TR200003220T2 - İyi huylu prostat hiperplasianın tedavisinde yararlı olan yeni sübstitüe edilmiş piridino arilpiperazinler - Google Patents
İyi huylu prostat hiperplasianın tedavisinde yararlı olan yeni sübstitüe edilmiş piridino arilpiperazinlerInfo
- Publication number
- TR200003220T2 TR200003220T2 TR2000/03220T TR200003220T TR200003220T2 TR 200003220 T2 TR200003220 T2 TR 200003220T2 TR 2000/03220 T TR2000/03220 T TR 2000/03220T TR 200003220 T TR200003220 T TR 200003220T TR 200003220 T2 TR200003220 T2 TR 200003220T2
- Authority
- TR
- Turkey
- Prior art keywords
- treatment
- benign prostatic
- prostatic hyperplasia
- newly substituted
- substituted pyridino
- Prior art date
Links
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 title abstract 2
- 208000004403 Prostatic Hyperplasia Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102100024349 Alpha-1A adrenergic receptor Human genes 0.000 abstract 1
- 108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7532198P | 1998-02-20 | 1998-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200003220T2 true TR200003220T2 (tr) | 2001-04-20 |
Family
ID=22124955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/03220T TR200003220T2 (tr) | 1998-02-20 | 1999-02-19 | İyi huylu prostat hiperplasianın tedavisinde yararlı olan yeni sübstitüe edilmiş piridino arilpiperazinler |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6218396B1 (https=) |
| EP (1) | EP1054868B1 (https=) |
| JP (1) | JP2002503724A (https=) |
| KR (1) | KR100591028B1 (https=) |
| CN (1) | CN1121390C (https=) |
| AR (1) | AR014626A1 (https=) |
| AT (1) | ATE250580T1 (https=) |
| AU (1) | AU766398B2 (https=) |
| BR (1) | BR9909647A (https=) |
| CZ (1) | CZ294136B6 (https=) |
| DE (1) | DE69911582T2 (https=) |
| DK (1) | DK1054868T3 (https=) |
| ES (1) | ES2209468T3 (https=) |
| HU (1) | HUP0100781A3 (https=) |
| IL (2) | IL137954A0 (https=) |
| NO (1) | NO317103B1 (https=) |
| NZ (1) | NZ506462A (https=) |
| PL (1) | PL342339A1 (https=) |
| PT (1) | PT1054868E (https=) |
| TR (1) | TR200003220T2 (https=) |
| TW (1) | TW565555B (https=) |
| WO (1) | WO1999042448A1 (https=) |
| ZA (1) | ZA991315B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA001904B1 (ru) * | 1997-05-12 | 2001-10-22 | ОРТО МакНЕЙЛ ФАРМАСЬЮТИКАЛ, ИНК. | Арилзамещенные пиперазины для лечения доброкачественной гиперплазии простаты |
| CZ2003686A3 (cs) | 2000-08-08 | 2003-08-13 | Ortho Mcneil Pharmaceutical, Inc. | Neimidazolové aryloxypiperidiny |
| KR20060005009A (ko) | 2001-12-28 | 2006-01-16 | 다케다 야쿠힌 고교 가부시키가이샤 | 배뇨 장애 예방제/치료제 |
| USD545208S1 (en) | 2006-09-27 | 2007-06-26 | 001 Corporation | Perfume bottle and cap |
| EP2077262A4 (en) * | 2006-10-23 | 2011-12-28 | Takeda Pharmaceutical | IMINOPYRIDINE DERIVATIVE AND USE THEREOF |
| CL2009000964A1 (es) * | 2008-04-23 | 2010-03-26 | Takeda Pharmaceuticals Co | Compuestos derivados de 1-aril-2-imino-1,2-dihidropiridina-3-carboxamida, antagonista del receptor adrenergico alfa 1d, composicion farmaceutica que los comprende; y su uso para el tratamiento o profilaxis de enfermedades del tracto urinario inferior. |
| US20110039892A1 (en) * | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| US8481569B2 (en) * | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
| CN103980195A (zh) * | 2014-04-28 | 2014-08-13 | 广州医科大学 | 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用 |
| CN108530391B (zh) * | 2018-05-17 | 2022-05-17 | 袁牧 | 一种酰胺类芳基哌嗪衍生物及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
| US5403847A (en) | 1992-11-13 | 1995-04-04 | Synaptic Pharmaceutical Corporation | Use of α1C specific compounds to treat benign prostatic hyperlasia |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
| US5688795A (en) * | 1994-11-08 | 1997-11-18 | Syntex (U.S.A.) Inc. | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists |
| WO1999003833A1 (fr) * | 1997-07-15 | 1999-01-28 | Sankyo Company, Limited | Derives de piperazine |
-
1999
- 1999-02-18 US US09/252,313 patent/US6218396B1/en not_active Expired - Lifetime
- 1999-02-18 ZA ZA9901315A patent/ZA991315B/xx unknown
- 1999-02-19 CZ CZ20003044A patent/CZ294136B6/cs not_active IP Right Cessation
- 1999-02-19 TR TR2000/03220T patent/TR200003220T2/xx unknown
- 1999-02-19 HU HU0100781A patent/HUP0100781A3/hu unknown
- 1999-02-19 BR BR9909647-1A patent/BR9909647A/pt not_active Application Discontinuation
- 1999-02-19 DE DE69911582T patent/DE69911582T2/de not_active Expired - Fee Related
- 1999-02-19 DK DK99934281T patent/DK1054868T3/da active
- 1999-02-19 ES ES99934281T patent/ES2209468T3/es not_active Expired - Lifetime
- 1999-02-19 IL IL13795499A patent/IL137954A0/xx active IP Right Grant
- 1999-02-19 KR KR1020007009156A patent/KR100591028B1/ko not_active Expired - Fee Related
- 1999-02-19 JP JP2000532400A patent/JP2002503724A/ja active Pending
- 1999-02-19 PT PT99934281T patent/PT1054868E/pt unknown
- 1999-02-19 PL PL99342339A patent/PL342339A1/xx unknown
- 1999-02-19 AT AT99934281T patent/ATE250580T1/de not_active IP Right Cessation
- 1999-02-19 EP EP99934281A patent/EP1054868B1/en not_active Expired - Lifetime
- 1999-02-19 CN CN99803027A patent/CN1121390C/zh not_active Expired - Fee Related
- 1999-02-19 WO PCT/US1999/003608 patent/WO1999042448A1/en not_active Ceased
- 1999-02-19 NZ NZ506462A patent/NZ506462A/en unknown
- 1999-02-19 AU AU33025/99A patent/AU766398B2/en not_active Ceased
- 1999-02-23 AR ARP990100675A patent/AR014626A1/es active IP Right Grant
- 1999-04-02 TW TW088102511A patent/TW565555B/zh not_active IP Right Cessation
-
2000
- 2000-08-18 IL IL137954A patent/IL137954A/en not_active IP Right Cessation
- 2000-08-18 NO NO20004141A patent/NO317103B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1030776A1 (en) | 2001-05-18 |
| DE69911582D1 (de) | 2003-10-30 |
| BR9909647A (pt) | 2000-11-21 |
| IL137954A (en) | 2007-06-03 |
| EP1054868A1 (en) | 2000-11-29 |
| AU3302599A (en) | 1999-09-06 |
| CN1291188A (zh) | 2001-04-11 |
| ES2209468T3 (es) | 2004-06-16 |
| NZ506462A (en) | 2003-07-25 |
| ZA991315B (en) | 2000-11-20 |
| NO20004141L (no) | 2000-10-19 |
| IL137954A0 (en) | 2001-10-31 |
| DE69911582T2 (de) | 2005-09-15 |
| EP1054868B1 (en) | 2003-09-24 |
| CZ294136B6 (cs) | 2004-10-13 |
| KR20010041115A (ko) | 2001-05-15 |
| DK1054868T3 (da) | 2003-12-22 |
| US6218396B1 (en) | 2001-04-17 |
| WO1999042448A1 (en) | 1999-08-26 |
| HUP0100781A3 (en) | 2002-12-28 |
| ATE250580T1 (de) | 2003-10-15 |
| AU766398B2 (en) | 2003-10-16 |
| HUP0100781A2 (hu) | 2001-08-28 |
| PL342339A1 (en) | 2001-06-04 |
| PT1054868E (pt) | 2004-01-30 |
| CN1121390C (zh) | 2003-09-17 |
| NO317103B1 (no) | 2004-08-09 |
| AR014626A1 (es) | 2001-03-28 |
| TW565555B (en) | 2003-12-11 |
| KR100591028B1 (ko) | 2006-06-22 |
| CZ20003044A3 (cs) | 2001-04-11 |
| NO20004141D0 (no) | 2000-08-18 |
| JP2002503724A (ja) | 2002-02-05 |
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