BR9909647A - Compostos de piridino arilpiperazinas substituìdos, de utilidade no tratamento de hiperplasia prostática benigna - Google Patents
Compostos de piridino arilpiperazinas substituìdos, de utilidade no tratamento de hiperplasia prostática benignaInfo
- Publication number
- BR9909647A BR9909647A BR9909647-1A BR9909647A BR9909647A BR 9909647 A BR9909647 A BR 9909647A BR 9909647 A BR9909647 A BR 9909647A BR 9909647 A BR9909647 A BR 9909647A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- benign prostatic
- prostatic hyperplasia
- compounds
- substituted
- Prior art date
Links
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 title abstract 3
- 208000004403 Prostatic Hyperplasia Diseases 0.000 title abstract 3
- 150000003222 pyridines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 108060003345 Adrenergic Receptor Proteins 0.000 abstract 1
- 102000017910 Adrenergic receptor Human genes 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 230000001010 compromised effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- -1 heterocyclic piperazines Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7532198P | 1998-02-20 | 1998-02-20 | |
| PCT/US1999/003608 WO1999042448A1 (en) | 1998-02-20 | 1999-02-19 | Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9909647A true BR9909647A (pt) | 2000-11-21 |
Family
ID=22124955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9909647-1A BR9909647A (pt) | 1998-02-20 | 1999-02-19 | Compostos de piridino arilpiperazinas substituìdos, de utilidade no tratamento de hiperplasia prostática benigna |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6218396B1 (https=) |
| EP (1) | EP1054868B1 (https=) |
| JP (1) | JP2002503724A (https=) |
| KR (1) | KR100591028B1 (https=) |
| CN (1) | CN1121390C (https=) |
| AR (1) | AR014626A1 (https=) |
| AT (1) | ATE250580T1 (https=) |
| AU (1) | AU766398B2 (https=) |
| BR (1) | BR9909647A (https=) |
| CZ (1) | CZ294136B6 (https=) |
| DE (1) | DE69911582T2 (https=) |
| DK (1) | DK1054868T3 (https=) |
| ES (1) | ES2209468T3 (https=) |
| HU (1) | HUP0100781A3 (https=) |
| IL (2) | IL137954A0 (https=) |
| NO (1) | NO317103B1 (https=) |
| NZ (1) | NZ506462A (https=) |
| PL (1) | PL342339A1 (https=) |
| PT (1) | PT1054868E (https=) |
| TR (1) | TR200003220T2 (https=) |
| TW (1) | TW565555B (https=) |
| WO (1) | WO1999042448A1 (https=) |
| ZA (1) | ZA991315B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA001904B1 (ru) * | 1997-05-12 | 2001-10-22 | ОРТО МакНЕЙЛ ФАРМАСЬЮТИКАЛ, ИНК. | Арилзамещенные пиперазины для лечения доброкачественной гиперплазии простаты |
| CZ2003686A3 (cs) | 2000-08-08 | 2003-08-13 | Ortho Mcneil Pharmaceutical, Inc. | Neimidazolové aryloxypiperidiny |
| KR20060005009A (ko) | 2001-12-28 | 2006-01-16 | 다케다 야쿠힌 고교 가부시키가이샤 | 배뇨 장애 예방제/치료제 |
| USD545208S1 (en) | 2006-09-27 | 2007-06-26 | 001 Corporation | Perfume bottle and cap |
| EP2077262A4 (en) * | 2006-10-23 | 2011-12-28 | Takeda Pharmaceutical | IMINOPYRIDINE DERIVATIVE AND USE THEREOF |
| CL2009000964A1 (es) * | 2008-04-23 | 2010-03-26 | Takeda Pharmaceuticals Co | Compuestos derivados de 1-aril-2-imino-1,2-dihidropiridina-3-carboxamida, antagonista del receptor adrenergico alfa 1d, composicion farmaceutica que los comprende; y su uso para el tratamiento o profilaxis de enfermedades del tracto urinario inferior. |
| US20110039892A1 (en) * | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| US8481569B2 (en) * | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
| CN103980195A (zh) * | 2014-04-28 | 2014-08-13 | 广州医科大学 | 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用 |
| CN108530391B (zh) * | 2018-05-17 | 2022-05-17 | 袁牧 | 一种酰胺类芳基哌嗪衍生物及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
| US5403847A (en) | 1992-11-13 | 1995-04-04 | Synaptic Pharmaceutical Corporation | Use of α1C specific compounds to treat benign prostatic hyperlasia |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
| US5688795A (en) * | 1994-11-08 | 1997-11-18 | Syntex (U.S.A.) Inc. | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists |
| WO1999003833A1 (fr) * | 1997-07-15 | 1999-01-28 | Sankyo Company, Limited | Derives de piperazine |
-
1999
- 1999-02-18 US US09/252,313 patent/US6218396B1/en not_active Expired - Lifetime
- 1999-02-18 ZA ZA9901315A patent/ZA991315B/xx unknown
- 1999-02-19 CZ CZ20003044A patent/CZ294136B6/cs not_active IP Right Cessation
- 1999-02-19 TR TR2000/03220T patent/TR200003220T2/xx unknown
- 1999-02-19 HU HU0100781A patent/HUP0100781A3/hu unknown
- 1999-02-19 BR BR9909647-1A patent/BR9909647A/pt not_active Application Discontinuation
- 1999-02-19 DE DE69911582T patent/DE69911582T2/de not_active Expired - Fee Related
- 1999-02-19 DK DK99934281T patent/DK1054868T3/da active
- 1999-02-19 ES ES99934281T patent/ES2209468T3/es not_active Expired - Lifetime
- 1999-02-19 IL IL13795499A patent/IL137954A0/xx active IP Right Grant
- 1999-02-19 KR KR1020007009156A patent/KR100591028B1/ko not_active Expired - Fee Related
- 1999-02-19 JP JP2000532400A patent/JP2002503724A/ja active Pending
- 1999-02-19 PT PT99934281T patent/PT1054868E/pt unknown
- 1999-02-19 PL PL99342339A patent/PL342339A1/xx unknown
- 1999-02-19 AT AT99934281T patent/ATE250580T1/de not_active IP Right Cessation
- 1999-02-19 EP EP99934281A patent/EP1054868B1/en not_active Expired - Lifetime
- 1999-02-19 CN CN99803027A patent/CN1121390C/zh not_active Expired - Fee Related
- 1999-02-19 WO PCT/US1999/003608 patent/WO1999042448A1/en not_active Ceased
- 1999-02-19 NZ NZ506462A patent/NZ506462A/en unknown
- 1999-02-19 AU AU33025/99A patent/AU766398B2/en not_active Ceased
- 1999-02-23 AR ARP990100675A patent/AR014626A1/es active IP Right Grant
- 1999-04-02 TW TW088102511A patent/TW565555B/zh not_active IP Right Cessation
-
2000
- 2000-08-18 IL IL137954A patent/IL137954A/en not_active IP Right Cessation
- 2000-08-18 NO NO20004141A patent/NO317103B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1030776A1 (en) | 2001-05-18 |
| DE69911582D1 (de) | 2003-10-30 |
| IL137954A (en) | 2007-06-03 |
| EP1054868A1 (en) | 2000-11-29 |
| AU3302599A (en) | 1999-09-06 |
| CN1291188A (zh) | 2001-04-11 |
| ES2209468T3 (es) | 2004-06-16 |
| NZ506462A (en) | 2003-07-25 |
| ZA991315B (en) | 2000-11-20 |
| NO20004141L (no) | 2000-10-19 |
| IL137954A0 (en) | 2001-10-31 |
| DE69911582T2 (de) | 2005-09-15 |
| EP1054868B1 (en) | 2003-09-24 |
| CZ294136B6 (cs) | 2004-10-13 |
| KR20010041115A (ko) | 2001-05-15 |
| DK1054868T3 (da) | 2003-12-22 |
| US6218396B1 (en) | 2001-04-17 |
| WO1999042448A1 (en) | 1999-08-26 |
| HUP0100781A3 (en) | 2002-12-28 |
| ATE250580T1 (de) | 2003-10-15 |
| AU766398B2 (en) | 2003-10-16 |
| HUP0100781A2 (hu) | 2001-08-28 |
| PL342339A1 (en) | 2001-06-04 |
| PT1054868E (pt) | 2004-01-30 |
| CN1121390C (zh) | 2003-09-17 |
| NO317103B1 (no) | 2004-08-09 |
| TR200003220T2 (tr) | 2001-04-20 |
| AR014626A1 (es) | 2001-03-28 |
| TW565555B (en) | 2003-12-11 |
| KR100591028B1 (ko) | 2006-06-22 |
| CZ20003044A3 (cs) | 2001-04-11 |
| NO20004141D0 (no) | 2000-08-18 |
| JP2002503724A (ja) | 2002-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9510104A (pt) | Novas sulfonamidas | |
| HUT77925A (hu) | Dihidrobenzofuránok, azokat tartalmazó gyógyászati készítmények és eljárás előállításukra | |
| NO20015226L (no) | Tri-aryl syrederivater som PPAR reseptor ligander, farmasoytisk sammensetning omfattende samme og anvendelse av samme for fremstilling av medikament. | |
| TR200001973T2 (tr) | 11 ß-halojen-7alfa-ile ikame edilmiş-estratrienler, bu 11ß-halojen-7alfa-ile ikame edilmiş-estratrienleri içeren farmasötik terkiplerin üretimi için yöntem ve ilaç üretiminde kullanımları. | |
| NO20022857L (no) | Nye P2X7-reseptoragonister for bruk i behandling av inflammatoriske, immun- eller kardiovaskul¶re sykdommer | |
| BR0111596A (pt) | Composto e seu uso, processo para sua produção, composição farmacêutica e processo e método para prevenir ou tratar doenças | |
| AR014261A1 (es) | Compuestos hipolipidemicos de benzotiazepina, composiciones y proceso para su preparacion | |
| ATE193883T1 (de) | Verbindungen und ihre zusammensetzungen mit entzündungshemmenden und anti-thrombotischen wirkungen | |
| IS6658A (is) | Ný efnasambönd | |
| ATE344033T1 (de) | Vinylphenyl-derivate als glk-aktivatoren | |
| PT1263725E (pt) | Novos compostos | |
| DE69922703D1 (de) | Ureido-thiobuttersäurederivate als ppar-agonisten | |
| ATE416157T1 (de) | Inhibitoren von integrin alpha-v-beta-6 | |
| HRP20050830A2 (en) | Non-nucleoside reverse transcriptase inhibitors i for treating hiv mediated diseases | |
| TR200201168T2 (tr) | CGRP-Antagonistleri-yeni siklopropanlar içeren ilaçlar ve üretim yöntemleri. | |
| BR9909647A (pt) | Compostos de piridino arilpiperazinas substituìdos, de utilidade no tratamento de hiperplasia prostática benigna | |
| NO306345B1 (no) | Piperidin-derivater med PAF antagonist-aktivitet, anvendelse derav og farmasöytisk blanding | |
| FI973221A0 (fi) | 1-aryyli-2-asyyliammo-etaaniyhdisteitä ja niiden käyttö neurokiniiniantagonisteina, erityisesti neurokiniini 1 antagonisteina | |
| TR200100895T2 (tr) | Heterosiklik ikameli propanolamin türevleri, üretimi, ilaçları,kullanımı | |
| SE0003476D0 (sv) | Compounds | |
| BR0309014A (pt) | ácido(2-((2-alcóxi)-fenil)-ciclopent-1-enil)carbo e heterocìclico aromático e derivados | |
| SE9904128D0 (sv) | Novel compounds | |
| ATE293591T1 (de) | Neue n-(2-phenyl-3-aminopropyl)naphtamide | |
| BR0212451A (pt) | Antagonistas de receptores de ccr-3 v | |
| NO954316D0 (no) | Benzo(f)kinoksalidinonderivater, deres fremstilling og anvendelse i legemidler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AOS REQUISITOS DOS ARTIGOS 8 E 13 DA LPI. |