ATE156836T1 - 11,21-bisphenyl-19-nor-pregnan derivate - Google Patents
11,21-bisphenyl-19-nor-pregnan derivateInfo
- Publication number
- ATE156836T1 ATE156836T1 AT95201268T AT95201268T ATE156836T1 AT E156836 T1 ATE156836 T1 AT E156836T1 AT 95201268 T AT95201268 T AT 95201268T AT 95201268 T AT95201268 T AT 95201268T AT E156836 T1 ATE156836 T1 AT E156836T1
- Authority
- AT
- Austria
- Prior art keywords
- nr5r6
- alkyl
- bisphenyl
- son
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Seasonings (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94201431 | 1994-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE156836T1 true ATE156836T1 (de) | 1997-08-15 |
Family
ID=8216894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95201268T ATE156836T1 (de) | 1994-05-19 | 1995-05-16 | 11,21-bisphenyl-19-nor-pregnan derivate |
Country Status (20)
Country | Link |
---|---|
US (1) | US5620966A (de) |
EP (1) | EP0683172B1 (de) |
JP (1) | JP3814312B2 (de) |
KR (1) | KR100359474B1 (de) |
CN (1) | CN1042539C (de) |
AT (1) | ATE156836T1 (de) |
AU (1) | AU701616B2 (de) |
BR (1) | BR9502085A (de) |
CA (1) | CA2149496C (de) |
DE (1) | DE69500542T2 (de) |
DK (1) | DK0683172T3 (de) |
ES (1) | ES2106616T3 (de) |
FI (1) | FI112491B (de) |
GR (1) | GR3025225T3 (de) |
HU (1) | HU217429B (de) |
NO (1) | NO304379B1 (de) |
NZ (1) | NZ272143A (de) |
PL (1) | PL180481B1 (de) |
RU (1) | RU2152952C2 (de) |
ZA (1) | ZA953976B (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
AP1542A (en) | 1999-04-30 | 2006-01-31 | Pfizer Prod Inc | Glucocorticoid receptor modulators. |
US7713989B2 (en) | 2000-04-27 | 2010-05-11 | Dow Robert L | Glucocorticoid receptor modulators |
ES2246292T3 (es) | 2000-10-30 | 2006-02-16 | Pfizer Products Inc. | Moduladores de receptor glucocorticoide. |
EP1285927A3 (de) | 2001-08-16 | 2005-06-29 | Schering Aktiengesellschaft | Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems |
US8193172B2 (en) | 2001-11-23 | 2012-06-05 | Pop Test Cortisol Llc | Methods for the treatment of major depressive disorder using glucocorticoid receptor antagonists |
US7250408B2 (en) | 2002-12-16 | 2007-07-31 | Bayer Schering Pharma Ag | Glucocorticoid receptor antagonists for prophylaxis and therapy of glucocorticoid-mediated hypogonadism, of sexual dysfunction and/or infertility |
AU2004222540B2 (en) * | 2003-03-11 | 2009-10-01 | Trophos | Use of derivatives of cholest-4-en-3-one as medicaments, pharmaceutical compositions containing same, novel derivatives and preparation method thereof |
DK2054049T3 (en) | 2006-08-24 | 2016-08-01 | Univ Tennessee Res Found | SUBSTITUTED ACYLANILIDES AND PROCEDURES FOR USING THEREOF |
US10314807B2 (en) | 2012-07-13 | 2019-06-11 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US10987334B2 (en) | 2012-07-13 | 2021-04-27 | University Of Tennessee Research Foundation | Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs) |
US10258596B2 (en) | 2012-07-13 | 2019-04-16 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US9744149B2 (en) | 2012-07-13 | 2017-08-29 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
KR102238970B1 (ko) | 2012-07-13 | 2021-04-09 | 지티엑스, 인코포레이티드 | 선택적 안드로겐 수용체 조절자(sarms)를 이용한 안드로겐 수용체(ar) 양성 유방암의 치료 방법 |
US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
