TR199802492T2 - L(-) karnitin ve alkanol L(-) karnitinin stabl higroskopik olmayan tuzlari, onlarin hazirlanmasi için bir islem ve böyle tuzlari içeren kati, agizdan alinabilen bilesimler. - Google Patents

L(-) karnitin ve alkanol L(-) karnitinin stabl higroskopik olmayan tuzlari, onlarin hazirlanmasi için bir islem ve böyle tuzlari içeren kati, agizdan alinabilen bilesimler.

Info

Publication number
TR199802492T2
TR199802492T2 TR1998/02492T TR9802492T TR199802492T2 TR 199802492 T2 TR199802492 T2 TR 199802492T2 TR 1998/02492 T TR1998/02492 T TR 1998/02492T TR 9802492 T TR9802492 T TR 9802492T TR 199802492 T2 TR199802492 T2 TR 199802492T2
Authority
TR
Turkey
Prior art keywords
carnitine
salts
alkanol
preparation
solid
Prior art date
Application number
TR1998/02492T
Other languages
English (en)
Inventor
Fassi Aldo
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI961116 external-priority patent/IT1283086B1/it
Priority claimed from IT97MI000409A external-priority patent/IT1289974B1/it
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of TR199802492T2 publication Critical patent/TR199802492T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/285—Polyhydroxy dicarboxylic acids having five or more carbon atoms, e.g. saccharic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Bu bulus, L(-) karnitin ve alkanol L(-) karnitinin stabl higroskopik olmayan tuzlariyla, onlarin hazirlanmasi için bir islemle ve böyle tuzlari içeren kati, agizdan alinabilen bilesimlerle ilgilidir. Bu, bulusun bilesimleri, farmasötik bilesikler, reçetesiz olarak satilan (OTC) bilesimler,besin tamamlayicilari, diyet tamamlayicilari, saglik besinleri, tibbi besinler, nutrasötikler, veteriner ürünleri ve yemler olarak ortaya çikabilmektedir.
TR1998/02492T 1996-05-31 1997-05-26 L(-) karnitin ve alkanol L(-) karnitinin stabl higroskopik olmayan tuzlari, onlarin hazirlanmasi için bir islem ve böyle tuzlari içeren kati, agizdan alinabilen bilesimler. TR199802492T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI961116 IT1283086B1 (it) 1996-05-31 1996-05-31 Sali stabili e non igroscopici di l-carnitina e di alcanoil l-carnitine
IT97MI000409A IT1289974B1 (it) 1997-02-25 1997-02-25 Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine

Publications (1)

Publication Number Publication Date
TR199802492T2 true TR199802492T2 (tr) 1999-02-22

Family

ID=26331398

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/02492T TR199802492T2 (tr) 1996-05-31 1997-05-26 L(-) karnitin ve alkanol L(-) karnitinin stabl higroskopik olmayan tuzlari, onlarin hazirlanmasi için bir islem ve böyle tuzlari içeren kati, agizdan alinabilen bilesimler.

Country Status (24)

Country Link
US (1) US5952379A (tr)
EP (1) EP0914315B1 (tr)
JP (1) JP4160634B2 (tr)
CN (1) CN1177807C (tr)
AT (1) ATE200479T1 (tr)
AU (1) AU718308B2 (tr)
BR (1) BR9709627A (tr)
CZ (1) CZ290902B6 (tr)
DE (1) DE69704561T2 (tr)
DK (1) DK0914315T3 (tr)
EE (1) EE03604B1 (tr)
ES (1) ES2156381T3 (tr)
GR (1) GR3035969T3 (tr)
HK (1) HK1024463A1 (tr)
HU (1) HU228008B1 (tr)
IL (1) IL127266A (tr)
IS (1) IS2085B (tr)
NO (1) NO323593B1 (tr)
NZ (1) NZ333061A (tr)
PL (1) PL188558B1 (tr)
PT (1) PT914315E (tr)
SK (1) SK283105B6 (tr)
TR (1) TR199802492T2 (tr)
WO (1) WO1997046512A1 (tr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1289974B1 (it) * 1997-02-25 1998-10-19 Aldo Fassi Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine
IT1312018B1 (it) * 1999-03-19 2002-04-04 Fassi Aldo Procedimento migliorato per la produzione di sali non igroscopicidella l(-)-carnitina.
AU770563B2 (en) * 1999-09-03 2004-02-26 Alfasigma S.p.A Ultrafine l-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same
IT1316988B1 (it) 2000-02-10 2003-05-26 Sigma Tau Ind Farmaceuti Procedimento migliorato di preparazione industriale di mucati dellal-carnitina e di alcanoil l-carnitine.
US8252309B2 (en) * 2000-04-04 2012-08-28 Sigma-Tau Industrie Farmaceutiche Riunite Spa Dietary supplement energy-providing to skeletal muscles
ITRM20010029A1 (it) * 2001-01-23 2002-07-23 Aldo Fassi Sali metallici di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per
ITRM20010030A1 (it) * 2001-01-23 2002-07-23 Aldo Fassi Sali di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per la loro pr
ITRM20010044A1 (it) 2001-01-29 2002-07-29 Sigma Tau Healthscience Spa Integratore alimentare ad effetto dimagrante.
DE10133200A1 (de) * 2001-07-07 2003-01-23 Beiersdorf Ag Carnitin enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut
ITRM20020055A1 (it) * 2002-02-04 2003-08-04 Aldo Fassi Sali metallici di carnitine, integratori dietetici/nutritivi che li contengono e kit dietetici per contrastare disturbi sessuali in soggetti
JP2006111550A (ja) * 2004-10-13 2006-04-27 Nisshin Pharma Inc カルニチン含有製品
ES2385046T3 (es) * 2005-07-05 2012-07-17 Lonza Ag Procedimiento de secado por pulverización para producir un polvo o granulado de carnitina seco
CN101209975B (zh) 2006-12-29 2010-12-01 沈阳科硕营养科技有限公司 左旋肉碱富马酸钙及其制备方法与用途
EP2425834A1 (en) * 2010-09-06 2012-03-07 Lonza Ltd. Process for the production of l-carnitine tartrate
CN102911067A (zh) * 2011-08-04 2013-02-06 广州市奥海生物科技有限公司 左旋肉碱丙酮酸盐及其制备方法与用途
CN102911068A (zh) * 2011-08-04 2013-02-06 广州市奥海生物科技有限公司 左旋肉碱l-苹果酸盐及其制备方法与用途
JP6393310B2 (ja) * 2013-04-26 2018-09-19 サノフイＳａｎｏｆｉ ５−クロロ−チオフェン−２−カルボン酸［（ｓ）−２−［メチル−３−（２−オキソ−ピロリジン−１−イル）−ベンゼンスルホニルアミノ］−３−（４−メチル−ピペラジン−１−イル）−３−オキソ−プロプリル］アミドの酒石酸塩
CN103664667A (zh) * 2013-12-16 2014-03-26 天津天成制药有限公司 乙酰左旋肉碱硝酸盐的制备方法
CN106045919B (zh) * 2016-07-07 2022-08-09 湖北楚维药业有限公司 一种左旋肉碱乳清酸盐的制备方法
CN106748845B (zh) * 2016-12-23 2018-11-20 东北制药集团股份有限公司 一种左旋肉碱盐微粉的制备方法
CN112250588B (zh) * 2020-11-06 2023-03-31 哈尔滨工业大学（深圳） 一种左旋肉碱离子液体及其制备方法、应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5656M (tr) * 1965-10-12 1967-12-26
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
US5073376A (en) * 1989-12-22 1991-12-17 Lonza Ltd. Preparations containing l-carnitine
IT1258370B (it) * 1992-03-02 1996-02-26 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono.
IT1261808B (it) * 1993-07-06 1996-06-03 Impiego di l-carnitina o acido l-carnitine e valproato nel trattamentodei disosrdini convulsivi

Also Published As

Publication number Publication date
DK0914315T3 (da) 2001-06-05
PL330189A1 (en) 1999-04-26
ATE200479T1 (de) 2001-04-15
IL127266A0 (en) 1999-09-22
AU718308B2 (en) 2000-04-13
EP0914315B1 (en) 2001-04-11
NO985562D0 (no) 1998-11-27
IS2085B (is) 2006-02-15
SK164998A3 (en) 1999-05-07
PT914315E (pt) 2001-07-31
NO985562L (no) 1999-01-05
US5952379A (en) 1999-09-14
EE9800422A (et) 1999-06-15
CN1177807C (zh) 2004-12-01
JP2000514413A (ja) 2000-10-31
HUP9903455A2 (hu) 2000-03-28
CZ290902B6 (cs) 2002-11-13
JP4160634B2 (ja) 2008-10-01
NO323593B1 (no) 2007-06-11
DE69704561T2 (de) 2001-08-09
BR9709627A (pt) 1999-08-10
CZ391598A3 (cs) 1999-04-14
HK1024463A1 (en) 2000-10-13
GR3035969T3 (en) 2001-08-31
WO1997046512A1 (en) 1997-12-11
DE69704561D1 (de) 2001-05-17
ES2156381T3 (es) 2001-06-16
AU2961297A (en) 1998-01-05
IL127266A (en) 2002-09-12
SK283105B6 (sk) 2003-02-04
EP0914315A1 (en) 1999-05-12
HU228008B1 (en) 2012-08-28
EE03604B1 (et) 2002-02-15
NZ333061A (en) 1999-05-28
IS4914A (is) 1998-11-30
PL188558B1 (pl) 2005-02-28
HUP9903455A3 (en) 2001-01-29
CN1244191A (zh) 2000-02-09

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