TR199901394T2 - NMDA antagonistleri hazirlanmasi için islem - Google Patents

NMDA antagonistleri hazirlanmasi için islem

Info

Publication number
TR199901394T2
TR199901394T2 TR1999/01394T TR9901394T TR199901394T2 TR 199901394 T2 TR199901394 T2 TR 199901394T2 TR 1999/01394 T TR1999/01394 T TR 1999/01394T TR 9901394 T TR9901394 T TR 9901394T TR 199901394 T2 TR199901394 T2 TR 199901394T2
Authority
TR
Turkey
Prior art keywords
formula
preparation
nmda antagonists
alkyl
followed
Prior art date
Application number
TR1999/01394T
Other languages
English (en)
Inventor
Richard Harris Alan
Original Assignee
Astra Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceuticals Ltd. filed Critical Astra Pharmaceuticals Ltd.
Publication of TR199901394T2 publication Critical patent/TR199901394T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Bu bulus ilaç olarak yararli olan formül (I)'in bilinen amin bilesimlerinin üretimi için gelistirilmis bir islem ile ilgilidir; burada R1 ve R2 bagimsiz olarak fenil ya da 4-florofenildir; R3 hidrojen, alkil C1-4 ya da metoksikarbonildir; R4 hidrojen ya da metildir; islem formül (II)'nin bir bilesiminin R5, R6, R7, R8, R9 ve R10'un bagimsiz olarak C1-6 alkil oldugu formül (III)'nin bir bilesimi ile, reaksiyonu ve onu takiben korumanin kaldirilmasi ve istege bagli olarak daha sonra farmasötik olarak uygun bir tuzun olusturulmasini içerir.
TR1999/01394T 1996-12-19 1997-12-12 NMDA antagonistleri hazirlanmasi için islem TR199901394T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9626319.9A GB9626319D0 (en) 1996-12-19 1996-12-19 Synthetic method

Publications (1)

Publication Number Publication Date
TR199901394T2 true TR199901394T2 (tr) 1999-08-23

Family

ID=10804657

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/01394T TR199901394T2 (tr) 1996-12-19 1997-12-12 NMDA antagonistleri hazirlanmasi için islem

Country Status (33)

Country Link
US (1) US6063962A (tr)
EP (1) EP0946497B1 (tr)
JP (1) JP2002512595A (tr)
KR (1) KR100522337B1 (tr)
CN (1) CN1105098C (tr)
AR (1) AR010366A1 (tr)
AT (1) ATE207053T1 (tr)
AU (1) AU725683B2 (tr)
BR (1) BR9713950A (tr)
CA (1) CA2273286A1 (tr)
CZ (1) CZ296780B6 (tr)
DE (1) DE69707503T2 (tr)
DK (1) DK0946497T3 (tr)
EE (1) EE03762B1 (tr)
EG (1) EG21486A (tr)
ES (1) ES2163806T3 (tr)
GB (1) GB9626319D0 (tr)
HU (1) HUP0000420A3 (tr)
ID (1) ID23994A (tr)
IL (1) IL130425A (tr)
IS (1) IS5059A (tr)
MY (1) MY115259A (tr)
NO (1) NO993065L (tr)
NZ (1) NZ335870A (tr)
PL (1) PL191196B1 (tr)
PT (1) PT946497E (tr)
RU (1) RU2190597C2 (tr)
SI (1) SI0946497T1 (tr)
SK (1) SK283033B6 (tr)
TR (1) TR199901394T2 (tr)
TW (1) TW415931B (tr)
WO (1) WO1998027052A1 (tr)
ZA (1) ZA9711057B (tr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100826497B1 (ko) 2007-01-22 2008-05-02 삼성전자주식회사 전력 소모를 줄이기 위한 반도체 메모리 장치의 입출력센스 앰프 회로

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE955508C (de) * 1954-07-28 1957-01-03 Cilag Ag Verfahren zur Herstellung von antikonvulsivisch wirkenden Carbonsaeureamiden
IL84305A (en) * 1987-02-06 1992-01-15 Fisons Corp 2-aminoacetamide derivatives

Also Published As

Publication number Publication date
EE9900257A (et) 1999-12-15
DE69707503D1 (de) 2001-11-22
EP0946497B1 (en) 2001-10-17
EG21486A (en) 2001-11-28
PT946497E (pt) 2002-03-28
JP2002512595A (ja) 2002-04-23
RU2190597C2 (ru) 2002-10-10
ATE207053T1 (de) 2001-11-15
AR010366A1 (es) 2000-06-07
CA2273286A1 (en) 1998-06-25
SK65699A3 (en) 1999-11-08
CZ219899A3 (cs) 1999-11-17
AU5352498A (en) 1998-07-15
WO1998027052A1 (en) 1998-06-25
HUP0000420A3 (en) 2000-09-28
US6063962A (en) 2000-05-16
KR20000069552A (ko) 2000-11-25
KR100522337B1 (ko) 2005-10-19
NZ335870A (en) 2001-05-25
HUP0000420A2 (hu) 2000-08-28
DE69707503T2 (de) 2002-05-16
EP0946497A1 (en) 1999-10-06
CN1105098C (zh) 2003-04-09
SK283033B6 (sk) 2003-02-04
MY115259A (en) 2003-04-30
CZ296780B6 (cs) 2006-06-14
NO993065D0 (no) 1999-06-21
IS5059A (is) 1999-05-28
IL130425A0 (en) 2000-06-01
ID23994A (id) 2000-06-14
DK0946497T3 (da) 2001-12-17
PL191196B1 (pl) 2006-03-31
ZA9711057B (en) 1998-06-19
NO993065L (no) 1999-06-21
SI0946497T1 (en) 2002-06-30
GB9626319D0 (en) 1997-02-05
IL130425A (en) 2003-02-12
TW415931B (en) 2000-12-21
PL333919A1 (en) 2000-01-31
AU725683B2 (en) 2000-10-19
BR9713950A (pt) 2000-03-21
EE03762B1 (et) 2002-06-17
ES2163806T3 (es) 2002-02-01
CN1240420A (zh) 2000-01-05

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