EP3265127B1 (de) | 2015-03-02 | 2024-02-21 | Corcept Therapeutics, Inc. | Mifepriston und octreotid zur verwendung bei der behandlung des cushing-syndroms bei einem patienten mit einem adrenocorticotropen hormon (acth) sezernierenden pankreatischen neuroendokrinen tumor |
ES2906778T3 (es) | 2015-03-30 | 2022-04-20 | Corcept Therapeutics Inc | Uso de antagonistas del receptor de glucocorticoides en combinación con glucocorticoides para tratar la insuficiencia suprarrenal |
JP6768789B2 (ja) | 2015-08-13 | 2020-10-14 | コーセプト セラピューティクス, インコーポレイテッド | Acth依存性クッシング症候群を鑑別診断する方法 |
CN105254697A (zh) * | 2015-11-17 | 2016-01-20 | 湖南成大生物科技有限公司 | △16甾体类化合物的制备方法 |
EP3405101B1 (de) | 2016-01-19 | 2020-12-23 | Corcept Therapeutics, Inc. | Differentialdiagnose von ektopischem cushing-syndrom |
EP3214092A1 (de) * | 2016-03-04 | 2017-09-06 | Bayer Pharma Aktiengesellschaft | Prodrugs vom selektiven progesteronrezeptormodulator (sprm) (11.beta.,17.beta.)-17-hydroxy-11-[4-(methylsulphonyl)phenyl]-17-(pentafluoroethyl)estra-4,9-dien-3-on |
EP3641780A4 (de) | 2017-06-20 | 2021-02-24 | Corcept Therapeutics, Inc. | Verfahren zur behandlung von neuroepitheltumoren unter verwendung selektiver glucocorticoidrezeptormodulatoren |
CN114456223B (zh) * | 2022-01-24 | 2023-07-21 | 湖南科益新生物医药有限公司 | 3-缩酮的合成方法 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2528434B1 (fr) * | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
FR2522328B1 (fr) * | 1982-03-01 | 1986-02-14 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
FR2639045B2 (fr) * | 1982-03-01 | 1994-07-29 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto-delta-4,9-19-nor steroides et leur application comme medicaments |
EP0116974B1 (de) * | 1983-02-18 | 1986-10-29 | Schering Aktiengesellschaft | 11-Beta-Aryl-Estradiene, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
FR2549067B1 (fr) * | 1983-06-14 | 1985-12-27 | Roussel Uclaf | Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques |
US4780461A (en) * | 1983-06-15 | 1988-10-25 | Schering Aktiengesellschaft | 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same |
DE3347126A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
DE3410880A1 (de) * | 1984-03-21 | 1985-10-03 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 17-substituierte estradiene und estratriene |
DE3506785A1 (de) * | 1985-02-22 | 1986-08-28 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 11ss-n,n-dimethylaminophenyl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
US4771042A (en) * | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
FR2598421B1 (fr) | 1986-05-06 | 1988-08-19 | Roussel Uclaf | Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
DE3625315A1 (de) * | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
US4774236A (en) * | 1986-09-17 | 1988-09-27 | Research Triangle Institute | 17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them |
ES2053714T3 (es) * | 1987-12-12 | 1994-08-01 | Akzo Nv | Proceso para la preparacion de 11-arilesteroides. |
JP2785023B2 (ja) * | 1987-12-30 | 1998-08-13 | ルセル―ユクラフ | 17α位置を置換された17β―OH―19―ノルステロイドの新誘導体、その製造方法、その薬剤としての使用及びそれを含有する製薬組成物 |
US4954490A (en) * | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
DE3822770A1 (de) * | 1988-07-01 | 1990-01-04 | Schering Ag | 13-alkyl-11ss-phenylgonane |
DE3832303A1 (de) * | 1988-09-20 | 1990-04-12 | Schering Ag | 11ss-phenyl-14ssh-steroide |
FR2643638B1 (fr) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
FR2644789B1 (fr) * | 1989-03-22 | 1995-02-03 | Roussel Uclaf | Nouveaux steroides 19-nor, 3-ceto comportant une chaine en 17 aminosubstituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
JP3135564B2 (ja) * | 1989-08-04 | 2001-02-19 | シエーリング アクチエンゲゼルシヤフト | 11β―置換16α,17α―メチレン―エストラ―4,9―ジエン―3―オン |
US5276023A (en) * | 1989-08-08 | 1994-01-04 | Roussel Uclaf | 19-nor-steroid esters |
FR2651435A1 (fr) * | 1989-09-07 | 1991-03-08 | Roussel Uclaf | Nouvelle utilisation de composes anti-progestomimetiques. |
US5407928A (en) * | 1990-08-15 | 1995-04-18 | Schering Aktiengesellschaft | 11β-aryl-gona-4,9-dien-3-ones |
DK0712311T3 (da) * | 1993-08-04 | 1999-06-21 | Akzo Nobel Nv | Antiglucocorticoidsteroider til behandling af angstlidelser |
-
1995
- 1995-05-16 EP EP95201268A patent/EP0683172B1/de not_active Expired - Lifetime
- 1995-05-16 CA CA002149496A patent/CA2149496C/en not_active Expired - Fee Related
- 1995-05-16 ES ES95201268T patent/ES2106616T3/es not_active Expired - Lifetime
- 1995-05-16 AT AT95201268T patent/ATE156836T1/de not_active IP Right Cessation
- 1995-05-16 DK DK95201268.0T patent/DK0683172T3/da active
- 1995-05-16 DE DE69500542T patent/DE69500542T2/de not_active Expired - Fee Related
- 1995-05-16 ZA ZA953976A patent/ZA953976B/xx unknown
- 1995-05-17 NZ NZ272143A patent/NZ272143A/en unknown
- 1995-05-18 JP JP12005195A patent/JP3814312B2/ja not_active Expired - Fee Related
- 1995-05-18 NO NO951968A patent/NO304379B1/no unknown
- 1995-05-18 PL PL95308666A patent/PL180481B1/pl not_active IP Right Cessation
- 1995-05-18 AU AU20133/95A patent/AU701616B2/en not_active Ceased
- 1995-05-18 BR BR9502085A patent/BR9502085A/pt not_active IP Right Cessation
- 1995-05-18 KR KR1019950012374A patent/KR100359474B1/ko not_active IP Right Cessation
- 1995-05-18 CN CN95105395A patent/CN1042539C/zh not_active Expired - Fee Related
- 1995-05-18 HU HU9501461A patent/HU217429B/hu not_active IP Right Cessation
- 1995-05-18 FI FI952424A patent/FI112491B/fi active
- 1995-05-18 RU RU95107892/04A patent/RU2152952C2/ru not_active IP Right Cessation
- 1995-05-19 US US08/445,119 patent/US5620966A/en not_active Expired - Fee Related
-
1997
- 1997-10-30 GR GR970402861T patent/GR3025225T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO951968L (no) | 1995-11-20 |
RU95107892A (ru) | 1997-02-10 |
PL308666A1 (en) | 1995-11-27 |
DK0683172T3 (da) | 1998-03-30 |
US5620966A (en) | 1997-04-15 |
CN1126727A (zh) | 1996-07-17 |
HU9501461D0 (en) | 1995-06-28 |
GR3025225T3 (en) | 1998-02-27 |
HU217429B (hu) | 2000-01-28 |
JPH07316187A (ja) | 1995-12-05 |
FI952424A (fi) | 1995-11-20 |
FI952424A0 (fi) | 1995-05-18 |
NO304379B1 (no) | 1998-12-07 |
DE69500542D1 (de) | 1997-09-18 |
EP0683172B1 (de) | 1997-08-13 |
EP0683172A1 (de) | 1995-11-22 |
ZA953976B (en) | 1996-01-19 |
AU2013395A (en) | 1995-11-30 |
NO951968D0 (no) | 1995-05-18 |
BR9502085A (pt) | 1996-03-05 |
DE69500542T2 (de) | 1998-01-02 |
HUT71804A (en) | 1996-02-28 |
AU701616B2 (en) | 1999-02-04 |
CA2149496A1 (en) | 1995-11-20 |
CN1042539C (zh) | 1999-03-17 |
JP3814312B2 (ja) | 2006-08-30 |
CA2149496C (en) | 2006-12-19 |
KR950032267A (ko) | 1995-12-20 |
KR100359474B1 (ko) | 2003-03-12 |
NZ272143A (en) | 1995-11-27 |
PL180481B1 (pl) | 2001-02-28 |
ES2106616T3 (es) | 1997-11-01 |
RU2152952C2 (ru) | 2000-07-20 |
FI112491B (fi) | 2003-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |