TR200001340A2 - Nükleosit analogların sentezi için proses - Google Patents

Nükleosit analogların sentezi için proses

Info

Publication number
TR200001340A2
TR200001340A2 TR2000/01340A TR200001340A TR200001340A2 TR 200001340 A2 TR200001340 A2 TR 200001340A2 TR 2000/01340 A TR2000/01340 A TR 2000/01340A TR 200001340 A TR200001340 A TR 200001340A TR 200001340 A2 TR200001340 A2 TR 200001340A2
Authority
TR
Turkey
Prior art keywords
synthesis
nucleoside analogs
protected
nucleosides
coupling
Prior art date
Application number
TR2000/01340A
Other languages
English (en)
Inventor
W�Ll�Am Scott Robert
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200001340A2 publication Critical patent/TR200001340A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Elimizdeki bulus düsük alfa:beta anomerik oranli nükleositlerin sentezi için gelistirilmis bir yöntemle ilgilidir. Yöntem, korunmus bir furanosil halojenürün, bir nükleofilik poler eritken ile kuvetli bir baz varliginda, uygun sekilde korunmus bir heterosikl ile çiftlenmesinden olusur.
TR2000/01340A 1999-05-11 2000-05-11 Nükleosit analogların sentezi için proses TR200001340A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13365199P 1999-05-11 1999-05-11

Publications (1)

Publication Number Publication Date
TR200001340A2 true TR200001340A2 (tr) 2000-12-21

Family

ID=22459680

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01340A TR200001340A2 (tr) 1999-05-11 2000-05-11 Nükleosit analogların sentezi için proses

Country Status (22)

Country Link
US (1) US6271370B1 (tr)
EP (1) EP1052264B1 (tr)
JP (1) JP2001011092A (tr)
KR (1) KR100403900B1 (tr)
CN (1) CN1275575A (tr)
AR (1) AR028991A1 (tr)
AT (1) ATE291582T1 (tr)
AU (1) AU3401100A (tr)
BR (1) BR0002089A (tr)
CA (1) CA2307951A1 (tr)
CZ (1) CZ20001710A3 (tr)
DE (1) DE60018833D1 (tr)
HU (1) HUP0001843A3 (tr)
ID (1) ID25992A (tr)
IL (1) IL136027A0 (tr)
IN (1) IN186850B (tr)
MX (1) MXPA00004532A (tr)
PL (1) PL340109A1 (tr)
RU (1) RU2200738C2 (tr)
TR (1) TR200001340A2 (tr)
YU (1) YU25500A (tr)
ZA (1) ZA200002263B (tr)

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Also Published As

Publication number Publication date
CA2307951A1 (en) 2000-11-11
HU0001843D0 (en) 2000-07-28
BR0002089A (pt) 2001-01-02
HUP0001843A2 (hu) 2001-06-28
RU2200738C2 (ru) 2003-03-20
IN186850B (tr) 2001-11-24
CZ20001710A3 (cs) 2001-09-12
HUP0001843A3 (en) 2001-09-28
ZA200002263B (en) 2001-12-24
AR028991A1 (es) 2003-06-04
DE60018833D1 (de) 2005-04-28
US6271370B1 (en) 2001-08-07
KR20010069193A (ko) 2001-07-23
EP1052264A3 (en) 2001-06-13
JP2001011092A (ja) 2001-01-16
EP1052264A2 (en) 2000-11-15
ID25992A (id) 2000-11-16
EP1052264B1 (en) 2005-03-23
CN1275575A (zh) 2000-12-06
YU25500A (sh) 2003-08-29
KR100403900B1 (ko) 2003-11-01
AU3401100A (en) 2000-11-16
IL136027A0 (en) 2001-05-20
PL340109A1 (en) 2000-11-20
ATE291582T1 (de) 2005-04-15
MXPA00004532A (es) 2002-03-08

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