2012-02-03 | Trophos | Utilisation de derives du cholest-4-en-3-one pour l'obtention d'un medicament cytoprotecteur |
FR2907783A1 (fr) * | 2006-10-30 | 2008-05-02 | Trophos Sa | Nouveaux composes chimiques, leurs procedes de synthese et leur utilisation a titre de medicament, particulierement a titre de medicament cytoprotecteur, neuroprotecteur ou cardioprotecteur |
FR2914188B1 (fr) * | 2007-03-28 | 2012-06-22 | Trophos | Nouvelle composition a base d'oxime de cholest-4-en-3-one |
US20080275259A1 (en) * | 2007-05-04 | 2008-11-06 | Scinopharm Taiwan, Ltd | Process for preparing aromatase inhibitors |
AR061892A1 (es) * | 2007-07-11 | 2008-10-01 | Consejo Nac Invest Cient Tec | Un compuesto que presenta actividad antiinflamatoria y actividad antiviral, composiciones farmaceuticas que lo comprenden, un procedimiento para su obtencion y uso del mismo en el tratamiento de la queratoconjuntivitis epidemica y de la queratitis estromal herpetica |
FR2919180B1 (fr) * | 2007-07-25 | 2009-11-27 | Trophos | Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants |
NZ584849A (en) * | 2007-10-30 | 2012-04-27 | Trophos | Novel composition for treating the side effects of anticancer treatments |
WO2009108804A2 (en) * | 2008-02-26 | 2009-09-03 | Emory University | Steroid analogues for neuroprotection |
FR2934596B1 (fr) * | 2008-07-30 | 2015-04-10 | Trophos | Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation |
CN101619089B (zh) * | 2009-07-28 | 2011-07-20 | 陈大刚 | 抗肿瘤药物cl168、其合成方法及应用 |
DK2556055T3 (da) | 2010-04-09 | 2019-08-19 | The Research Foundation Of The State Univ Of New York | Ship-hæmmere og anvendelser deraf |
WO2012069150A2 (en) | 2010-11-22 | 2012-05-31 | Powerpore Gmbh | Cytoprotectant agents for the prevention of drug-associated side-effects |
FR2979239A1 (fr) | 2011-08-25 | 2013-03-01 | Trophos | Liposome comprenant au moins un derive de cholesterol |
US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
EP3978507A1 (en) * | 2013-08-12 | 2022-04-06 | Emory University | Progesterone phosphate analogs and uses related thereto |
EP3297650A1 (en) * | 2015-05-20 | 2018-03-28 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for treating peripheral demyelinating diseases |
WO2017080967A1 (en) | 2015-11-12 | 2017-05-18 | F. Hoffmann-La Roche Ag | Compositions for treating spinal muscular atrophy |
JP2019517516A (ja) | 2016-06-03 | 2019-06-24 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Smaの新規な処置 |
WO2018073141A1 (en) | 2016-10-18 | 2018-04-26 | F. Hoffmann-La Roche Ag | New composition for treating sma |
CN108938648A (zh) * | 2018-06-21 | 2018-12-07 | 中山大学 | 胆甾-3,6-二酮用于神经元损伤的治疗 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52116456A (en) * | 1976-03-25 | 1977-09-29 | Takasago Corp | Preparation of 3-keto- #4-steroid |
DE4004920C1 (pt) * | 1990-02-16 | 1991-09-19 | Kanoldt Arzneimittel Gmbh, 8884 Hoechstaedt, De | |
US5264428A (en) * | 1990-02-16 | 1993-11-23 | Kanoldt Arzneimittel Gmbh | Use of stigmasta-4-en-3-one in the treatment of androgen dependent diseases |
JPH0748397A (ja) * | 1993-08-05 | 1995-02-21 | Taisho Pharmaceut Co Ltd | ステロイド化合物 |
ATE156836T1 (de) * | 1994-05-19 | 1997-08-15 | Akzo Nobel Nv | 11,21-bisphenyl-19-nor-pregnan derivate |
JP2001031572A (ja) * | 1999-07-22 | 2001-02-06 | Kyorin Pharmaceut Co Ltd | ジクチオステロールを有効成分とする中枢神経細胞突起再生薬 |
DE19961219A1 (de) * | 1999-12-15 | 2001-07-19 | Jenapharm Gmbh | 11beta-Phenylestratrien-Derivate mit Fluoralkylgruppen in der aromatischen Seitenkette, deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
JP2002030096A (ja) * | 2000-07-11 | 2002-01-29 | Kyorin Pharmaceut Co Ltd | 神経細胞突起再生剤及びその製造方法 |
-
2004
- 2004-03-05 DK DK04717660.7T patent/DK1601363T3/da active
- 2004-03-05 BR BRPI0408240-0A patent/BRPI0408240A/pt not_active Application Discontinuation
- 2004-03-05 PL PL04717660T patent/PL1601363T3/pl unknown
- 2004-03-05 JP JP2006505701A patent/JP4970932B2/ja not_active Expired - Lifetime
- 2004-03-05 US US10/548,473 patent/US7858603B2/en not_active Expired - Fee Related
- 2004-03-05 PT PT04717660T patent/PT1601363E/pt unknown
- 2004-03-05 EP EP04717660A patent/EP1601363B1/fr not_active Expired - Lifetime
- 2004-03-05 ES ES04717660T patent/ES2388669T3/es not_active Expired - Lifetime
- 2004-03-05 CA CA2517893A patent/CA2517893C/fr not_active Expired - Fee Related
- 2004-03-05 WO PCT/FR2004/000532 patent/WO2004082581A2/fr active Application Filing
- 2004-03-05 AU AU2004222540A patent/AU2004222540B2/en not_active Ceased
-
2005
- 2005-08-18 IL IL170348A patent/IL170348A/en active IP Right Grant
-
2010
- 2010-05-07 US US12/776,217 patent/US8283341B2/en not_active Expired - Fee Related
-
2012
- 2012-08-22 US US13/591,789 patent/US8354395B2/en not_active Expired - Fee Related
- 2012-08-22 US US13/591,774 patent/US8575138B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IL170348A (en) | 2014-02-27 |
EP1601363A2 (fr) | 2005-12-07 |
AU2004222540A1 (en) | 2004-09-30 |
US20120316141A1 (en) | 2012-12-13 |
US20100216752A1 (en) | 2010-08-26 |
ES2388669T3 (es) | 2012-10-17 |
EP1601363B1 (fr) | 2012-06-20 |
US8354395B2 (en) | 2013-01-15 |
US20120309721A1 (en) | 2012-12-06 |
WO2004082581A2 (fr) | 2004-09-30 |
DK1601363T3 (da) | 2012-09-03 |
US8283341B2 (en) | 2012-10-09 |
US8575138B2 (en) | 2013-11-05 |
US20060217358A1 (en) | 2006-09-28 |
PL1601363T3 (pl) | 2012-11-30 |
CA2517893C (fr) | 2012-05-15 |
PT1601363E (pt) | 2012-08-17 |
CA2517893A1 (fr) | 2004-09-30 |
US7858603B2 (en) | 2010-12-28 |
WO2004082581A3 (fr) | 2004-10-28 |
AU2004222540B2 (en) | 2009-10-01 |
JP4970932B2 (ja) | 2012-07-11 |
JP2006519819A (ja) | 2006-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0408240A (pt) | composto, utilização de um composto e composição farmacêutica | |
BR0214343A (pt) | Inibidores de 11 - beta - hidroxi esteróide desidrogenase tipo 1 | |
DE60142891D1 (de) | Azetidinderivate enthaltende pharmazeutische zusammensetzungen, die azetidinderivate und deren herstellung | |
NO20085064L (no) | 4,5-difenyl-pyrimidinyl-oksy eller -merkaptosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter | |
BR0010555A (pt) | Inibidores de neuraminidases | |
BRPI0621386B8 (pt) | composição farmacêutica para o uso externo | |
BRPI0407810A (pt) | composto, composição farmacêutica, ativador da glicocinase, e, medicamento | |
BRPI0809977A8 (pt) | Uso de um composto, compostos e composição farmacêutica que o contém | |
BRPI0715579A2 (pt) | "composto, composição farmacêutica e uso de um composto" | |
TW200628161A (en) | Novel betulin derivatives, preparation thereof and use thereof | |
BRPI0714885B8 (pt) | compostos terapêuticos e seu uso | |
BRPI0507830A (pt) | derivados azabicìclicos, o respectivo processo de preparo e as composições farmacêuticas que os contêm | |
AR055319A1 (es) | Derivados de isoquinoleina, composiciones farmaceuticas y usos | |
UY29169A1 (es) | Derivados de 2-amido-4 feniltiazol, su preparacion y su aplicacion en terapeutica | |
AR054129A1 (es) | Derivados de 2, 6-quinolinilo, una preparacion farmaceutica que los contiene y su empleo en la fabricacion de medicamentos para el tratamiento de enfermedades dependientes de integrinas alfa4beta1 y/o alfa4beta7 | |
BRPI0417157A (pt) | composto, composição farmacêutica, e, uso de um composto ou de uma composição farmacêutica | |
TR200103624T2 (tr) | Amof bileşikler ve bunların farmasötik bileşimleri. | |
BRPI0417858A (pt) | composto, composição farmacêutica, e, uso de uma composição farmacêutica | |
BR0314352A (pt) | Indóis 2,7-substituìdos e seu uso como moduladores de 5-ht6 | |
PL1970372T3 (pl) | Sole kwasu 9-oksoakrydyno-10-octowego z 1-alkiloamino-1-deoksypoliolami | |
ES2151698T3 (es) | Nuevos derivados de 6-hidroxi y 6-oxo-androstan activos sobre el sistema cardiovascular y composiciones farmaceuticas que los contienen. | |
UY30356A1 (es) | Derivados de 3-halo-n-(2.(4-fluorofenil)-4-oxobutil)-n-metil-5-(trifluorometil)benzamida y composiciones de los mismos. | |
BR112012009311A2 (pt) | composto, composição farmacêutica, e, uso do composto | |
BR9810567A (pt) | Composições antimicrobianas sinérgicas contendo uma dimetilamida de um ácido carboxìlico com uma mistura de 2-(tiocianometiltio) benzotiazol e um metileno-bis (tiocianato) e uso destes | |
BRPI0302496B8 (pt) | composições farmacêuticas com atividade antibiótica |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |