PT1054868E - Novas piridino arilpiperazinas substitidas uteis no tratamento de hiperplasia prostatica benigna - Google Patents
Novas piridino arilpiperazinas substitidas uteis no tratamento de hiperplasia prostatica benignaInfo
- Publication number
- PT1054868E PT1054868E PT99934281T PT99934281T PT1054868E PT 1054868 E PT1054868 E PT 1054868E PT 99934281 T PT99934281 T PT 99934281T PT 99934281 T PT99934281 T PT 99934281T PT 1054868 E PT1054868 E PT 1054868E
- Authority
- PT
- Portugal
- Prior art keywords
- arilpiperazines
- treatment
- benign prostatic
- prostatic hyperplasia
- new pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7532198P | 1998-02-20 | 1998-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1054868E true PT1054868E (pt) | 2004-01-30 |
Family
ID=22124955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99934281T PT1054868E (pt) | 1998-02-20 | 1999-02-19 | Novas piridino arilpiperazinas substitidas uteis no tratamento de hiperplasia prostatica benigna |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6218396B1 (pt) |
| EP (1) | EP1054868B1 (pt) |
| JP (1) | JP2002503724A (pt) |
| KR (1) | KR100591028B1 (pt) |
| CN (1) | CN1121390C (pt) |
| AR (1) | AR014626A1 (pt) |
| AT (1) | ATE250580T1 (pt) |
| AU (1) | AU766398B2 (pt) |
| BR (1) | BR9909647A (pt) |
| CZ (1) | CZ294136B6 (pt) |
| DE (1) | DE69911582T2 (pt) |
| DK (1) | DK1054868T3 (pt) |
| ES (1) | ES2209468T3 (pt) |
| HK (1) | HK1030776A1 (pt) |
| HU (1) | HUP0100781A3 (pt) |
| IL (2) | IL137954A0 (pt) |
| NO (1) | NO317103B1 (pt) |
| NZ (1) | NZ506462A (pt) |
| PL (1) | PL342339A1 (pt) |
| PT (1) | PT1054868E (pt) |
| TR (1) | TR200003220T2 (pt) |
| TW (1) | TW565555B (pt) |
| WO (1) | WO1999042448A1 (pt) |
| ZA (1) | ZA991315B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA001904B1 (ru) * | 1997-05-12 | 2001-10-22 | ОРТО МакНЕЙЛ ФАРМАСЬЮТИКАЛ, ИНК. | Арилзамещенные пиперазины для лечения доброкачественной гиперплазии простаты |
| AU8112101A (en) | 2000-08-08 | 2002-02-18 | Ortho Mcneil Pharm Inc | Non-imidazole aryloxypiperidines |
| NZ533774A (en) * | 2001-12-28 | 2006-08-31 | Takeda Pharmaceutical | Preventatives/remedies for urinary disturbance |
| JP5483880B2 (ja) * | 2006-10-23 | 2014-05-07 | 武田薬品工業株式会社 | イミノピリジン誘導体およびその用途 |
| US20110039846A1 (en) * | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
| US20110039892A1 (en) * | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| US8481569B2 (en) | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
| CN103980195A (zh) * | 2014-04-28 | 2014-08-13 | 广州医科大学 | 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用 |
| CN108530391B (zh) * | 2018-05-17 | 2022-05-17 | 袁牧 | 一种酰胺类芳基哌嗪衍生物及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
| US5403847A (en) | 1992-11-13 | 1995-04-04 | Synaptic Pharmaceutical Corporation | Use of α1C specific compounds to treat benign prostatic hyperlasia |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
| US5688795A (en) | 1994-11-08 | 1997-11-18 | Syntex (U.S.A.) Inc. | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists |
| WO1999003833A1 (en) * | 1997-07-15 | 1999-01-28 | Sankyo Company, Limited | Piperazine derivatives |
-
1999
- 1999-02-18 ZA ZA9901315A patent/ZA991315B/xx unknown
- 1999-02-18 US US09/252,313 patent/US6218396B1/en not_active Expired - Lifetime
- 1999-02-19 EP EP99934281A patent/EP1054868B1/en not_active Expired - Lifetime
- 1999-02-19 DK DK99934281T patent/DK1054868T3/da active
- 1999-02-19 ES ES99934281T patent/ES2209468T3/es not_active Expired - Lifetime
- 1999-02-19 AT AT99934281T patent/ATE250580T1/de not_active IP Right Cessation
- 1999-02-19 HU HU0100781A patent/HUP0100781A3/hu unknown
- 1999-02-19 DE DE69911582T patent/DE69911582T2/de not_active Expired - Fee Related
- 1999-02-19 NZ NZ506462A patent/NZ506462A/en unknown
- 1999-02-19 AU AU33025/99A patent/AU766398B2/en not_active Ceased
- 1999-02-19 WO PCT/US1999/003608 patent/WO1999042448A1/en active IP Right Grant
- 1999-02-19 IL IL13795499A patent/IL137954A0/xx active IP Right Grant
- 1999-02-19 BR BR9909647-1A patent/BR9909647A/pt not_active Application Discontinuation
- 1999-02-19 KR KR1020007009156A patent/KR100591028B1/ko not_active IP Right Cessation
- 1999-02-19 TR TR2000/03220T patent/TR200003220T2/xx unknown
- 1999-02-19 PL PL99342339A patent/PL342339A1/xx unknown
- 1999-02-19 PT PT99934281T patent/PT1054868E/pt unknown
- 1999-02-19 CZ CZ20003044A patent/CZ294136B6/cs not_active IP Right Cessation
- 1999-02-19 CN CN99803027A patent/CN1121390C/zh not_active Expired - Fee Related
- 1999-02-19 JP JP2000532400A patent/JP2002503724A/ja active Pending
- 1999-02-23 AR ARP990100675A patent/AR014626A1/es active IP Right Grant
- 1999-04-02 TW TW088102511A patent/TW565555B/zh not_active IP Right Cessation
-
2000
- 2000-08-18 NO NO20004141A patent/NO317103B1/no not_active IP Right Cessation
- 2000-08-18 IL IL137954A patent/IL137954A/en not_active IP Right Cessation
-
2001
- 2001-03-08 HK HK01101679A patent/HK1030776A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010041115A (ko) | 2001-05-15 |
| EP1054868A1 (en) | 2000-11-29 |
| AU3302599A (en) | 1999-09-06 |
| CZ294136B6 (cs) | 2004-10-13 |
| IL137954A (en) | 2007-06-03 |
| JP2002503724A (ja) | 2002-02-05 |
| TR200003220T2 (tr) | 2001-04-20 |
| PL342339A1 (en) | 2001-06-04 |
| IL137954A0 (en) | 2001-10-31 |
| TW565555B (en) | 2003-12-11 |
| CZ20003044A3 (cs) | 2001-04-11 |
| AU766398B2 (en) | 2003-10-16 |
| HUP0100781A3 (en) | 2002-12-28 |
| NO20004141L (no) | 2000-10-19 |
| DE69911582D1 (de) | 2003-10-30 |
| US6218396B1 (en) | 2001-04-17 |
| CN1121390C (zh) | 2003-09-17 |
| DK1054868T3 (da) | 2003-12-22 |
| HK1030776A1 (en) | 2001-05-18 |
| WO1999042448A1 (en) | 1999-08-26 |
| ATE250580T1 (de) | 2003-10-15 |
| NO20004141D0 (no) | 2000-08-18 |
| EP1054868B1 (en) | 2003-09-24 |
| CN1291188A (zh) | 2001-04-11 |
| BR9909647A (pt) | 2000-11-21 |
| AR014626A1 (es) | 2001-03-28 |
| DE69911582T2 (de) | 2005-09-15 |
| ZA991315B (en) | 2000-11-20 |
| KR100591028B1 (ko) | 2006-06-22 |
| HUP0100781A2 (hu) | 2001-08-28 |
| NZ506462A (en) | 2003-07-25 |
| ES2209468T3 (es) | 2004-06-16 |
| NO317103B1 (no) | 2004-08-09 |
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