ATE250580T1 - Substituierte pyridino-arylpiperazine zur behandlung benigner prostatahyperplasie - Google Patents
Substituierte pyridino-arylpiperazine zur behandlung benigner prostatahyperplasieInfo
- Publication number
- ATE250580T1 ATE250580T1 AT99934281T AT99934281T ATE250580T1 AT E250580 T1 ATE250580 T1 AT E250580T1 AT 99934281 T AT99934281 T AT 99934281T AT 99934281 T AT99934281 T AT 99934281T AT E250580 T1 ATE250580 T1 AT E250580T1
- Authority
- AT
- Austria
- Prior art keywords
- benigger
- arylpiperazine
- treatment
- prostate hyperplasia
- substituted pyridino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7532198P | 1998-02-20 | 1998-02-20 | |
| PCT/US1999/003608 WO1999042448A1 (en) | 1998-02-20 | 1999-02-19 | Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE250580T1 true ATE250580T1 (de) | 2003-10-15 |
Family
ID=22124955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99934281T ATE250580T1 (de) | 1998-02-20 | 1999-02-19 | Substituierte pyridino-arylpiperazine zur behandlung benigner prostatahyperplasie |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6218396B1 (de) |
| EP (1) | EP1054868B1 (de) |
| JP (1) | JP2002503724A (de) |
| KR (1) | KR100591028B1 (de) |
| CN (1) | CN1121390C (de) |
| AR (1) | AR014626A1 (de) |
| AT (1) | ATE250580T1 (de) |
| AU (1) | AU766398B2 (de) |
| BR (1) | BR9909647A (de) |
| CZ (1) | CZ294136B6 (de) |
| DE (1) | DE69911582T2 (de) |
| DK (1) | DK1054868T3 (de) |
| ES (1) | ES2209468T3 (de) |
| HK (1) | HK1030776A1 (de) |
| HU (1) | HUP0100781A3 (de) |
| IL (2) | IL137954A0 (de) |
| NO (1) | NO317103B1 (de) |
| NZ (1) | NZ506462A (de) |
| PL (1) | PL342339A1 (de) |
| PT (1) | PT1054868E (de) |
| TR (1) | TR200003220T2 (de) |
| TW (1) | TW565555B (de) |
| WO (1) | WO1999042448A1 (de) |
| ZA (1) | ZA991315B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1515556A (zh) * | 1997-05-12 | 2004-07-28 | ����-������ҩƷ��˾ | 用以制备芳基取代哌嗪的中间体化合物 |
| WO2002012190A2 (en) | 2000-08-08 | 2002-02-14 | Ortho Mcneil Pharmaceutical, Inc. | Non-imidazole aryloxypiperidines as h3 receptor ligands |
| MXPA04006344A (es) * | 2001-12-28 | 2005-03-31 | Takeda Pharmaceutical | Preventivos/remedios para la perturbacion de miccion. |
| WO2008050732A1 (fr) * | 2006-10-23 | 2008-05-02 | Takeda Pharmaceutical Company Limited | Dérivé de l'iminopyridine et son utilisation |
| UY31781A (es) * | 2008-04-23 | 2009-12-14 | Takeda Pharmaceutical | Derivados de iminopiridina y su uso |
| US20110039892A1 (en) * | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| US8481569B2 (en) | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
| CN103980195A (zh) * | 2014-04-28 | 2014-08-13 | 广州医科大学 | 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用 |
| CN108530391B (zh) * | 2018-05-17 | 2022-05-17 | 袁牧 | 一种酰胺类芳基哌嗪衍生物及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
| US5403847A (en) | 1992-11-13 | 1995-04-04 | Synaptic Pharmaceutical Corporation | Use of α1C specific compounds to treat benign prostatic hyperlasia |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
| US5688795A (en) * | 1994-11-08 | 1997-11-18 | Syntex (U.S.A.) Inc. | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists |
| WO1999003833A1 (en) * | 1997-07-15 | 1999-01-28 | Sankyo Company, Limited | Piperazine derivatives |
-
1999
- 1999-02-18 US US09/252,313 patent/US6218396B1/en not_active Expired - Lifetime
- 1999-02-18 ZA ZA9901315A patent/ZA991315B/xx unknown
- 1999-02-19 AU AU33025/99A patent/AU766398B2/en not_active Ceased
- 1999-02-19 NZ NZ506462A patent/NZ506462A/en unknown
- 1999-02-19 KR KR1020007009156A patent/KR100591028B1/ko not_active IP Right Cessation
- 1999-02-19 HU HU0100781A patent/HUP0100781A3/hu unknown
- 1999-02-19 EP EP99934281A patent/EP1054868B1/de not_active Expired - Lifetime
- 1999-02-19 ES ES99934281T patent/ES2209468T3/es not_active Expired - Lifetime
- 1999-02-19 IL IL13795499A patent/IL137954A0/xx active IP Right Grant
- 1999-02-19 JP JP2000532400A patent/JP2002503724A/ja active Pending
- 1999-02-19 DK DK99934281T patent/DK1054868T3/da active
- 1999-02-19 WO PCT/US1999/003608 patent/WO1999042448A1/en active IP Right Grant
- 1999-02-19 PT PT99934281T patent/PT1054868E/pt unknown
- 1999-02-19 DE DE69911582T patent/DE69911582T2/de not_active Expired - Fee Related
- 1999-02-19 TR TR2000/03220T patent/TR200003220T2/xx unknown
- 1999-02-19 BR BR9909647-1A patent/BR9909647A/pt not_active Application Discontinuation
- 1999-02-19 CZ CZ20003044A patent/CZ294136B6/cs not_active IP Right Cessation
- 1999-02-19 CN CN99803027A patent/CN1121390C/zh not_active Expired - Fee Related
- 1999-02-19 PL PL99342339A patent/PL342339A1/xx unknown
- 1999-02-19 AT AT99934281T patent/ATE250580T1/de not_active IP Right Cessation
- 1999-02-23 AR ARP990100675A patent/AR014626A1/es active IP Right Grant
- 1999-04-02 TW TW088102511A patent/TW565555B/zh not_active IP Right Cessation
-
2000
- 2000-08-18 IL IL137954A patent/IL137954A/en not_active IP Right Cessation
- 2000-08-18 NO NO20004141A patent/NO317103B1/no not_active IP Right Cessation
-
2001
- 2001-03-08 HK HK01101679A patent/HK1030776A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1054868A1 (de) | 2000-11-29 |
| BR9909647A (pt) | 2000-11-21 |
| ZA991315B (en) | 2000-11-20 |
| CZ20003044A3 (cs) | 2001-04-11 |
| TW565555B (en) | 2003-12-11 |
| NO317103B1 (no) | 2004-08-09 |
| IL137954A (en) | 2007-06-03 |
| AU766398B2 (en) | 2003-10-16 |
| EP1054868B1 (de) | 2003-09-24 |
| DE69911582D1 (de) | 2003-10-30 |
| AU3302599A (en) | 1999-09-06 |
| DE69911582T2 (de) | 2005-09-15 |
| HUP0100781A2 (hu) | 2001-08-28 |
| KR20010041115A (ko) | 2001-05-15 |
| PL342339A1 (en) | 2001-06-04 |
| HUP0100781A3 (en) | 2002-12-28 |
| KR100591028B1 (ko) | 2006-06-22 |
| NZ506462A (en) | 2003-07-25 |
| NO20004141L (no) | 2000-10-19 |
| HK1030776A1 (en) | 2001-05-18 |
| NO20004141D0 (no) | 2000-08-18 |
| JP2002503724A (ja) | 2002-02-05 |
| CZ294136B6 (cs) | 2004-10-13 |
| WO1999042448A1 (en) | 1999-08-26 |
| AR014626A1 (es) | 2001-03-28 |
| IL137954A0 (en) | 2001-10-31 |
| CN1121390C (zh) | 2003-09-17 |
| DK1054868T3 (da) | 2003-12-22 |
| US6218396B1 (en) | 2001-04-17 |
| PT1054868E (pt) | 2004-01-30 |
| TR200003220T2 (tr) | 2001-04-20 |
| CN1291188A (zh) | 2001-04-11 |
| ES2209468T3 (es) | 2004-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1054868 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |